immunological synapse formation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. (Gene Ontology, GO_0001771)
External Link http://amigo.geneontology.org/amigo/term/GO:0001771
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Genes

6 genes participating in the immunological synapse formation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
CCL19 chemokine (C-C motif) ligand 19
CCL21 chemokine (C-C motif) ligand 21
DLG1 discs, large homolog 1 (Drosophila)
DOCK2 dedicator of cytokinesis 2
DOCK8 dedicator of cytokinesis 8
PRF1 perforin 1 (pore forming protein)