increased b cell apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the timing or the number of B cells undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0008782)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008782
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Genes

22 gene mutations causing the increased b cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL2 B-cell CLL/lymphoma 2
BLNK B-cell linker
CD22 CD22 molecule
CXCL12 chemokine (C-X-C motif) ligand 12
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAIM Fas apoptotic inhibitory molecule
FNIP1 folliculin interacting protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
PARP14 poly (ADP-ribose) polymerase family, member 14
PELI1 pellino E3 ubiquitin protein ligase 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POU2AF1 POU class 2 associating factor 1
PRKCD protein kinase C, delta
SFN stratifin
SH3BP2 SH3-domain binding protein 2
SMAD7 SMAD family member 7
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYK spleen tyrosine kinase
TERC telomerase RNA component
TLR2 toll-like receptor 2