increased hepatocellular carcinoma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003331
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Genes

54 gene mutations causing the increased hepatocellular carcinoma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACOX1 acyl-CoA oxidase 1, palmitoyl
ANXA7 annexin A7
APC adenomatous polyposis coli
ATM ATM serine/threonine kinase
ATP11C ATPase, class VI, type 11C
BECN1 beclin 1, autophagy related
BHLHA15 basic helix-loop-helix family, member a15
BHMT betaine--homocysteine S-methyltransferase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CBX7 chromobox homolog 7
CCNDBP1 cyclin D-type binding-protein 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CERS2 ceramide synthase 2
EAF2 ELL associated factor 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FBXO4 F-box protein 4
FHIT fragile histidine triad
FOXM1 forkhead box M1
GNMT glycine N-methyltransferase
GTF2IRD1 GTF2I repeat domain containing 1
HIC1 hypermethylated in cancer 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IQGAP2 IQ motif containing GTPase activating protein 2
LZTS1 leucine zipper, putative tumor suppressor 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MC4R melanocortin 4 receptor
MCM4 minichromosome maintenance complex component 4
MCM9 minichromosome maintenance complex component 9
MIR122 microRNA 122
MZF1 myeloid zinc finger 1
NCOA5 nuclear receptor coactivator 5
NR1H4 nuclear receptor subfamily 1, group H, member 4
PRDX1 peroxiredoxin 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RGPD1 RANBP2-like and GRIP domain containing 1
RINT1 RAD50 interactor 1
S100A4 S100 calcium binding protein A4
SIRT2 sirtuin 2
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SPTBN1 spectrin, beta, non-erythrocytic 1
STAG1 stromal antigen 1
STK11 serine/threonine kinase 11
TNK1 tyrosine kinase, non-receptor, 1
TP53 tumor protein p53
TPX2 TPX2, microtubule-associated
TRIM24 tripartite motif containing 24
TRIM62 tripartite motif containing 62
TXNIP thioredoxin interacting protein
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats