increased bone trabecula number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased number of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force (Mammalian Phenotype Ontology, MP_0010868)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010868
Similar Terms
Downloads & Tools

Genes

31 gene mutations causing the increased bone trabecula number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGTR2 angiotensin II receptor, type 2
APOE apolipoprotein E
CAV1 caveolin 1, caveolae protein, 22kDa
CD68 CD68 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLCN7 chloride channel, voltage-sensitive 7
CSF1 colony stimulating factor 1 (macrophage)
CTSK cathepsin K
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATA1 GATA binding protein 1 (globin transcription factor 1)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
JDP2 Jun dimerization protein 2
LRRK1 leucine-rich repeat kinase 1
NBR1 neighbor of BRCA1 gene 1
NCOR2 nuclear receptor corepressor 2
PDIA3 protein disulfide isomerase family A, member 3
PHOSPHO1 phosphatase, orphan 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRE protein tyrosine phosphatase, receptor type, E
SBNO2 strawberry notch homolog 2 (Drosophila)
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SOST sclerostin
TMEM64 transmembrane protein 64
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TYROBP TYRO protein tyrosine kinase binding protein