increased food intake Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the total number of calories/food amount taken in over time when compared to the normal state (Mammalian Phenotype Ontology, MP_0011939)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011939
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Genes

119 gene mutations causing the increased food intake phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACE angiotensin I converting enzyme
ACOT11 acyl-CoA thioesterase 11
ADIPOR2 adiponectin receptor 2
ADRB3 adrenoceptor beta 3
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGRP agouti related neuropeptide
ALMS1 Alstrom syndrome protein 1
ANKRD26 ankyrin repeat domain 26
APOA4 apolipoprotein A-IV
APOC3 apolipoprotein C-III
APOE apolipoprotein E
ARID5B AT rich interactive domain 5B (MRF1-like)
ASIP agouti signaling protein
BBIP1 BBSome interacting protein 1
BBS1 Bardet-Biedl syndrome 1
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BDNF brain-derived neurotrophic factor
BRS3 bombesin-like receptor 3
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C3 complement component 3
C5AR2 complement component 5a receptor 2
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC7 coiled-coil domain containing 7
CCDC80 coiled-coil domain containing 80
CCKBR cholecystokinin B receptor
CDO1 cysteine dioxygenase type 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP19 centrosomal protein 19kDa
CIDEC cell death-inducing DFFA-like effector c
CLPS colipase, pancreatic
CPE carboxypeptidase E
CRTC1 CREB regulated transcription coactivator 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CYB5R4 cytochrome b5 reductase 4
DRD2 dopamine receptor D2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FFAR1 free fatty acid receptor 1
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXA2 forkhead box A2
FTO fat mass and obesity associated
FXYD4 FXYD domain containing ion transport regulator 4
GDF15 growth differentiation factor 15
GFRA2 GDNF family receptor alpha 2
GHR growth hormone receptor
GNAS GNAS complex locus
GPR26 G protein-coupled receptor 26
GPR50 G protein-coupled receptor 50
GUCY2C guanylate cyclase 2C
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HNF1A HNF1 homeobox A
HRH1 histamine receptor H1
HRH3 histamine receptor H3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IL18 interleukin 18
INS insulin
IRS2 insulin receptor substrate 2
LCLAT1 lysocardiolipin acyltransferase 1
LEP leptin
LEPR leptin receptor
LEPROT leptin receptor overlapping transcript
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPE lipase, hormone-sensitive
MARK4 MAP/microtubule affinity-regulating kinase 4
MBOAT4 membrane bound O-acyltransferase domain containing 4
MC4R melanocortin 4 receptor
MCHR1 melanin-concentrating hormone receptor 1
MRAP2 melanocortin 2 receptor accessory protein 2
MSTN myostatin
MYO7A myosin VIIA
NCOR1 nuclear receptor corepressor 1
NHLH2 nescient helix loop helix 2
NMU neuromedin U
NOS2 nitric oxide synthase 2, inducible
NPBWR1 neuropeptides B/W receptor 1
NPY2R neuropeptide Y receptor Y2
NPY5R neuropeptide Y receptor Y5
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTSR1 neurotensin receptor 1 (high affinity)
OSMR oncostatin M receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PANK1 pantothenate kinase 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLIN1 perilipin 1
POMC proopiomelanocortin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRLH prolactin releasing hormone
PYY peptide YY
RAI1 retinoic acid induced 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SAP130 Sin3A-associated protein, 130kDa
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SDC3 syndecan 3
SIM1 single-minded family bHLH transcription factor 1
SIRT1 sirtuin 1
SIRT7 sirtuin 7
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SQSTM1 sequestosome 1
SSFA2 sperm specific antigen 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TMEM27 transmembrane protein 27
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TUB tubby bipartite transcription factor
UMOD uromodulin
UNC5C unc-5 homolog C (C. elegans)
ZEB1 zinc finger E-box binding homeobox 1