increased circulating gonadotropin level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the normal blood concentration of the peptide hormones that stimulate gonadal functions such as gametogenesis and sex steroid hormone production in the ovary and the testis (Mammalian Phenotype Ontology, MP_0003362)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003362
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Genes

45 gene mutations causing the increased circulating gonadotropin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADRA1B adrenoceptor alpha 1B
ADRM1 adhesion regulating molecule 1
AFP alpha-fetoprotein
AR androgen receptor
BCL2L2 BCL2-like 2
BGLAP bone gamma-carboxyglutamate (gla) protein
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DHH desert hedgehog
DRD2 dopamine receptor D2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FANCL Fanconi anemia, complementation group L
FOXO3 forkhead box O3
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GDF9 growth differentiation factor 9
GHR growth hormone receptor
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR3 G protein-coupled receptor 3
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAMA2 laminin, alpha 2
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX9 LIM homeobox 9
MRC1 mannose receptor, C type 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NPC1 Niemann-Pick disease, type C1
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PGR progesterone receptor
PLK4 polo-like kinase 4
PRLR prolactin receptor
PSEN1 presenilin 1
PTDSS2 phosphatidylserine synthase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SIX5 SIX homeobox 5
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XPA xeroderma pigmentosum, complementation group A