increased activated t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal numbers of effector T cells (Mammalian Phenotype Ontology, MP_0001829)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001829
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Genes

21 gene mutations causing the increased activated t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CCR6 chemokine (C-C motif) receptor 6
CD274 CD274 molecule
CLEC4G C-type lectin domain family 4, member G
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DUSP10 dual specificity phosphatase 10
FOXP3 forkhead box P3
GRAP2 GRB2-related adaptor protein 2
HAVCR1 hepatitis A virus cellular receptor 1
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL6ST interleukin 6 signal transducer
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAT linker for activation of T cells
NDFIP1 Nedd4 family interacting protein 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP3 NLR family, pyrin domain containing 3
PRF1 perforin 1 (pore forming protein)
RC3H1 ring finger and CCCH-type domains 1
SOCS1 suppressor of cytokine signaling 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa