increased brain tumor incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of abnormal rapidly proliferating cells in the brain, usually in the form of a distinct mass, occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0009277)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009277
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Genes

9 gene mutations causing the increased brain tumor incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CDKN2A cyclin-dependent kinase inhibitor 2A
CXCR6 chemokine (C-X-C motif) receptor 6
LIG4 ligase IV, DNA, ATP-dependent
MSH2 mutS homolog 2
PTCH1 patched 1
RB1 retinoblastoma 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
TP53 tumor protein p53