increased osteoblast cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than average number of skeletogenic cells that secrete osteoid, are capable of producing mineralized (hydroxyapatite) matrix, are located adjacent to or within osteoid tissue, and arise from the transformation of a preosteoblast cell (Mammalian Phenotype Ontology, MP_0004988)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004988
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Genes

28 gene mutations causing the increased osteoblast cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
ARNTL aryl hydrocarbon receptor nuclear translocator-like
CLCN7 chloride channel, voltage-sensitive 7
CNN1 calponin 1, basic, smooth muscle
EBF1 early B-cell factor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
GATA1 GATA binding protein 1 (globin transcription factor 1)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IDUA iduronidase, alpha-L-
IL6ST interleukin 6 signal transducer
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRAK3 interleukin-1 receptor-associated kinase 3
IRS1 insulin receptor substrate 1
KLF10 Kruppel-like factor 10
NFE2 nuclear factor, erythroid 2
NPR3 natriuretic peptide receptor 3
NXN nucleoredoxin
PER1 period circadian clock 1
PPARG peroxisome proliferator-activated receptor gamma
PTHLH parathyroid hormone-like hormone
SH3BP2 SH3-domain binding protein 2
TNF tumor necrosis factor
TOB1 transducer of ERBB2, 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor