increased natural killer cell mediated cytotoxicity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased ability of directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors (Mammalian Phenotype Ontology, MP_0003080)
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8 gene mutations causing the increased natural killer cell mediated cytotoxicity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD244 CD244 molecule, natural killer cell receptor 2B4
CD247 CD247 molecule
CLNK cytokine-dependent hematopoietic cell linker
RAG2 recombination activating gene 2
RHBDD3 rhomboid domain containing 3
SH2D1B SH2 domain containing 1B
TBX21 T-box 21
TYROBP TYRO protein tyrosine kinase binding protein