incidence Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

446 genes co-occuring with the biological term incidence in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ADD1 adducin 1 (alpha)
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGR2 anterior gradient 2
AGTR1 angiotensin II receptor, type 1
AGXT alanine-glyoxylate aminotransferase
AHRR aryl-hydrocarbon receptor repressor
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
AMPD1 adenosine monophosphate deaminase 1
APC adenomatous polyposis coli
APOB apolipoprotein B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMS2 age-related maculopathy susceptibility 2
ASXL1 additional sex combs like transcriptional regulator 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
B2M beta-2-microglobulin
BAG3 BCL2-associated athanogene 3
BAX BCL2-associated X protein
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BHMT betaine--homocysteine S-methyltransferase
BIRC5 baculoviral IAP repeat containing 5
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTD biotinidase
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C9ORF72 chromosome 9 open reading frame 72
CALR calreticulin
CAPN10 calpain 10
CAPNS1 calpain, small subunit 1
CARD11 caspase recruitment domain family, member 11
CASR calcium-sensing receptor
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL25 chemokine (C-C motif) ligand 25
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR9 chemokine (C-C motif) receptor 9
CD14 CD14 molecule
CD163 CD163 molecule
CD19 CD19 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CD86 CD86 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK2 checkpoint kinase 2
CHGA chromogranin A
CHRD chordin
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CMKLR1 chemerin chemokine-like receptor 1
CNR2 cannabinoid receptor 2 (macrophage)
COL7A1 collagen, type VII, alpha 1
COMT catechol-O-methyltransferase
CP ceruloplasmin (ferroxidase)
CPB2 carboxypeptidase B2 (plasma)
CPT1A carnitine palmitoyltransferase 1A (liver)
CRLF2 cytokine receptor-like factor 2
CRP C-reactive protein, pentraxin-related
CST3 cystatin C
CTAG1B cancer/testis antigen 1B
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP21A1P cytochrome P450, family 21, subfamily A, polypeptide 1 pseudogene
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A cytochrome P450, family 3, subfamily A
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DEC1 deleted in esophageal cancer 1
DHCR7 7-dehydrocholesterol reductase
DMD dystrophin
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD2 dopamine receptor D2
DUSP10 dual specificity phosphatase 10
EDNRB endothelin receptor type B
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
EPO erythropoietin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC2 excision repair cross-complementation group 2
ERP29 endoplasmic reticulum protein 29
ESR1 estrogen receptor 1
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FADS1 fatty acid desaturase 1
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGA fibrinogen alpha chain
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FHIT fragile histidine triad
FHL1 four and a half LIM domains 1
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FPR2 formyl peptide receptor 2
FTL ferritin, light polypeptide
GALT galactose-1-phosphate uridylyltransferase
GAST gastrin
GBA glucosidase, beta, acid
GC group-specific component (vitamin D binding protein)
GCK glucokinase (hexokinase 4)
GFI1 growth factor independent 1 transcription repressor
GGT1 gamma-glutamyltransferase 1
GJB2 gap junction protein, beta 2, 26kDa
GJB3 gap junction protein, beta 3, 31kDa
GJB6 gap junction protein, beta 6, 30kDa
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GP6 glycoprotein VI (platelet)
GPR32 G protein-coupled receptor 32
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HBA1 hemoglobin, alpha 1
HBEGF heparin-binding EGF-like growth factor
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HMGB1 high mobility group box 1
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HOTAIR HOX transcript antisense RNA
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSPA8 heat shock 70kDa protein 8
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICOS inducible T-cell co-stimulator
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGFBP1 insulin-like growth factor binding protein 1
IGH immunoglobulin heavy locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL15 interleukin 15
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23R interleukin 23 receptor
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7R interleukin 7 receptor
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
INS insulin
IRS1 insulin receptor substrate 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK2 Janus kinase 2
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
KIFAP3 kinesin-associated protein 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK3 kallikrein-related peptidase 3
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LCAT lecithin-cholesterol acyltransferase
LCN2 lipocalin 2
LCT lactase
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS2 lectin, galactoside-binding, soluble, 2
LIPC lipase, hepatic
LOXL2 lysyl oxidase-like 2
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LTA lymphotoxin alpha
LTBP1 latent transforming growth factor beta binding protein 1
LZTS1 leucine zipper, putative tumor suppressor 1
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR375 microRNA 375
MITF microphthalmia-associated transcription factor
MLH1 mutL homolog 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MNX1 motor neuron and pancreas homeobox 1
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MT-ATP6 ATP synthase F0 subunit 6
MT-ATP8 ATP synthase F0 subunit 8
MT-TL1 tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MTTP microsomal triglyceride transfer protein
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MVK mevalonate kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH9 myosin, heavy chain 9, non-muscle
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NADSYN1 NAD synthetase 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCF1 neutrophil cytosolic factor 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPHP1 nephronophthisis 1 (juvenile)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPPB natriuretic peptide B
NPY1R neuropeptide Y receptor Y1
NQO1 NAD(P)H dehydrogenase, quinone 1
NUP214 nucleoporin 214kDa
OCA2 oculocutaneous albinism II
OGG1 8-oxoguanine DNA glycosylase
OPRM1 opioid receptor, mu 1
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PACRG PARK2 co-regulated
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDX1 pancreatic and duodenal homeobox 1
PEX6 peroxisomal biogenesis factor 6
PGF placental growth factor
PHF8 PHD finger protein 8
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PINK1 PTEN induced putative kinase 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCE1 phospholipase C, epsilon 1
PNPLA3 patatin-like phospholipase domain containing 3
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROCR protein C receptor, endothelial
PROX1 prospero homeobox 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
PYCARD PYD and CARD domain containing
RAD51 RAD51 recombinase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RET ret proto-oncogene
RHCE Rh blood group, CcEe antigens
RHOA ras homolog family member A
RNR1 RNA, ribosomal cluster 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPA1 replication protein A1, 70kDa
RUNX1 runt-related transcription factor 1
RYR1 ryanodine receptor 1 (skeletal)
SBDS Shwachman-Bodian-Diamond syndrome
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDC1 syndecan 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SET SET nuclear proto-oncogene
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SHBG sex hormone-binding globulin
SIPA1 signal-induced proliferation-associated 1
SIRPG signal-regulatory protein gamma
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLX4IP SLX4 interacting protein
SMAD7 SMAD family member 7
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUMO1 small ubiquitin-like modifier 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TFAM transcription factor A, mitochondrial
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TH tyrosine hydroxylase
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TLX3 T-cell leukemia homeobox 3
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNNI3 troponin I type 3 (cardiac)
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP73 tumor protein p73
TPMT thiopurine S-methyltransferase
TRIM27 tripartite motif containing 27
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TXNDC8 thioredoxin domain containing 8 (spermatozoa)
TYMS thymidylate synthetase
U2AF1 U2 small nuclear RNA auxiliary factor 1
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UTS2 urotensin 2
VCP valosin containing protein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIPR1 vasoactive intestinal peptide receptor 1
VIPR2 vasoactive intestinal peptide receptor 2
VKORC1 vitamin K epoxide reductase complex, subunit 1
WFS1 Wolfram syndrome 1 (wolframin)
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3