increased hematopoietic cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than expected number of cells of the hematopoietic lineage (Mammalian Phenotype Ontology, MP_0011181)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011181
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Genes

776 gene mutations causing the increased hematopoietic cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACKR4 atypical chemokine receptor 4
ACSL3 acyl-CoA synthetase long-chain family member 3
ADA adenosine deaminase
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADGRB1 adhesion G protein-coupled receptor B1
ADGRE5 adhesion G protein-coupled receptor E5
ADGRF5 adhesion G protein-coupled receptor F5
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRM1 adhesion regulating molecule 1
AGR2 anterior gradient 2
AGTR1 angiotensin II receptor, type 1
AHSP alpha hemoglobin stabilizing protein
AICDA activation-induced cytidine deaminase
AIRE autoimmune regulator
AKAP13 A kinase (PRKA) anchor protein 13
AKAP9 A kinase (PRKA) anchor protein 9
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALOX15 arachidonate 15-lipoxygenase
AMPD3 adenosine monophosphate deaminase 3
ANK1 ankyrin 1, erythrocytic
ANPEP alanyl (membrane) aminopeptidase
ANXA7 annexin A7
APOE apolipoprotein E
AR androgen receptor
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARID4A AT rich interactive domain 4A (RBP1-like)
ARID5A AT rich interactive domain 5A (MRF1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4D ADP-ribosylation factor-like 4D
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASL argininosuccinate lyase
ASXL1 additional sex combs like transcriptional regulator 1
ATAD5 ATPase family, AAA domain containing 5
ATM ATM serine/threonine kinase
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP7B ATPase, Cu++ transporting, beta polypeptide
AVPR1A arginine vasopressin receptor 1A
B2M beta-2-microglobulin
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
B9D1 B9 protein domain 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAG1 BCL2-associated athanogene
BAK1 BCL2-antagonist/killer 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BBS5 Bardet-Biedl syndrome 5
BCL10 B-cell CLL/lymphoma 10
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCL6B B-cell CLL/lymphoma 6, member B
BCLAF1 BCL2-associated transcription factor 1
BCR breakpoint cluster region
BGLAP bone gamma-carboxyglutamate (gla) protein
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
BLNK B-cell linker
BMF Bcl2 modifying factor
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BST1 bone marrow stromal cell antigen 1
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C10ORF11 chromosome 10 open reading frame 11
C17ORF62 chromosome 17 open reading frame 62
C1ORF198 chromosome 1 open reading frame 198
C4A complement component 4A (Rodgers blood group)
CADM1 cell adhesion molecule 1
CAMP cathelicidin antimicrobial peptide
CARD11 caspase recruitment domain family, member 11
CARTPT CART prepropeptide
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBFB core-binding factor, beta subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX7 chromobox homolog 7
CCL13 chemokine (C-C motif) ligand 13
CCNB2 cyclin B2
CCND3 cyclin D3
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR9 chemokine (C-C motif) receptor 9
CD19 CD19 molecule
CD200 CD200 molecule
CD22 CD22 molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD300A CD300a molecule
CD36 CD36 molecule (thrombospondin receptor)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD4 CD4 molecule
CD40LG CD40 ligand
CD47 CD47 molecule
CD48 CD48 molecule
CD5 CD5 molecule
CD59 CD59 molecule, complement regulatory protein
CD69 CD69 molecule
CD7 CD7 molecule
CD72 CD72 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD8A CD8a molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CENPJ centromere protein J
CERK ceramide kinase
CHD2 chromodomain helicase DNA binding protein 2
CHD7 chromodomain helicase DNA binding protein 7
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CIITA class II, major histocompatibility complex, transactivator
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CLCN7 chloride channel, voltage-sensitive 7
CLDN18 claudin 18
CLEC10A C-type lectin domain family 10, member A
CLEC2D C-type lectin domain family 2, member D
CLEC4G C-type lectin domain family 4, member G
CLIC1 chloride intracellular channel 1
CLK1 CDC-like kinase 1
CMKLR1 chemerin chemokine-like receptor 1
CNN2 calponin 2
CNOT3 CCR4-NOT transcription complex, subunit 3
COL10A1 collagen, type X, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CORO1A coronin, actin binding protein, 1A
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREBBP CREB binding protein
CRTAM cytotoxic and regulatory T cell molecule
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSE cathepsin E
CTSG cathepsin G
CTSK cathepsin K
CTSV cathepsin V
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYLD cylindromatosis (turban tumor syndrome)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCC DCC netrin 1 receptor
DCK deoxycytidine kinase
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGKA diacylglycerol kinase, alpha 80kDa
DGKZ diacylglycerol kinase, zeta
DIAPH1 diaphanous-related formin 1
DIDO1 death inducer-obliterator 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DMTN dematin actin binding protein
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOK3 docking protein 3
DSG3 desmoglein 3
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP4 dual specificity phosphatase 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F4 E2F transcription factor 4, p107/p130-binding
EBF1 early B-cell factor 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR1 early growth response 1
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
ELF4 E74-like factor 4 (ets domain transcription factor)
ELMO1 engulfment and cell motility 1
ELMOD1 ELMO/CED-12 domain containing 1
EN1 engrailed homeobox 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
EPB42 erythrocyte membrane protein band 4.2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPOR erythropoietin receptor
EPS15 epidermal growth factor receptor pathway substrate 15
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXOC6 exocyst complex component 6
FAHD2B fumarylacetoacetate hydrolase domain containing 2B
FAM104A family with sequence similarity 104, member A
FAM134C family with sequence similarity 134, member C
FAM175B family with sequence similarity 175, member B
FAM83G family with sequence similarity 83, member G
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBLIM1 filamin binding LIM protein 1
FBN1 fibrillin 1
FBXO7 F-box protein 7
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCMR Fc fragment of IgM receptor
FECH ferrochelatase
FES FES proto-oncogene, tyrosine kinase
FFAR2 free fatty acid receptor 2
FGF2 fibroblast growth factor 2 (basic)
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLNA filamin A, alpha
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL2 FOS-like antigen 2
FOXN1 forkhead box N1
FOXO3 forkhead box O3
FOXP2 forkhead box P2
FOXP3 forkhead box P3
FSHR follicle stimulating hormone receptor
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FZD9 frizzled class receptor 9
G6PC3 glucose 6 phosphatase, catalytic, 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GALR2 galanin receptor 2
GAPT GRB2-binding adaptor protein, transmembrane
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GFI1 growth factor independent 1 transcription repressor
GGT1 gamma-glutamyltransferase 1
GHRHR growth hormone releasing hormone receptor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GIMAP6 GTPase, IMAP family member 6
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPI glucose-6-phosphate isomerase
GPR15 G protein-coupled receptor 15
GPR55 G protein-coupled receptor 55
GPR68 G protein-coupled receptor 68
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GSE1 Gse1 coiled-coil protein
GSN gelsolin
HAVCR1 hepatitis A virus cellular receptor 1
HAX1 HCLS1 associated protein X-1
HBA1 hemoglobin, alpha 1
HBP1 HMG-box transcription factor 1
HBZ hemoglobin, zeta
HCK HCK proto-oncogene, Src family tyrosine kinase
HELLS helicase, lymphoid-specific
HK1 hexokinase 1
HLA-A major histocompatibility complex, class I, A
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGB3 high mobility group box 3
HMGN5 high mobility group nucleosome binding domain 5
HP1BP3 heterochromatin protein 1, binding protein 3
HPRT1 hypoxanthine phosphoribosyltransferase 1
HR hair growth associated
HRG histidine-rich glycoprotein
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPG2 heparan sulfate proteoglycan 2
HYAL2 hyaluronoglucosaminidase 2
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDE insulin-degrading enzyme
IER3 immediate early response 3
IFI44 interferon-induced protein 44
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNG interferon, gamma
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL1RL1 interleukin 1 receptor-like 1
IL2 interleukin 2
IL20RB interleukin 20 receptor beta
IL25 interleukin 25
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6ST interleukin 6 signal transducer
IL7R interleukin 7 receptor
IL9R interleukin 9 receptor
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INS insulin
IRAK3 interleukin-1 receptor-associated kinase 3
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
IRS1 insulin receptor substrate 1
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGAD integrin, alpha D
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITK IL2-inducible T-cell kinase
ITPKB inositol-trisphosphate 3-kinase B
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JAM3 junctional adhesion molecule 3
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KDM5A lysine (K)-specific demethylase 5A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF13 Kruppel-like factor 13
KLF15 Kruppel-like factor 15
KLF3 Kruppel-like factor 3 (basic)
KLHL6 kelch-like family member 6
KMT2A lysine (K)-specific methyltransferase 2A
KMT2E lysine (K)-specific methyltransferase 2E
KRAS Kirsten rat sarcoma viral oncogene homolog
LAG3 lymphocyte-activation gene 3
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMA4 laminin, alpha 4
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCAT lecithin-cholesterol acyltransferase
LCN2 lipocalin 2
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDHA lactate dehydrogenase A
LDLR low density lipoprotein receptor
LECT2 leukocyte cell-derived chemotaxin 2
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9B lectin, galactoside-binding, soluble, 9B
LGMN legumain
LIF leukemia inhibitory factor
LIFR leukemia inhibitory factor receptor alpha
LIG1 ligase I, DNA, ATP-dependent
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIMK2 LIM domain kinase 2
LITAF lipopolysaccharide-induced TNF factor
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LRRK1 leucine-rich repeat kinase 1
LSP1 lymphocyte-specific protein 1
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LYN LYN proto-oncogene, Src family tyrosine kinase
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAML1 mastermind-like 1 (Drosophila)
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARC2 mitochondrial amidoxime reducing component 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MAVS mitochondrial antiviral signaling protein
MCM4 minichromosome maintenance complex component 4
MCPH1 microcephalin 1
MDM4 MDM4, p53 regulator
MECOM MDS1 and EVI1 complex locus
MED18 mediator complex subunit 18
MEFV Mediterranean fever
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MIER1 mesoderm induction early response 1, transcriptional regulator
MIR122 microRNA 122
MIR144 microRNA 144
MIR150 microRNA 150
MIR155 microRNA 155
MIR181D microRNA 181d
MIR223 microRNA 223
MIR451A microRNA 451a
MITF microphthalmia-associated transcription factor
MMP19 matrix metallopeptidase 19
MMP9 matrix metallopeptidase 9
MPG N-methylpurine-DNA glycosylase
MPI mannose phosphate isomerase
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MPZ myelin protein zero
MPZL2 myelin protein zero-like 2
MRC1 mannose receptor, C type 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MXD1 MAX dimerization protein 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO1E myosin IE
MYO1G myosin IG
MYSM1 Myb-like, SWIRM and MPN domains 1
NBEAL2 neurobeachin-like 2
NCKAP1L NCK-associated protein 1-like
NCOA3 nuclear receptor coactivator 3
NCOR2 nuclear receptor corepressor 2
NCR1 natural cytotoxicity triggering receptor 1
NDFIP1 Nedd4 family interacting protein 1
NDFIP2 Nedd4 family interacting protein 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2 nuclear factor, erythroid 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NGFR nerve growth factor receptor
NKX2-3 NK2 homeobox 3
NLRC3 NLR family, CARD domain containing 3
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NPC1 Niemann-Pick disease, type C1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR3 natriuretic peptide receptor 3
NPY1R neuropeptide Y receptor Y1
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
OED Oregon eye disease
OTUD7B OTU deubiquitinase 7B
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PARP14 poly (ADP-ribose) polymerase family, member 14
PAWR PRKC, apoptosis, WT1, regulator
PAX1 paired box 1
PAX5 paired box 5
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX3 peroxisomal biogenesis factor 3
PF4 platelet factor 4
PFKM phosphofructokinase, muscle
PI16 peptidase inhibitor 16
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PILRA paired immunoglobin-like type 2 receptor alpha
PITX3 paired-like homeodomain 3
PKLR pyruvate kinase, liver and RBC
PKN1 protein kinase N1
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G15 phospholipase A2, group XV
PLA2G2D phospholipase A2, group IID
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PNP purine nucleoside phosphorylase
POLB polymerase (DNA directed), beta
POMT1 protein-O-mannosyltransferase 1
POSTN periostin, osteoblast specific factor
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP5C protein phosphatase 5, catalytic subunit
PRDM16 PR domain containing 16
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRF1 perforin 1 (pore forming protein)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRMT3 protein arginine methyltransferase 3
PROX1 prospero homeobox 1
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PRSS50 protease, serine, 50
PTCH2 patched 2
PTCRA pre T-cell antigen receptor alpha
PTGDR2 prostaglandin D2 receptor 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PTTG1 pituitary tumor-transforming 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD50 RAD50 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RALB v-ral simian leukemia viral oncogene homolog B
RASA3 RAS p21 protein activator 3
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBP1 retinol binding protein 1, cellular
RC3H1 ring finger and CCCH-type domains 1
REG3G regenerating islet-derived 3 gamma
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RGS3 regulator of G-protein signaling 3
RHBDD3 rhomboid domain containing 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOH ras homolog family member H
RIC1 RAB6A GEF complex partner 1
RNASE10 ribonuclease, RNase A family, 10 (non-active)
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RPA1 replication protein A1, 70kDa
RRAS related RAS viral (r-ras) oncogene homolog
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RTBDN retbindin
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
RUVBL2 RuvB-like AAA ATPase 2
RXFP2 relaxin/insulin-like family peptide receptor 2
S1PR1 sphingosine-1-phosphate receptor 1
S1PR2 sphingosine-1-phosphate receptor 2
SAMD9L sterile alpha motif domain containing 9-like
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCARF1 scavenger receptor class F, member 1
SCTR secretin receptor
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEPT8 septin 8
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD1A SET domain containing 1A
SETD5 SET domain containing 5
SETDB1 SET domain, bifurcated 1
SETMAR SET domain and mariner transposase fusion gene
SFTPD surfactant protein D
SGMS1 sphingomyelin synthase 1
SGPL1 sphingosine-1-phosphate lyase 1
SH2B2 SH2B adaptor protein 2
SH2B3 SH2B adaptor protein 3
SH2D1A SH2 domain containing 1A
SH3BP2 SH3-domain binding protein 2
SHARPIN SHANK-associated RH domain interactor
SIAE sialic acid acetylesterase
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC8 sialic acid binding Ig-like lectin 8
SIPA1 signal-induced proliferation-associated 1
SIRT2 sirtuin 2
SIRT7 sirtuin 7
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLX4 SLX4 structure-specific endonuclease subunit
SMAD3 SMAD family member 3
SMAP1 small ArfGAP 1
SMC3 structural maintenance of chromosomes 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMS spermine synthase
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPI1 Spi-1 proto-oncogene
SPINK5 serine peptidase inhibitor, Kazal type 5
SPNS2 spinster homolog 2 (Drosophila)
SPP1 secreted phosphoprotein 1
SPRED1 sprouty-related, EVH1 domain containing 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SQSTM1 sequestosome 1
SSBP2 single-stranded DNA binding protein 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STEAP3 STEAP family member 3, metalloreductase
STEAP4 STEAP family member 4
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
SUMF1 sulfatase modifying factor 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYK spleen tyrosine kinase
SYTL1 synaptotagmin-like 1
T T, brachyury homolog (mouse)
TANK TRAF family member-associated NFKB activator
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBATA thymus, brain and testes associated
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TCF12 transcription factor 12
TCF3 transcription factor 3
TCF4 transcription factor 4
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TESPA1 thymocyte expressed, positive selection associated 1
TET2 tet methylcytosine dioxygenase 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THEMIS thymocyte selection associated
THRB thyroid hormone receptor, beta
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR2 toll-like receptor 2
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLX1 T-cell leukemia homeobox 1
TMC6 transmembrane channel-like 6
TMEM127 transmembrane protein 127
TMEM189 transmembrane protein 189
TMEM98 transmembrane protein 98
TMUB1 transmembrane and ubiquitin-like domain containing 1
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1
TOB2 transducer of ERBB2, 2
TOM1L2 target of myb1-like 2 (chicken)
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TP53BP1 tumor protein p53 binding protein 1
TPMT thiopurine S-methyltransferase
TPP2 tripeptidyl peptidase II
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3IP2 TRAF3 interacting protein 2
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSPAN33 tetraspanin 33
TSTA3 tissue specific transplantation antigen P35B
TTC7A tetratricopeptide repeat domain 7A
TTLL1 tubulin tyrosine ligase-like family member 1
TUSC2 tumor suppressor candidate 2
TWF1 twinfilin actin binding protein 1
TWSG1 twisted gastrulation BMP signaling modulator 1
TXNIP thioredoxin interacting protein
TYROBP TYRO protein tyrosine kinase binding protein
UBE2B ubiquitin-conjugating enzyme E2B
ULK1 unc-51 like autophagy activating kinase 1
UNC13D unc-13 homolog D (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
URI1 URI1, prefoldin-like chaperone
UROS uroporphyrinogen III synthase
USP21 ubiquitin specific peptidase 21
USP25 ubiquitin specific peptidase 25
USP42 ubiquitin specific peptidase 42
VAV1 vav 1 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VCP valosin containing protein
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPREB1 pre-B lymphocyte 1
VTCN1 V-set domain containing T cell activation inhibitor 1
WAS Wiskott-Aldrich syndrome
WDR1 WD repeat domain 1
WDR37 WD repeat domain 37
WDTC1 WD and tetratricopeptide repeats 1
WTAP Wilms tumor 1 associated protein
XBP1 X-box binding protein 1
XCL1 chemokine (C motif) ligand 1
XPA xeroderma pigmentosum, complementation group A
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1
ZBTB46 zinc finger and BTB domain containing 46
ZBTB7B zinc finger and BTB domain containing 7B
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H12D zinc finger CCCH-type containing 12D
ZDHHC13 zinc finger, DHHC-type containing 13
ZEB1 zinc finger E-box binding homeobox 1
ZFP36 ZFP36 ring finger protein
ZFPM1 zinc finger protein, FOG family member 1
ZNF175 zinc finger protein 175
ZNF205 zinc finger protein 205
ZNF318 zinc finger protein 318
ZP1 zona pellucida glycoprotein 1 (sperm receptor)