increased basophil cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description higher than average number of basophils as measured by the percent of the total number of leukocytes (Mammalian Phenotype Ontology, MP_0002606)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002606
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Genes

5 gene mutations causing the increased basophil cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALOX15 arachidonate 15-lipoxygenase
GPRC5C G protein-coupled receptor, class C, group 5, member C
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LYN LYN proto-oncogene, Src family tyrosine kinase