increased neuron number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses (Mammalian Phenotype Ontology, MP_0008947)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008947
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Genes

62 gene mutations causing the increased neuron number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATOH7 atonal homolog 7 (Drosophila)
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BARHL2 BarH-like homeobox 2
BAX BCL2-associated X protein
BDNF brain-derived neurotrophic factor
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHAT choline O-acetyltransferase
CHD7 chromodomain helicase DNA binding protein 7
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CRYBB2 crystallin, beta B2
CUX2 cut-like homeobox 2
DFNA5 deafness, autosomal dominant 5
DLL1 delta-like 1 (Drosophila)
DSCAM Down syndrome cell adhesion molecule
DSCAML1 Down syndrome cell adhesion molecule like 1
EMX2 empty spiracles homeobox 2
EYA1 EYA transcriptional coactivator and phosphatase 1
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FOXN4 forkhead box N4
FYN FYN proto-oncogene, Src family tyrosine kinase
GDF11 growth differentiation factor 11
GFI1 growth factor independent 1 transcription repressor
GPHN gephyrin
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
IFT122 intraflagellar transport 122
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
JAG1 jagged 1
JAG2 jagged 2
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KIF5C kinesin family member 5C
LMX1B LIM homeobox transcription factor 1, beta
MAPT microtubule-associated protein tau
MBD4 methyl-CpG binding domain protein 4
MSX1 msh homeobox 1
NEUROD1 neuronal differentiation 1
NGFR nerve growth factor receptor
NKX2-2 NK2 homeobox 2
NKX2-8 NK2 homeobox 8
NOG noggin
NOTCH1 notch 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRL neural retina leucine zipper
PANX1 pannexin 1
PDCD1 programmed cell death 1
PHOX2A paired-like homeobox 2a
PITX3 paired-like homeodomain 3
POU4F2 POU class 4 homeobox 2
PRPH2 peripherin 2 (retinal degeneration, slow)
PTF1A pancreas specific transcription factor, 1a
PTK7 protein tyrosine kinase 7 (inactive)
RORB RAR-related orphan receptor B
SIX1 SIX homeobox 1
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
UNC5A unc-5 homolog A (C. elegans)
VANGL2 VANGL planar cell polarity protein 2