increased hepatocyte apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the number of hepatocytes undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0003887)
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38 gene mutations causing the increased hepatocyte apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
CBS cystathionine-beta-synthase
CCR2 chemokine (C-C motif) receptor 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPO erythropoietin
EPOR erythropoietin receptor
ERCC1 excision repair cross-complementation group 1
FAIM Fas apoptotic inhibitory molecule
GLMP glycosylated lysosomal membrane protein
IGFBP1 insulin-like growth factor binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL6R interleukin 6 receptor
IQGAP2 IQ motif containing GTPase activating protein 2
JUN jun proto-oncogene
LDLR low density lipoprotein receptor
MAP2K4 mitogen-activated protein kinase kinase 4
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCOA5 nuclear receptor coactivator 5
NCOA6 nuclear receptor coactivator 6
NFE2L2 nuclear factor, erythroid 2-like 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
POLB polymerase (DNA directed), beta
RB1CC1 RB1-inducible coiled-coil 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGN regucalcin
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SOD2 superoxide dismutase 2, mitochondrial
SUMF1 sulfatase modifying factor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNIP1 TNFAIP3 interacting protein 1
VASN vasorin
XBP1 X-box binding protein 1