|Dataset||MPO Gene-Phenotype Associations|
|Category||disease or phenotype associations|
|Description||greater than the expected number of rare testicular tumors of the male gonadal interstitium, occurring in a specific population in a given time period; Leydig cell tumors are frequently hormonally active, leading to feminizing or virilizing syndromes; Leydig cell tumors comprise 1-3% of all testicular neoplasms, can be pure or mixed with other sex cord-stromal or germ cell tumors, and are usually benign, although malignant variants also occur (Mammalian Phenotype Ontology, MP_0009592)|
|Downloads & Tools|
3 gene mutations causing the increased leydig cell tumor incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.