increased inflammatory response Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A abnormal increase in the inflammatory response to injury or infection. (Human Phenotype Ontology, HP_0012649)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001846
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Genes

752 gene mutations causing the increased inflammatory response phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A2M alpha-2-macroglobulin
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAN aggrecan
ACE angiotensin I converting enzyme
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACKR2 atypical chemokine receptor 2
ACKR3 atypical chemokine receptor 3
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACVR1 activin A receptor, type I
ADAM17 ADAM metallopeptidase domain 17
ADAM8 ADAM metallopeptidase domain 8
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADM adrenomedullin
ADORA2B adenosine A2b receptor
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AIF1 allograft inflammatory factor 1
AIRE autoimmune regulator
AK7 adenylate kinase 7
AKAP12 A kinase (PRKA) anchor protein 12
ALMS1 Alstrom syndrome protein 1
ALOX15 arachidonate 15-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
AMPD3 adenosine monophosphate deaminase 3
ANK1 ankyrin 1, erythrocytic
ANKH ANKH inorganic pyrophosphate transport regulator
ANXA1 annexin A1
ANXA7 annexin A7
APCS amyloid P component, serum
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA4 apolipoprotein A-IV
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APRT adenine phosphoribosyltransferase
AQP12A aquaporin 12A
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARID5B AT rich interactive domain 5B (MRF1-like)
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL3 ADP-ribosylation factor-like 3
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB2 arrestin, beta 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATF2 activating transcription factor 2
ATF3 activating transcription factor 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP7A ATPase, Cu++ transporting, alpha polypeptide
B2M beta-2-microglobulin
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BAG4 BCL2-associated athanogene 4
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BGN biglycan
BIN3 bridging integrator 3
BLMH bleomycin hydrolase
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
BMX BMX non-receptor tyrosine kinase
BPIFA1 BPI fold containing family A, member 1
BRCA1 breast cancer 1, early onset
BSG basigin (Ok blood group)
BTK Bruton agammaglobulinemia tyrosine kinase
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1QA complement component 1, q subcomponent, A chain
C1QTNF3 C1q and tumor necrosis factor related protein 3
C3 complement component 3
C3AR1 complement component 3a receptor 1
C4A complement component 4A (Rodgers blood group)
C5AR2 complement component 5a receptor 2
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMP cathelicidin antimicrobial peptide
CARD11 caspase recruitment domain family, member 11
CASP12 caspase 12 (gene/pseudogene)
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBS cystathionine-beta-synthase
CBY1 chibby homolog 1 (Drosophila)
CCL13 chemokine (C-C motif) ligand 13
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD109 CD109 molecule
CD151 CD151 molecule (Raph blood group)
CD1D CD1d molecule
CD200 CD200 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD300LF CD300 molecule-like family member f
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD69 CD69 molecule
CD72 CD72 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CFB complement factor B
CFH complement factor H
CFP complement factor properdin
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD2 chromodomain helicase DNA binding protein 2
CHD7 chromodomain helicase DNA binding protein 7
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHSY1 chondroitin sulfate synthase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CIITA class II, major histocompatibility complex, transactivator
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CLEC4D C-type lectin domain family 4, member D
CLEC4G C-type lectin domain family 4, member G
CLEC5A C-type lectin domain family 5, member A
CLEC7A C-type lectin domain family 7, member A
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CLU clusterin
CMKLR1 chemerin chemokine-like receptor 1
COL11A1 collagen, type XI, alpha 1
COL13A1 collagen, type XIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A5 collagen, type IV, alpha 5
COL9A1 collagen, type IX, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
COMP cartilage oligomeric matrix protein
CORO1A coronin, actin binding protein, 1A
COX1
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CPB2 carboxypeptidase B2 (plasma)
CPN1 carboxypeptidase N, polypeptide 1
CR1L complement component (3b/4b) receptor 1-like
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRLF2 cytokine receptor-like factor 2
CROCC ciliary rootlet coiled-coil, rootletin
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSTB cystatin B (stefin B)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSE cathepsin E
CTSS cathepsin S
CTSV cathepsin V
CUX1 cut-like homeobox 1
CUZD1 CUB and zona pellucida-like domains 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYLD cylindromatosis (turban tumor syndrome)
CYS1 cystin 1
CYSLTR1 cysteinyl leukotriene receptor 1
CYTL1 cytokine-like 1
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DIAPH1 diaphanous-related formin 1
DKC1 dyskeratosis congenita 1, dyskerin
DMBT1 deleted in malignant brain tumors 1
DMD dystrophin
DNAH5 dynein, axonemal, heavy chain 5
DNASE1 deoxyribonuclease I
DPCD deleted in primary ciliary dyskinesia homolog (mouse)
DSC1 desmocollin 1
DSG3 desmoglein 3
DSG4 desmoglein 4
DST dystonin
DTX1 deltex 1, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP2 dual specificity phosphatase 2
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
EBI3 Epstein-Barr virus induced 3
EDA ectodysplasin A
EFS embryonal Fyn-associated substrate
EGR1 early growth response 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELOVL3 ELOVL fatty acid elongase 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPCAM epithelial cell adhesion molecule
EPHA1 EPH receptor A1
EREG epiregulin
ERN2 endoplasmic reticulum to nucleus signaling 2
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EYA4 EYA transcriptional coactivator and phosphatase 4
F11R F11 receptor
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADS2 fatty acid desaturase 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAIM Fas apoptotic inhibitory molecule
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBN1 fibrillin 1
FBXO11 F-box protein 11
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FERMT1 fermitin family member 1
FES FES proto-oncogene, tyrosine kinase
FFAR2 free fatty acid receptor 2
FGFR1 fibroblast growth factor receptor 1
FIGN fidgetin
FKBP11 FK506 binding protein 11, 19 kDa
FLG filaggrin
FMOD fibromodulin
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXN1 forkhead box N1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FTO fat mass and obesity associated
FYN FYN proto-oncogene, Src family tyrosine kinase
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GALC galactosylceramidase
GAST gastrin
GATA5 GATA binding protein 5
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GDNF glial cell derived neurotrophic factor
GFI1 growth factor independent 1 transcription repressor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJA1 gap junction protein, alpha 1, 43kDa
GLIS2 GLIS family zinc finger 2
GLMP glycosylated lysosomal membrane protein
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLM1 golgi membrane protein 1
GPC3 glypican 3
GPR132 G protein-coupled receptor 132
GPR15 G protein-coupled receptor 15
GPR34 G protein-coupled receptor 34
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPSM3 G-protein signaling modulator 3
GPX1 glutathione peroxidase 1
GPX7 glutathione peroxidase 7
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GSTK1 glutathione S-transferase kappa 1
GSTZ1 glutathione S-transferase zeta 1
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HABP2 hyaluronan binding protein 2
HAVCR1 hepatitis A virus cellular receptor 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HEXB hexosaminidase B (beta polypeptide)
HIC1 hypermethylated in cancer 1
HLA-A major histocompatibility complex, class I, A
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXA5 homeobox A5
HPGDS hematopoietic prostaglandin D synthase
HPS1 Hermansky-Pudlak syndrome 1
HR hair growth associated
HSPB1 heat shock 27kDa protein 1
HSPG2 heparan sulfate proteoglycan 2
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HYAL1 hyaluronoglucosaminidase 1
HYDIN HYDIN, axonemal central pair apparatus protein
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IDUA iduronidase, alpha-L-
IER3 immediate early response 3
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGFBP1 insulin-like growth factor binding protein 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL17A interleukin 17A
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL17RE interleukin 17 receptor E
IL18 interleukin 18
IL1R1 interleukin 1 receptor, type I
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL20RB interleukin 20 receptor beta
IL22 interleukin 22
IL22RA2 interleukin 22 receptor, alpha 2
IL23A interleukin 23, alpha subunit p19
IL25 interleukin 25
IL27 interleukin 27
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL33 interleukin 33
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
INHA inhibin, alpha
INHBB inhibin, beta B
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INS insulin
IRAK3 interleukin-1 receptor-associated kinase 3
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
ISL1 ISL LIM homeobox 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB6 integrin, beta 6
ITGB7 integrin, beta 7
JAK1 Janus kinase 1
JAK3 Janus kinase 3
JAM3 junctional adhesion molecule 3
JUND jun D proto-oncogene
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KIF1C kinesin family member 1C
KIF27 kinesin family member 27
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF15 Kruppel-like factor 15
KMT2E lysine (K)-specific methyltransferase 2E
KSR1 kinase suppressor of ras 1
LAMA2 laminin, alpha 2
LAMB2 laminin, beta 2 (laminin S)
LAMC2 laminin, gamma 2
LARGE like-glycosyltransferase
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LDLR low density lipoprotein receptor
LECT2 leukocyte cell-derived chemotaxin 2
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS9B lectin, galactoside-binding, soluble, 9B
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHCGR luteinizing hormone/choriogonadotropin receptor
LIF leukemia inhibitory factor
LIG4 ligase IV, DNA, ATP-dependent
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIMK2 LIM domain kinase 2
LIPA lipase A, lysosomal acid, cholesterol esterase
LOR loricrin
LPAR2 lysophosphatidic acid receptor 2
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
LTC4S leukotriene C4 synthase
LYN LYN proto-oncogene, Src family tyrosine kinase
LYST lysosomal trafficking regulator
LYZ lysozyme
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MARCO macrophage receptor with collagenous structure
MARK2 MAP/microtubule affinity-regulating kinase 2
MAT1A methionine adenosyltransferase I, alpha
MATN3 matrilin 3
MAVS mitochondrial antiviral signaling protein
MBTPS1 membrane-bound transcription factor peptidase, site 1
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MDK midkine (neurite growth-promoting factor 2)
MECOM MDS1 and EVI1 complex locus
MEFV Mediterranean fever
MEN1 multiple endocrine neoplasia I
MEP1A meprin A, alpha (PABA peptide hydrolase)
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MFSD8 major facilitator superfamily domain containing 8
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MILR1 mast cell immunoglobulin-like receptor 1
MIR122 microRNA 122
MIR140 microRNA 140
MIR155 microRNA 155
MIR223 microRNA 223
MME membrane metallo-endopeptidase
MMP10 matrix metallopeptidase 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPZL3 myelin protein zero-like 3
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
MTA2 metastasis associated 1 family, member 2
MTAP methylthioadenosine phosphorylase
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUT methylmalonyl CoA mutase
MYD88 myeloid differentiation primary response 88
MYH4 myosin, heavy chain 4, skeletal muscle
MYH9 myosin, heavy chain 9, non-muscle
NAGLU N-acetylglucosaminidase, alpha
NCF1 neutrophil cytosolic factor 1
NCKAP1L NCK-associated protein 1-like
NCOA3 nuclear receptor coactivator 3
NCOA5 nuclear receptor coactivator 5
NDFIP1 Nedd4 family interacting protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NIPBL Nipped-B homolog (Drosophila)
NLRC3 NLR family, CARD domain containing 3
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NLRX1 NLR family member X1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPAS3 neuronal PAS domain protein 3
NPC1 Niemann-Pick disease, type C1
NPHP3 nephronophthisis 3 (adolescent)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRTN neurturin
NTAN1 N-terminal asparagine amidase
OCLN occludin
OLFM4 olfactomedin 4
ORAI1 ORAI calcium release-activated calcium modulator 1
OSMR oncostatin M receptor
OSTM1 osteopetrosis associated transmembrane protein 1
OTC ornithine carbamoyltransferase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARG poly (ADP-ribose) glycohydrolase
PAX6 paired box 6
PAX7 paired box 7
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PDX1 pancreatic and duodenal homeobox 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PEX7 peroxisomal biogenesis factor 7
PFDN1 prefoldin subunit 1
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PGM3 phosphoglucomutase 3
PGR progesterone receptor
PHEX phosphate regulating endopeptidase homolog, X-linked
PHYH phytanoyl-CoA 2-hydroxylase
PIAS1 protein inhibitor of activated STAT, 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PILRA paired immunoglobin-like type 2 receptor alpha
PIP prolactin-induced protein
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKN1 protein kinase N1
PKP3 plakophilin 3
PLA2G2D phospholipase A2, group IID
PLA2G3 phospholipase A2, group III
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLG plasminogen
POLB polymerase (DNA directed), beta
POSTN periostin, osteoblast specific factor
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPT1 palmitoyl-protein thioesterase 1
PRDX3 peroxiredoxin 3
PRF1 perforin 1 (pore forming protein)
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKCD protein kinase C, delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROX1 prospero homeobox 1
PSAP prosaposin
PSIP1 PC4 and SFRS1 interacting protein 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTAFR platelet-activating factor receptor
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGES2 prostaglandin E synthase 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRN protein tyrosine phosphatase, receptor type, N
PTX3 pentraxin 3, long
PXDN peroxidasin
PYCARD PYD and CARD domain containing
RAD23B RAD23 homolog B (S. cerevisiae)
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP4 RAS guanyl releasing protein 4
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RC3H1 ring finger and CCCH-type domains 1
RCAN1 regulator of calcineurin 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REN renin
RETNLB resistin like beta
RGS13 regulator of G-protein signaling 13
RGS3 regulator of G-protein signaling 3
RHBDD3 rhomboid domain containing 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
RPL22 ribosomal protein L22
RPL38 ribosomal protein L38
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
SALL4 spalt-like transcription factor 4
SCARA5 scavenger receptor class A, member 5
SCARF1 scavenger receptor class F, member 1
SCP2 sterol carrier protein 2
SCTR secretin receptor
SDC1 syndecan 1
SEC23B Sec23 homolog B (S. cerevisiae)
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA1 surfactant protein A1
SFTPC surfactant protein C
SFTPD surfactant protein D
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGPL1 sphingosine-1-phosphate lyase 1
SH3BP2 SH3-domain binding protein 2
SH3PXD2B SH3 and PX domains 2B
SHARPIN SHANK-associated RH domain interactor
SIAE sialic acid acetylesterase
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SIRT6 sirtuin 6
SIRT7 sirtuin 7
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SMAD9 SMAD family member 9
SMTN smoothelin
SNAI2 snail family zinc finger 2
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD3 superoxide dismutase 3, extracellular
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPDEF SAM pointed domain containing ETS transcription factor
SPEF2 sperm flagellar 2
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRXN1 sulfiredoxin 1
SSBP2 single-stranded DNA binding protein 2
SSTR4 somatostatin receptor 4
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIP1 stress-induced phosphoprotein 1
STK36 serine/threonine kinase 36
SUMF1 sulfatase modifying factor 1
SYCN syncollin
SYK spleen tyrosine kinase
SYNE1 spectrin repeat containing, nuclear envelope 1
SYT7 synaptotagmin VII
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TACR1 tachykinin receptor 1
TANK TRAF family member-associated NFKB activator
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBC1D23 TBC1 domain family, member 23
TBK1 TANK-binding kinase 1
TBX1 T-box 1
TBX21 T-box 21
TBXA2R thromboxane A2 receptor
TDRD7 tudor domain containing 7
TET2 tet methylcytosine dioxygenase 2
TFF3 trefoil factor 3 (intestinal)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGIF1 TGFB-induced factor homeobox 1
THBD thrombomodulin
THBS1 thrombospondin 1
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TICAM1 toll-like receptor adaptor molecule 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TK1 thymidine kinase 1, soluble
TKTL1 transketolase-like 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMEM79 transmembrane protein 79
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1
TNS1 tensin 1
TNS2 tensin 2
TOM1L2 target of myb1-like 2 (chicken)
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOP3B topoisomerase (DNA) III beta
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TPSAB1 tryptase alpha/beta 1
TRAF3IP2 TRAF3 interacting protein 2
TRAF4 TNF receptor-associated factor 4
TRAFD1 TRAF-type zinc finger domain containing 1
TREML1 triggering receptor expressed on myeloid cells-like 1
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
TROVE2 TROVE domain family, member 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSC22D3 TSC22 domain family, member 3
TSLP thymic stromal lymphopoietin
TSTA3 tissue specific transplantation antigen P35B
TTC7A tetratricopeptide repeat domain 7A
TTLL1 tubulin tyrosine ligase-like family member 1
TTN titin
TUSC2 tumor suppressor candidate 2
TYK2 tyrosine kinase 2
TYROBP TYRO protein tyrosine kinase binding protein
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBE3B ubiquitin protein ligase E3B
ULK4 unc-51 like kinase 4
UNC93B1 unc-93 homolog B1 (C. elegans)
UOX urate oxidase, pseudogene
USP18 ubiquitin specific peptidase 18
USP25 ubiquitin specific peptidase 25
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIP vasoactive intestinal peptide
VIPR2 vasoactive intestinal peptide receptor 2
WAS Wiskott-Aldrich syndrome
WDR1 WD repeat domain 1
WDR83 WD repeat domain 83
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1
WWTR1 WW domain containing transcription regulator 1
XCL1 chemokine (C motif) ligand 1
XDH xanthine dehydrogenase
YIPF6 Yip1 domain family, member 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFP36 ZFP36 ring finger protein
ZNF148 zinc finger protein 148