increased incidence of tumors by ionizing radiation induction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description higher than normal frequency of tumor incidence induced by radiation in which the individual particle or photon carries sufficient energy to completely remove an electron from its orbit; common types of this radiation include gamma-rays and X-rays (Mammalian Phenotype Ontology, MP_0004500)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004500
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Genes

16 gene mutations causing the increased incidence of tumors by ionizing radiation induction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BIN3 bridging integrator 3
BRCA1 breast cancer 1, early onset
CDC25A cell division cycle 25A
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
GADD45A growth arrest and DNA-damage-inducible, alpha
HMGN1 high mobility group nucleosome binding domain 1
MTF1 metal-regulatory transcription factor 1
NBN nibrin
PER2 period circadian clock 2
PTCH1 patched 1
PTEN phosphatase and tensin homolog
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
UIMC1 ubiquitin interaction motif containing 1