increased metanephric mesenchyme apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the number of cells of the metanephric mesenchyme (MM) undergoing programmed cell death; usually due to failure of MM cells to interact with the ureteric bud (UB) tips after UB invasion (Mammalian Phenotype Ontology, MP_0011386)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011386
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Genes

14 gene mutations causing the increased metanephric mesenchyme apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AMER1 APC membrane recruitment protein 1
BCL2 B-cell CLL/lymphoma 2
BMP4 bone morphogenetic protein 4
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CTNNBIP1 catenin, beta interacting protein 1
EMX2 empty spiracles homeobox 2
EYA1 EYA transcriptional coactivator and phosphatase 1
FRAS1 Fraser extracellular matrix complex subunit 1
GREM1 gremlin 1, DAN family BMP antagonist
ILK integrin-linked kinase
OSR1 odd-skipped related transciption factor 1
RET ret proto-oncogene
SALL1 spalt-like transcription factor 1
WT1 Wilms tumor 1