increased b-2 b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of conventional B cells subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells (Mammalian Phenotype Ontology, MP_0008206)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008206
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Genes

3 gene mutations causing the increased b-2 b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL2L11 BCL2-like 11 (apoptosis facilitator)
PTPRJ protein tyrosine phosphatase, receptor type, J
TLR8 toll-like receptor 8