impaired behavioral response to xenobiotic Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decreased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response (Mammalian Phenotype Ontology, MP_0009747)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009747
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Genes

72 gene mutations causing the impaired behavioral response to xenobiotic phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADCY5 adenylate cyclase 5
ADORA2A adenosine A2a receptor
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
AQP4 aquaporin 4
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CALCB calcitonin-related polypeptide beta
CCKBR cholecystokinin B receptor
CD81 CD81 molecule
CHRM2 cholinergic receptor, muscarinic 2
CHRM5 cholinergic receptor, muscarinic 5
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAO D-amino-acid oxidase
DLG4 discs, large homolog 4 (Drosophila)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GRM5 glutamate receptor, metabotropic 5
HIPK2 homeodomain interacting protein kinase 2
HLTF helicase-like transcription factor
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
KCNK2 potassium channel, two pore domain subfamily K, member 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LRRK2 leucine-rich repeat kinase 2
MCHR1 melanin-concentrating hormone receptor 1
MGLL monoglyceride lipase
NPY1R neuropeptide Y receptor Y1
NR1I2 nuclear receptor subfamily 1, group I, member 2
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PDLIM5 PDZ and LIM domain 5
PLAT plasminogen activator, tissue
PLCL1 phospholipase C-like 1
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKCG protein kinase C, gamma
RGS4 regulator of G-protein signaling 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A10 S100 calcium binding protein A10
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TACR1 tachykinin receptor 1
TAOK2 TAO kinase 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UNC79 unc-79 homolog (C. elegans)
UPP1 uridine phosphorylase 1
WFS1 Wolfram syndrome 1 (wolframin)