increased dendritic cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of a cells of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation (Mammalian Phenotype Ontology, MP_0008126)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008126
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Genes

20 gene mutations causing the increased dendritic cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADA adenosine deaminase
AIRE autoimmune regulator
CX3CR1 chemokine (C-X3-C motif) receptor 1
FOXP3 forkhead box P3
IL10 interleukin 10
IL18 interleukin 18
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
MAVS mitochondrial antiviral signaling protein
MYD88 myeloid differentiation primary response 88
PLA2G2D phospholipase A2, group IID
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RUNX3 runt-related transcription factor 3
TNF tumor necrosis factor
TRAF3IP2 TRAF3 interacting protein 2
TYROBP TYRO protein tyrosine kinase binding protein
XCL1 chemokine (C motif) ligand 1
ZBTB46 zinc finger and BTB domain containing 46