increased follicular b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of resting mature B cells with distinct phenotypic characteristics (CD23-positive, CD21-positive) found typically in the B cell follicle region of the spleen and lymph nodes (Mammalian Phenotype Ontology, MP_0008173)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008173
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Genes

14 gene mutations causing the increased follicular b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMF Bcl2 modifying factor
CYLD cylindromatosis (turban tumor syndrome)
FAS Fas cell surface death receptor
HAX1 HCLS1 associated protein X-1
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IRF8 interferon regulatory factor 8
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PARP14 poly (ADP-ribose) polymerase family, member 14
PRKCD protein kinase C, delta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRAF3IP2 TRAF3 interacting protein 2
WAS Wiskott-Aldrich syndrome