increased pancreatic beta cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal number of the cells of the pancreas that secrete insulin (Mammalian Phenotype Ontology, MP_0003645)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003645
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Genes

16 gene mutations causing the increased pancreatic beta cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ARX aristaless related homeobox
ATXN2 ataxin 2
BRD2 bromodomain containing 2
CADM1 cell adhesion molecule 1
CDK4 cyclin-dependent kinase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
INS insulin
LEP leptin
LEPR leptin receptor
MEN1 multiple endocrine neoplasia I
OSMR oncostatin M receptor
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
SIDT2 SID1 transmembrane family, member 2