increased hepatoma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of malignant tumors composed of neoplastic liver cells in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0010264)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010264
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Genes

16 gene mutations causing the increased hepatoma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
AHR aryl hydrocarbon receptor
AURKA aurora kinase A
BRCA1 breast cancer 1, early onset
CAT catalase
CCNG1 cyclin G1
CDC20 cell division cycle 20
DNA2 DNA replication helicase/nuclease 2
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FANCM Fanconi anemia, complementation group M
NF1 neurofibromin 1
SAV1 salvador family WW domain containing protein 1
SOCS1 suppressor of cytokine signaling 1
SRPX sushi-repeat containing protein, X-linked
TNK1 tyrosine kinase, non-receptor, 1
USP44 ubiquitin specific peptidase 44