increased igg1 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal immunoglobulin class G1 level (Mammalian Phenotype Ontology, MP_0008499)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008499
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Genes

70 gene mutations causing the increased igg1 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADCY9 adenylate cyclase 9
AMPD3 adenosine monophosphate deaminase 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BHLHE40 basic helix-loop-helix family, member e40
BTLA B and T lymphocyte associated
CABIN1 calcineurin binding protein 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCL13 chemokine (C-C motif) ligand 13
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD22 CD22 molecule
CD274 CD274 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CYLD cylindromatosis (turban tumor syndrome)
DLK1 delta-like 1 homolog (Drosophila)
DUSP4 dual specificity phosphatase 4
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCRLA Fc receptor-like A
FCRLB Fc receptor-like B
FLG filaggrin
FOXP3 forkhead box P3
GABPB2 GA binding protein transcription factor, beta subunit 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GAP43 growth associated protein 43
GPR132 G protein-coupled receptor 132
HLA-DOA major histocompatibility complex, class II, DO alpha
IFNG interferon, gamma
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL13RA1 interleukin 13 receptor, alpha 1
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL6ST interleukin 6 signal transducer
JAK1 Janus kinase 1
LAT linker for activation of T cells
LAX1 lymphocyte transmembrane adaptor 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MIR150 microRNA 150
MYD88 myeloid differentiation primary response 88
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
PKN1 protein kinase N1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKCD protein kinase C, delta
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RETNLB resistin like beta
RGS13 regulator of G-protein signaling 13
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SIAE sialic acid acetylesterase
SNX5 sorting nexin 5
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TANK TRAF family member-associated NFKB activator
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNIP1 TNFAIP3 interacting protein 1
TRAF3IP2 TRAF3 interacting protein 2
UXS1 UDP-glucuronate decarboxylase 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZC3H12A zinc finger CCCH-type containing 12A