increased papilloma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of benign tumors consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic epithelial cells occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0002014)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002014
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Genes

32 gene mutations causing the increased papilloma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
AURKB aurora kinase B
CD34 CD34 molecule
CDK11A cyclin-dependent kinase 11A
CDKN2A cyclin-dependent kinase inhibitor 2A
CYLD cylindromatosis (turban tumor syndrome)
EGR1 early growth response 1
ERRFI1 ERBB receptor feedback inhibitor 1
FHIT fragile histidine triad
GSTP1 glutathione S-transferase pi 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF10 Kruppel-like factor 10
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT14 keratin 14, type I
KRT9 keratin 9, type I
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MMP8 matrix metallopeptidase 8
PAQR3 progestin and adipoQ receptor family member III
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PPARD peroxisome proliferator-activated receptor delta
PRKCA protein kinase C, alpha
PRKCH protein kinase C, eta
RINT1 RAD50 interactor 1
SFN stratifin
STAG1 stromal antigen 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TTC7A tetratricopeptide repeat domain 7A
XPA xeroderma pigmentosum, complementation group A