immunoglobulin complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. (Gene Ontology, GO_0019814)
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Genes

756 proteins co-occuring with the immunoglobulin complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CD79A CD79a molecule, immunoglobulin-associated alpha 4.40645
CD4 CD4 molecule 2.7342
IL4 interleukin 4 2.62341
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.38532
NELFCD negative elongation factor complex member C/D 2.11002
CD40 CD40 molecule, TNF receptor superfamily member 5 2.06777
CD19 CD19 molecule 1.93972
ALB albumin 1.90355
IL2 interleukin 2 1.88901
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.84088
CD40LG CD40 ligand 1.80306
CD5 CD5 molecule 1.7964
IGHV3-30 immunoglobulin heavy variable 3-30 1.74765
IL5 interleukin 5 1.7287
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.70383
IL10 interleukin 10 1.59199
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.57932
FOXP3 forkhead box P3 1.56731
CD86 CD86 molecule 1.55764
CD79B CD79b molecule, immunoglobulin-associated beta 1.51581
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.50622
BCR breakpoint cluster region 1.47853
TSPO translocator protein (18kDa) 1.44968
TNF tumor necrosis factor 1.44234
NBPF10 neuroblastoma breakpoint family, member 10 1.41755
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 1.40578
AICDA activation-induced cytidine deaminase 1.35594
CD22 CD22 molecule 1.35047
RHD Rh blood group, D antigen 1.34065
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.31412
TBX21 T-box 21 1.31142
CD80 CD80 molecule 1.31088
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.30443
CD52 CD52 molecule 1.30443
IGLV7-43 immunoglobulin lambda variable 7-43 1.30014
CD38 CD38 molecule 1.29906
RHCE Rh blood group, CcEe antigens 1.2708
TG thyroglobulin 1.23244
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.21946
TRIAP1 TP53 regulated inhibitor of apoptosis 1 1.20344
TLR9 toll-like receptor 9 1.19726
CD276 CD276 molecule 1.1952
IL2RA interleukin 2 receptor, alpha 1.18697
TGFB1 transforming growth factor, beta 1 1.18286
IGHV3-9 immunoglobulin heavy variable 3-9 1.18132
IGHE immunoglobulin heavy constant epsilon 1.17363
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.17055
ERBB2 erb-b2 receptor tyrosine kinase 2 1.16389
EGFR epidermal growth factor receptor 1.15928
DSG1 desmoglein 1 1.15364
IFNA1 interferon, alpha 1 1.15313
PDC phosducin 1.14392
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.14341
THY1 Thy-1 cell surface antigen 1.12909
PLA2R1 phospholipase A2 receptor 1, 180kDa 1.09696
DSG3 desmoglein 3 1.0934
CD58 CD58 molecule 1.07968
CXCL9 chemokine (C-X-C motif) ligand 9 1.07359
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) 1.07359
PDCL phosducin-like 1.06853
GATA3 GATA binding protein 3 1.06296
C3 complement component 3 1.05387
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker) 1.05387
LYZ lysozyme 1.05236
CD27 CD27 molecule 1.04934
TLR7 toll-like receptor 7 1.04381
EPCAM epithelial cell adhesion molecule 1.03729
IL6 interleukin 6 1.03629
IL1B interleukin 1, beta 1.02929
ICAM1 intercellular adhesion molecule 1 1.02679
CD69 CD69 molecule 1.01883
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.01784
TLR4 toll-like receptor 4 1.01238
BTK Bruton agammaglobulinemia tyrosine kinase 1.01189
EPX eosinophil peroxidase 0.999068
CD72 CD72 molecule 0.975166
B2M beta-2-microglobulin 0.973714
MYD88 myeloid differentiation primary response 88 0.966956
VIT vitrin 0.945907
IGHV4-39 immunoglobulin heavy variable 4-39 0.943059
ERVW-1 endogenous retrovirus group W, member 1 0.936905
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.936432
MOG myelin oligodendrocyte glycoprotein 0.931245
MUSK muscle, skeletal, receptor tyrosine kinase 0.929833
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.928892
CSN1S1 casein alpha s1 0.926543
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.923728
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.922791
TCHH trichohyalin 0.917177
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.915776
CCL11 chemokine (C-C motif) ligand 11 0.909251
HLA-B major histocompatibility complex, class I, B 0.902281
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 0.900426
LGALS7 lectin, galactoside-binding, soluble, 7 0.899036
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.895794
TLR2 toll-like receptor 2 0.887936
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.887474
SH2D1A SH2 domain containing 1A 0.887474
IL21 interleukin 21 0.883321
ZBTB25 zinc finger and BTB domain containing 25 0.88286
ALPPL2 alkaline phosphatase, placental-like 2 0.865367
ALPL alkaline phosphatase, liver/bone/kidney 0.864907
ALPP alkaline phosphatase, placental 0.864907
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.860311
PTPRC protein tyrosine phosphatase, receptor type, C 0.859852
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.856635
F8 coagulation factor VIII, procoagulant component 0.852042
TPO thyroid peroxidase 0.849746
MUC1 mucin 1, cell surface associated 0.848828
MBP myelin basic protein 0.847451
LTF lactotransferrin 0.845155
COL17A1 collagen, type XVII, alpha 1 0.837351
RNASE3 ribonuclease, RNase A family, 3 0.836892
INS insulin 0.822206
IL1A interleukin 1, alpha 0.821746
TRAC T cell receptor alpha constant 0.809359
LYN LYN proto-oncogene, Src family tyrosine kinase 0.8089
HLA-A major histocompatibility complex, class I, A 0.805689
RAG2 recombination activating gene 2 0.800187
CD33 CD33 molecule 0.79927
IGHV5-51 immunoglobulin heavy variable 5-51 0.796979
BCL6 B-cell CLL/lymphoma 6 0.792396
CRP C-reactive protein, pentraxin-related 0.790106
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.782784
TF transferrin 0.78004
LALBA lactalbumin, alpha- 0.775928
GSTA1 glutathione S-transferase alpha 1 0.771363
GSTA3 glutathione S-transferase alpha 3 0.76726
PAX5 paired box 5 0.765893
GSTA2 glutathione S-transferase alpha 2 0.764982
GSTA4 glutathione S-transferase alpha 4 0.764982
TFRC transferrin receptor 0.763617
CD9 CD9 molecule 0.756345
CD180 CD180 molecule 0.754983
HLA-C major histocompatibility complex, class I, C 0.754983
APOH apolipoprotein H (beta-2-glycoprotein I) 0.748641
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.746381
EPGN epithelial mitogen 0.743671
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.736913
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.731524
CD70 CD70 molecule 0.728836
MPO myeloperoxidase 0.721688
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.721242
STAT4 signal transducer and activator of transcription 4 0.720351
GLB1 galactosidase, beta 1 0.713238
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.709693
LRP4 low density lipoprotein receptor-related protein 4 0.709251
PRSS3 protease, serine, 3 0.706156
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.705273
SELL selectin L 0.703949
TSHR thyroid stimulating hormone receptor 0.696905
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.695148
C4A complement component 4A (Rodgers blood group) 0.69427
FANCB Fanconi anemia, complementation group B 0.693832
CD44 CD44 molecule (Indian blood group) 0.690764
KRAS Kirsten rat sarcoma viral oncogene homolog 0.685954
TLR5 toll-like receptor 5 0.685517
IL7 interleukin 7 0.68508
PRTN3 proteinase 3 0.682027
CXCR5 chemokine (C-X-C motif) receptor 5 0.680284
TSLP thymic stromal lymphopoietin 0.679849
CXCR3 chemokine (C-X-C motif) receptor 3 0.679849
CFP complement factor properdin 0.677673
IL18 interleukin 18 0.67463
IL13 interleukin 13 0.671159
CD34 CD34 molecule 0.670292
MST1R macrophage stimulating 1 receptor 0.669425
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.658188
CCL17 chemokine (C-C motif) ligand 17 0.654741
FASLG Fas ligand (TNF superfamily, member 6) 0.651299
IL1RN interleukin 1 receptor antagonist 0.64915
CCL3 chemokine (C-C motif) ligand 3 0.64915
C5AR1 complement component 5a receptor 1 0.648291
CCL2 chemokine (C-C motif) ligand 2 0.644001
SYK spleen tyrosine kinase 0.642715
FLNC filamin C, gamma 0.638005
GYPC glycophorin C (Gerbich blood group) 0.635868
IGHV4-34 immunoglobulin heavy variable 4-34 0.629892
NBPF8 neuroblastoma breakpoint family, member 8 0.629039
CXCL10 chemokine (C-X-C motif) ligand 10 0.626483
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.617133
SRCIN1 SRC kinase signaling inhibitor 1 0.612048
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.608241
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.607818
F9 coagulation factor IX 0.607395
IL17A interleukin 17A 0.604862
NCAM1 neural cell adhesion molecule 1 0.604862
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.593072
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.590973
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.589295
RBP3 retinol binding protein 3, interstitial 0.587618
IFNG interferon, gamma 0.585523
PRF1 perforin 1 (pore forming protein) 0.582594
CCND1 cyclin D1 0.58134
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.566754
CXCL13 chemokine (C-X-C motif) ligand 13 0.565508
LTA lymphotoxin alpha 0.564262
TES testin LIM domain protein 0.564262
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.563432
ONECUT3 one cut homeobox 3 0.561358
HPR haptoglobin-related protein 0.560528
HP haptoglobin 0.5597
F3 coagulation factor III (thromboplastin, tissue factor) 0.557629
FLT3 fms-related tyrosine kinase 3 0.557629
CD59 CD59 molecule, complement regulatory protein 0.557214
IGF1R insulin-like growth factor 1 receptor 0.557214
VCAM1 vascular cell adhesion molecule 1 0.555145
ALK anaplastic lymphoma receptor tyrosine kinase 0.554732
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.552664
CD37 CD37 molecule 0.552251
CD81 CD81 molecule 0.542764
WARS tryptophanyl-tRNA synthetase 0.535772
IGLON5 IgLON family member 5 0.53413
HLA-DOB major histocompatibility complex, class II, DO beta 0.533719
STX1B syntaxin 1B 0.533309
FTH1 ferritin, heavy polypeptide 1 0.532488
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.530028
AOC3 amine oxidase, copper containing 3 0.529618
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.529618
CRNN cornulin 0.528388
PPT2 palmitoyl-protein thioesterase 2 0.527979
C1S complement component 1, s subcomponent 0.527569
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.52225
AFP alpha-fetoprotein 0.521841
POU2AF1 POU class 2 associating factor 1 0.520615
SLURP1 secreted LY6/PLAUR domain containing 1 0.517348
PLA2G1B phospholipase A2, group IB (pancreas) 0.515716
IL15 interleukin 15 0.515308
ABHD8 abhydrolase domain containing 8 0.5149
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 0.5149
SLAMF9 SLAM family member 9 0.5149
TMEM121 transmembrane protein 121 0.5149
EMILIN3 elastin microfibril interfacer 3 0.5149
LPO lactoperoxidase 0.514493
SPINK1 serine peptidase inhibitor, Kazal type 1 0.512862
C8G complement component 8, gamma polypeptide 0.512862
A2M alpha-2-macroglobulin 0.512047
CA2 carbonic anhydrase II 0.51164
DPT dermatopontin 0.511233
IL23A interleukin 23, alpha subunit p19 0.50879
CCL24 chemokine (C-C motif) ligand 24 0.508383
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.50635
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.505944
RAG1 recombination activating gene 1 0.503506
IGHV3-43 immunoglobulin heavy variable 3-43 0.500258
IGKV3-15 immunoglobulin kappa variable 3-15 0.500258
CD6 CD6 molecule 0.49742
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.495395
CCL21 chemokine (C-C motif) ligand 21 0.495395
HBE1 hemoglobin, epsilon 1 0.495395
CCL19 chemokine (C-C motif) ligand 19 0.493775
CD1D CD1d molecule 0.489327
FTL ferritin, light polypeptide 0.487711
VWF von Willebrand factor 0.485289
PBK PDZ binding kinase 0.484483
FDCSP follicular dendritic cell secreted protein 0.483676
IGHV1-2 immunoglobulin heavy variable 1-2 0.480855
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 0.474822
PRDM1 PR domain containing 1, with ZNF domain 0.474018
LCK LCK proto-oncogene, Src family tyrosine kinase 0.472813
IRF4 interferon regulatory factor 4 0.472412
CD68 CD68 molecule 0.472011
MAGEB1 melanoma antigen family B1 0.471609
CCR7 chemokine (C-C motif) receptor 7 0.463997
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.454816
CD2 CD2 molecule 0.454019
IGH immunoglobulin heavy locus 0.452825
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 0.452427
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.449245
VEGFA vascular endothelial growth factor A 0.448451
BLNK B-cell linker 0.448054
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.446862
IGHV1-69 immunoglobulin heavy variable 1-69 0.446862
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.443689
CCL7 chemokine (C-C motif) ligand 7 0.4425
IGHV1-3 immunoglobulin heavy variable 1-3 0.4425
CD200 CD200 molecule 0.4425
EFTUD1 elongation factor Tu GTP binding domain containing 1 0.4425
TLR3 toll-like receptor 3 0.438937
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.437356
SFTPA1 surfactant protein A1 0.43617
STX2 syntaxin 2 0.433801
CCR3 chemokine (C-C motif) receptor 3 0.431435
FN1 fibronectin 1 0.429859
PAX2 paired box 2 0.429072
CCL5 chemokine (C-C motif) ligand 5 0.424745
CTSL cathepsin L 0.42396
PTGDR2 prostaglandin D2 receptor 2 0.42396
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.423174
F12 coagulation factor XII (Hageman factor) 0.421604
B3GAT1 beta-1,3-glucuronyltransferase 1 0.420428
IL9 interleukin 9 0.416902
CD83 CD83 molecule 0.412601
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.410259
CD7 CD7 molecule 0.409479
IGLV2-23 immunoglobulin lambda variable 2-23 0.405971
IGHJ3 immunoglobulin heavy joining 3 0.405971
AKR1E2 aldo-keto reductase family 1, member E2 0.405971
FCRL5 Fc receptor-like 5 0.403637
MRC1 mannose receptor, C type 1 0.401693
TMEM133 transmembrane protein 133 0.401693
TREML2 triggering receptor expressed on myeloid cells-like 2 0.400139
KLK3 kallikrein-related peptidase 3 0.399751
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.399363
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.393549
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.392775
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.392388
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.388909
COL7A1 collagen, type VII, alpha 1 0.386208
PIGR polymeric immunoglobulin receptor 0.386208
HDAC7 histone deacetylase 7 0.385822
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.385051
NANP N-acetylneuraminic acid phosphatase 0.385051
IGHA1 immunoglobulin heavy constant alpha 1 0.384665
IFNB1 interferon, beta 1, fibroblast 0.38428
IL31 interleukin 31 0.380814
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.380429
ARG1 arginase 1 0.378122
APOE apolipoprotein E 0.368153
IL27RA interleukin 27 receptor, alpha 0.367388
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 0.367006
IGIP IgA-inducing protein 0.364331
PREB prolactin regulatory element binding 0.364331
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.360896
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.360133
LAG3 lymphocyte-activation gene 3 0.359371
SAG S-antigen; retina and pineal gland (arrestin) 0.35899
HLA-E major histocompatibility complex, class I, E 0.358228
HMGA2 high mobility group AT-hook 2 0.355944
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.352901
WFDC2 WAP four-disulfide core domain 2 0.352522
IL3 interleukin 3 0.352142
HRAS Harvey rat sarcoma viral oncogene homolog 0.350243
NCR3 natural cytotoxicity triggering receptor 3 0.350243
HTRA1 HtrA serine peptidase 1 0.348725
SCRN3 secernin 3 0.348346
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.347967
IL1R1 interleukin 1 receptor, type I 0.346071
CD247 CD247 molecule 0.343421
PTBP2 polypyrimidine tract binding protein 2 0.342285
TAGLN transgelin 0.342285
CD200R1 CD200 receptor 1 0.341151
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.340017
DNTT DNA nucleotidylexotransferase 0.339261
F2 coagulation factor II (thrombin) 0.337751
GGT1 gamma-glutamyltransferase 1 0.337373
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.336241
TRIM46 tripartite motif containing 46 0.336241
SELE selectin E 0.335864
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.335487
SOS1 son of sevenless homolog 1 (Drosophila) 0.333979
FER fer (fps/fes related) tyrosine kinase 0.333225
STX1A syntaxin 1A (brain) 0.331342
LATS1 large tumor suppressor kinase 1 0.331342
MUC3A mucin 3A, cell surface associated 0.330966
CTSG cathepsin G 0.326078
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.323825
EIF3A eukaryotic translation initiation factor 3, subunit A 0.323075
EPHA2 EPH receptor A2 0.32195
ACPP acid phosphatase, prostate 0.32195
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.321575
CXCL8 chemokine (C-X-C motif) ligand 8 0.320451
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.318579
TRO trophinin 0.317082
ZNF296 zinc finger protein 296 0.316708
CD63 CD63 molecule 0.31596
OAT ornithine aminotransferase 0.314091
IL4R interleukin 4 receptor 0.313344
MDK midkine (neurite growth-promoting factor 2) 0.311851
CT45A1 cancer/testis antigen family 45, member A1 0.311851
CFB complement factor B 0.310732
CD96 CD96 molecule 0.309986
KRTAP1-3 keratin associated protein 1-3 0.308494
TRIM21 tripartite motif containing 21 0.30626
YBX2 Y box binding protein 2 0.30626
CSF3 colony stimulating factor 3 (granulocyte) 0.301425
IL25 interleukin 25 0.29994
SELPLG selectin P ligand 0.299197
IRF5 interferon regulatory factor 5 0.296972
HIST2H2AC histone cluster 2, H2ac 0.29623
HIST2H2AA3 histone cluster 2, H2aa3 0.29586
HIST2H2AA4 histone cluster 2, H2aa4 0.29586
PRSS1 protease, serine, 1 (trypsin 1) 0.294748
PF4 platelet factor 4 0.294748
TOX thymocyte selection-associated high mobility group box 0.294748
HSPA4 heat shock 70kDa protein 4 0.294378
FLT1 fms-related tyrosine kinase 1 0.294378
NOD2 nucleotide-binding oligomerization domain containing 2 0.294378
POMC proopiomelanocortin 0.292897
FOLR2 folate receptor 2 (fetal) 0.291787
CD24 CD24 molecule 0.291417
AQP4 aquaporin 4 0.290678
FCMR Fc fragment of IgM receptor 0.290678
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.290678
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.289938
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.285507
TSPAN3 tetraspanin 3 0.285138
CD48 CD48 molecule 0.281453
CENPV centromere protein V 0.279612
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.279612
IL6R interleukin 6 receptor 0.279612
ICOSLG inducible T-cell co-stimulator ligand 0.279245
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 0.278509
MRAP melanocortin 2 receptor accessory protein 0.278141
ASPN asporin 0.277774
BCAS3 breast carcinoma amplified sequence 3 0.277774
ADRB1 adrenoceptor beta 1 0.277038
PIDD1 p53-induced death domain protein 1 0.275936
MUC2 mucin 2, oligomeric mucus/gel-forming 0.274468
ZNF85 zinc finger protein 85 0.273
SDC1 syndecan 1 0.272633
ZNRD1 zinc ribbon domain containing 1 0.272267
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.271533
TGFB2 transforming growth factor, beta 2 0.271533
BLK BLK proto-oncogene, Src family tyrosine kinase 0.271167
NPB neuropeptide B 0.2708
FYN FYN proto-oncogene, Src family tyrosine kinase 0.270434
CP ceruloplasmin (ferroxidase) 0.268603
NEU2 sialidase 2 (cytosolic sialidase) 0.268603
MTSS1 metastasis suppressor 1 0.268237
NGF nerve growth factor (beta polypeptide) 0.267871
KRTAP1-1 keratin associated protein 1-1 0.267871
HHAT hedgehog acyltransferase 0.267139
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.266774
CCL13 chemokine (C-C motif) ligand 13 0.265311
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.26166
CD248 CD248 molecule, endosialin 0.259837
DHFR dihydrofolate reductase 0.257289
KNTC1 kinetochore associated 1 0.253653
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.253653
CD8A CD8a molecule 0.249302
SRRM1 serine/arginine repetitive matrix 1 0.246769
CD1E CD1e molecule 0.246407
PVR poliovirus receptor 0.244962
MUC16 mucin 16, cell surface associated 0.241716
KNG1 kininogen 1 0.240996
IGHJ6 immunoglobulin heavy joining 6 0.239916
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.238478
STAP2 signal transducing adaptor family member 2 0.238478
CDSN corneodesmosin 0.237401
PTPRD protein tyrosine phosphatase, receptor type, D 0.237042
PLG plasminogen 0.236683
F5 coagulation factor V (proaccelerin, labile factor) 0.236324
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.236324
ICK intestinal cell (MAK-like) kinase 0.235966
CPA6 carboxypeptidase A6 0.234891
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.234891
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.232744
TP53 tumor protein p53 0.232386
DAND5 DAN domain family member 5, BMP antagonist 0.231315
MBL2 mannose-binding lectin (protein C) 2, soluble 0.230601
LY96 lymphocyte antigen 96 0.230601
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.228108
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene 0.227752
DCXR dicarbonyl/L-xylulose reductase 0.227397
GIF gastric intrinsic factor (vitamin B synthesis) 0.224913
CCR8 chemokine (C-C motif) receptor 8 0.224204
ICAM3 intercellular adhesion molecule 3 0.22385
REV1 REV1, polymerase (DNA directed) 0.221378
DHDH dihydrodiol dehydrogenase (dimeric) 0.219969
AIRE autoimmune regulator 0.219969
MRPL12 mitochondrial ribosomal protein L12 0.218914
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.217861
SFTPA2 surfactant protein A2 0.217861
XBP1 X-box binding protein 1 0.217511
GPR176 G protein-coupled receptor 176 0.21716
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.21716
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.21716
IL17RA interleukin 17 receptor A 0.21681
HSH2D hematopoietic SH2 domain containing 0.21646
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.21646
THPO thrombopoietin 0.216111
CD8BP CD8b molecule pseudogene 0.215412
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.215412
LAT linker for activation of T cells 0.213669
IFNA6 interferon, alpha 6 0.212627
HRH2 histamine receptor H2 0.21228
ADRB2 adrenoceptor beta 2, surface 0.21228
VSTM1 V-set and transmembrane domain containing 1 0.211587
IL7R interleukin 7 receptor 0.211587
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.210549
KITLG KIT ligand 0.210203
PLAT plasminogen activator, tissue 0.209858
TPT1 tumor protein, translationally-controlled 1 0.209858
IGHM immunoglobulin heavy constant mu 0.209169
HDAC11 histone deacetylase 11 0.208825
SYT12 synaptotagmin XII 0.208481
ACE angiotensin I converting enzyme 0.207794
CXCL12 chemokine (C-X-C motif) ligand 12 0.206082
AGPS alkylglycerone phosphate synthase 0.205059
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.203022
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.201672
IFNA2 interferon, alpha 2 0.200999
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.200328
ITLN2 intelectin 2 0.198325
AKAP17A A kinase (PRKA) anchor protein 17A 0.196669
EPHB4 EPH receptor B4 0.19601
IPP intracisternal A particle-promoted polypeptide 0.195353
CCL8 chemokine (C-C motif) ligand 8 0.195353
TLR1 toll-like receptor 1 0.194698
GAST gastrin 0.193719
APP amyloid beta (A4) precursor protein 0.193394
CD14 CD14 molecule 0.192746
ELANE elastase, neutrophil expressed 0.191135
SFTPD surfactant protein D 0.191135
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.190814
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.190814
POLQ polymerase (DNA directed), theta 0.189539
IL17RB interleukin 17 receptor B 0.189222
HSPG2 heparan sulfate proteoglycan 2 0.18702
ADGRG6 adhesion G protein-coupled receptor G6 0.186087
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.185469
MMP10 matrix metallopeptidase 10 0.184853
ENO1 enolase 1, (alpha) 0.183935
ING1 inhibitor of growth family, member 1 0.182422
PHF11 PHD finger protein 11 0.182422
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.182122
CPB1 carboxypeptidase B1 (tissue) 0.180634
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.180634
CCR9 chemokine (C-C motif) receptor 9 0.180634
FOS FBJ murine osteosarcoma viral oncogene homolog 0.180634
ERBB3 erb-b2 receptor tyrosine kinase 3 0.180045
CD226 CD226 molecule 0.180045
PFN2 profilin 2 0.179459
ENG endoglin 0.179167
CCL1 chemokine (C-C motif) ligand 1 0.178588
DLL1 delta-like 1 (Drosophila) 0.177154
MSLN mesothelin 0.17687
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 0.175466
IFNA5 interferon, alpha 5 0.175188
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 0.174911
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.174635
LTB lymphotoxin beta (TNF superfamily, member 3) 0.174361
STAT1 signal transducer and activator of transcription 1, 91kDa 0.174361
CARS cysteinyl-tRNA synthetase 0.174361
LGALS3 lectin, galactoside-binding, soluble, 3 0.174361
RB1 retinoblastoma 1 0.173543
PRNP prion protein 0.172201
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.171937
ZNF77 zinc finger protein 77 0.17141
FBXO8 F-box protein 8 0.170888
C4B complement component 4B (Chido blood group) 0.170888
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.169859
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.169099
RGMA repulsive guidance molecule family member a 0.169099
DMBT1 deleted in malignant brain tumors 1 0.168847
IFNGR1 interferon gamma receptor 1 0.168349
CD46 CD46 molecule, complement regulatory protein 0.167611
ACE2 angiotensin I converting enzyme 2 0.167366
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.167366
JCHAIN joining chain of multimeric IgA and IgM 0.167125
BCAP29 B-cell receptor-associated protein 29 0.166405
HADH hydroxyacyl-CoA dehydrogenase 0.166405
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.165932
CAMKV CaM kinase-like vesicle-associated 0.164542
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.163865
TROVE2 TROVE domain family, member 2 0.163641
TPI1 triosephosphate isomerase 1 0.163641
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.16342
PDPN podoplanin 0.162763
SIGLEC14 sialic acid binding Ig-like lectin 14 0.16233
PMEL premelanosome protein 0.161484
SST somatostatin 0.161068
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.160053
GYPA glycophorin A (MNS blood group) 0.159658
IL22 interleukin 22 0.158502
TWSG1 twisted gastrulation BMP signaling modulator 1 0.157578
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.157578
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 0.138304
SIGLEC10 sialic acid binding Ig-like lectin 10 0.133289
CCL25 chemokine (C-C motif) ligand 25 0.132145
ZBTB48 zinc finger and BTB domain containing 48 0.129269
ADAMDEC1 ADAM-like, decysin 1 0.12787
CCDC112 coiled-coil domain containing 112 0.127845
SPIC Spi-C transcription factor (Spi-1/PU.1 related) 0.127237
C1GALT1C1 C1GALT1-specific chaperone 1 0.126833
EGR1 early growth response 1 0.126419
SPPL2A signal peptide peptidase like 2A 0.123689
NUB1 negative regulator of ubiquitin-like proteins 1 0.122688
SPN sialophorin 0.122078
TREML1 triggering receptor expressed on myeloid cells-like 1 0.121946
TNP1 transition protein 1 (during histone to protamine replacement) 0.120755
SLA Src-like-adaptor 0.120667
MLN motilin 0.120481
CCND2 cyclin D2 0.120247
RAET1E retinoic acid early transcript 1E 0.120142
CLC Charcot-Leyden crystal galectin 0.119823
ZFP36L1 ZFP36 ring finger protein-like 1 0.118985
HDX highly divergent homeobox 0.118457
PLVAP plasmalemma vesicle associated protein 0.117233
ZDHHC23 zinc finger, DHHC-type containing 23 0.116361
IL33 interleukin 33 0.116016
CD93 CD93 molecule 0.115999
FGR FGR proto-oncogene, Src family tyrosine kinase 0.11555
ADORA3 adenosine A3 receptor 0.114561
CMA1 chymase 1, mast cell 0.113923
KRT84 keratin 84, type II 0.113876
PGM3 phosphoglucomutase 3 0.113314
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.112967
PHAX phosphorylated adaptor for RNA export 0.112606
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.111818
PRKCH protein kinase C, eta 0.111447
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.111166
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.111112
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.110971
CD209 CD209 molecule 0.110717
BCAP31 B-cell receptor-associated protein 31 0.110429
NPTN neuroplastin 0.10776
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.106174
MERTK MER proto-oncogene, tyrosine kinase 0.105173
FBF1 Fas (TNFRSF6) binding factor 1 0.105104
BCL2L1 BCL2-like 1 0.105008
MTDH metadherin 0.10408
EMC3 ER membrane protein complex subunit 3 0.100373
DCT dopachrome tautomerase 0.099362
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.098013
TMEM11 transmembrane protein 11 0.097664
CD1C CD1c molecule 0.097128
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 0.096175
TOE1 target of EGR1, member 1 (nuclear) 0.095848
CCNG2 cyclin G2 0.095727
SMAD5-AS1 SMAD5 antisense RNA 1 0.095413
CA1 carbonic anhydrase I 0.094425
RXRA retinoid X receptor, alpha 0.09396
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.093889
BET1 Bet1 golgi vesicular membrane trafficking protein 0.093799
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.093563
SPAG9 sperm associated antigen 9 0.093545
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.092999
PHYH phytanoyl-CoA 2-hydroxylase 0.091742
CCR2 chemokine (C-C motif) receptor 2 0.091102
DUSP5 dual specificity phosphatase 5 0.090647
SELENBP1 selenium binding protein 1 0.090436
TMPO thymopoietin 0.089726
CDH9 cadherin 9, type 2 (T1-cadherin) 0.089668
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.08924
HM13 histocompatibility (minor) 13 0.089182
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.089143
MX2 MX dynamin-like GTPase 2 0.088891
CNTF ciliary neurotrophic factor 0.08822
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.088161
BCL2 B-cell CLL/lymphoma 2 0.087446
GCLC glutamate-cysteine ligase, catalytic subunit 0.087005
TECR trans-2,3-enoyl-CoA reductase 0.086785
TRIM37 tripartite motif containing 37 0.085912
NEUROD1 neuronal differentiation 1 0.085544
MEOX1 mesenchyme homeobox 1 0.084988
TCN2 transcobalamin II 0.0847
CIAO1 cytosolic iron-sulfur assembly component 1 0.084075
RGS1 regulator of G-protein signaling 1 0.083237
EBF1 early B-cell factor 1 0.082794
AKAP4 A kinase (PRKA) anchor protein 4 0.082773
TUBE1 tubulin, epsilon 1 0.081644
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.081129
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.080113
MARS methionyl-tRNA synthetase 0.079938
CA5A carbonic anhydrase VA, mitochondrial 0.079282
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.07891
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.078468
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.078247
CD8B CD8b molecule 0.077292
TFEB transcription factor EB 0.07727
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.076981
ICOS inducible T-cell co-stimulator 0.076914
CA5B carbonic anhydrase VB, mitochondrial 0.076914
STAB1 stabilin 1 0.076825
SEPT4 septin 4 0.076286
PRMT2 protein arginine methyltransferase 2 0.076016
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.075657
JAK3 Janus kinase 3 0.075408
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.075113
CA8 carbonic anhydrase VIII 0.074773
CA14 carbonic anhydrase XIV 0.07475
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.074569
DYNLT1 dynein, light chain, Tctex-type 1 0.074022
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.073908
CA6 carbonic anhydrase VI 0.073885
CA7 carbonic anhydrase VII 0.073816
HSPE1 heat shock 10kDa protein 1 0.073497
APRT adenine phosphoribosyltransferase 0.073382
FOXD3 forkhead box D3 0.073085
PDE9A phosphodiesterase 9A 0.072854
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.072417
MX1 MX dynamin-like GTPase 1 0.072233
BCAM basal cell adhesion molecule (Lutheran blood group) 0.072141
CA13 carbonic anhydrase XIII 0.071911
SATB1 SATB homeobox 1 0.071725
CA12 carbonic anhydrase XII 0.071609
CHL1 cell adhesion molecule L1-like 0.071146
KLK6 kallikrein-related peptidase 6 0.070984
ADAM15 ADAM metallopeptidase domain 15 0.070961
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.070845
MFGE8 milk fat globule-EGF factor 8 protein 0.070636
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.070216
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.069867
NT5C1A 5'-nucleotidase, cytosolic IA 0.069844
MICB MHC class I polypeptide-related sequence B 0.06982
IFNA17 interferon, alpha 17 0.068885
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.068861
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.068393
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.067687
NRG1 neuregulin 1 0.067499
ADAM2 ADAM metallopeptidase domain 2 0.066887
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.06665
MRO maestro 0.066367
PNLIP pancreatic lipase 0.066343
CDK6 cyclin-dependent kinase 6 0.065989
CA3 carbonic anhydrase III 0.0658
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.065468
MEF2C myocyte enhancer factor 2C 0.065278
ITPKB inositol-trisphosphate 3-kinase B 0.065017
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.064804
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.064662
TCL1A T-cell leukemia/lymphoma 1A 0.064638
CLPS colipase, pancreatic 0.064615
KDR kinase insert domain receptor 0.064615
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.064615
JRK Jrk homolog (mouse) 0.064591
HLA-DMA major histocompatibility complex, class II, DM alpha 0.064591
POLM polymerase (DNA directed), mu 0.064567
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.064543
L1CAM L1 cell adhesion molecule 0.064519
VIL1 villin 1 0.064496
PNMA2 paraneoplastic Ma antigen 2 0.064448
CRLF2 cytokine receptor-like factor 2 0.064353
HOPX HOP homeobox 0.064305
HDAC4 histone deacetylase 4 0.064305
IFT122 intraflagellar transport 122 0.064305
ZNF146 zinc finger protein 146 0.064305
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.064305
ITGB7 integrin, beta 7 0.064282
CUL3 cullin 3 0.064234
CCNG1 cyclin G1 0.064186
ABHD2 abhydrolase domain containing 2 0.064139
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.064068
CA9 carbonic anhydrase IX 0.064068
ENGASE endo-beta-N-acetylglucosaminidase 0.063901
PDZD2 PDZ domain containing 2 0.063877
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.063782
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.063782
CCL20 chemokine (C-C motif) ligand 20 0.063759
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.063759
UNK unkempt family zinc finger 0.063616
GPA33 glycoprotein A33 (transmembrane) 0.063592
MYH9 myosin, heavy chain 9, non-muscle 0.063592
ZFPM1 zinc finger protein, FOG family member 1 0.063474
RPS19 ribosomal protein S19 0.06345
IL1RAP interleukin 1 receptor accessory protein 0.063426
THBS3 thrombospondin 3 0.063426
ARHGAP26 Rho GTPase activating protein 26 0.063403
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 0.063355
KPTN kaptin (actin binding protein) 0.063331
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.063331
IGBP1 immunoglobulin (CD79A) binding protein 1 0.063283
IL17RD interleukin 17 receptor D 0.063164
TXN thioredoxin 0.063116