increased leiomyosarcoma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of a malignant tumor derived from smooth (nonstriated) muscle, occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0002035)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002035
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Genes

4 gene mutations causing the increased leiomyosarcoma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
PLK3 polo-like kinase 3
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
TP53 tumor protein p53
TSC1 tuberous sclerosis 1