increased memory t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the number of distinctly differentiated long-lived T cells that have the phenotype CD45RO-positive and CD127-positive (Mammalian Phenotype Ontology, MP_0008049)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008049
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Genes

37 gene mutations causing the increased memory t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CXCR2 chemokine (C-X-C motif) receptor 2
DCK deoxycytidine kinase
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEF6 differentially expressed in FDCP 6 homolog (mouse)
E2F2 E2F transcription factor 2
FBXO7 F-box protein 7
GRAP2 GRB2-related adaptor protein 2
IL20RB interleukin 20 receptor beta
IL2RA interleukin 2 receptor, alpha
IRF2 interferon regulatory factor 2
ITK IL2-inducible T-cell kinase
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
MAN2A1 mannosidase, alpha, class 2A, member 1
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
PRKCH protein kinase C, eta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
SGMS1 sphingomyelin synthase 1
STK17B serine/threonine kinase 17b
SYK spleen tyrosine kinase
SYTL1 synaptotagmin-like 1
TESPA1 thymocyte expressed, positive selection associated 1
THEMIS thymocyte selection associated
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
UNC93B1 unc-93 homolog B1 (C. elegans)
WDTC1 WD and tetratricopeptide repeats 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZC3H12A zinc finger CCCH-type containing 12A