increased lean body mass Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater amount of the fat-free physical bulk or volume of the body including all its components except adipose (fat) tissue (Mammalian Phenotype Ontology, MP_0003960)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003960
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Genes

70 gene mutations causing the increased lean body mass phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACOT13 acyl-CoA thioesterase 13
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ANKRD26 ankyrin repeat domain 26
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX6 chromobox homolog 6
CD14 CD14 molecule
CD200 CD200 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CISD2 CDGSH iron sulfur domain 2
COL1A1 collagen, type I, alpha 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDR2 discoidin domain receptor tyrosine kinase 2
DLL1 delta-like 1 (Drosophila)
ELMOD1 ELMO/CED-12 domain containing 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERP44 endoplasmic reticulum protein 44
ESRRA estrogen-related receptor alpha
FAM117B family with sequence similarity 117, member B
FAM134C family with sequence similarity 134, member C
FBXO11 F-box protein 11
FGF21 fibroblast growth factor 21
FTO fat mass and obesity associated
GNAS GNAS complex locus
GPR21 G protein-coupled receptor 21
GPR22 G protein-coupled receptor 22
GRB10 growth factor receptor-bound protein 10
GSK3A glycogen synthase kinase 3 alpha
KIAA1549L KIAA1549-like
KLF15 Kruppel-like factor 15
L3MBTL2 l(3)mbt-like 2 (Drosophila)
MARC2 mitochondrial amidoxime reducing component 2
MC4R melanocortin 4 receptor
MCHR1 melanin-concentrating hormone receptor 1
MECOM MDS1 and EVI1 complex locus
METTL24 methyltransferase like 24
MRAP2 melanocortin 2 receptor accessory protein 2
MSTN myostatin
MYBPC3 myosin binding protein C, cardiac
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NXN nucleoredoxin
PBX3 pre-B-cell leukemia homeobox 3
PCNA proliferating cell nuclear antigen
PITX3 paired-like homeodomain 3
PLIN1 perilipin 1
PNLIP pancreatic lipase
POMC proopiomelanocortin
PTRF polymerase I and transcript release factor
PYY peptide YY
ROR2 receptor tyrosine kinase-like orphan receptor 2
SERF1A small EDRK-rich factor 1A (telomeric)
SERTAD2 SERTA domain containing 2
SH3KBP1 SH3-domain kinase binding protein 1
SIRT2 sirtuin 2
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5
SMCO2 single-pass membrane protein with coiled-coil domains 2
SNAP47 synaptosomal-associated protein, 47kDa
TBC1D2B TBC1 domain family, member 2B
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UMOD uromodulin
USH1C Usher syndrome 1C (autosomal recessive, severe)
VGF VGF nerve growth factor inducible
VIPR2 vasoactive intestinal peptide receptor 2
XYLB xylulokinase homolog (H. influenzae)