increased ovary tumor incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of neoplams in the ovary occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0008000)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008000
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Genes

21 gene mutations causing the increased ovary tumor incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AMHR2 anti-Mullerian hormone receptor, type II
ATAD5 ATPase family, AAA domain containing 5
ATM ATM serine/threonine kinase
CUL9 cullin 9
DCLRE1A DNA cross-link repair 1A
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
HELQ helicase, POLQ-like
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
INHA inhibin, alpha
LATS1 large tumor suppressor kinase 1
MCM8 minichromosome maintenance complex component 8
MCM9 minichromosome maintenance complex component 9
MEN1 multiple endocrine neoplasia I
PCSK6 proprotein convertase subtilisin/kexin type 6
RINT1 RAD50 interactor 1
SAV1 salvador family WW domain containing protein 1
SMAD4 SMAD family member 4
SPTBN1 spectrin, beta, non-erythrocytic 1
TOM1L2 target of myb1-like 2 (chicken)
TP53 tumor protein p53