ifosfamide-6279 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ifosfamide-6279 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAM8 ADAM metallopeptidase domain 8
ALS2CL ALS2 C-terminal like
APOL6 apolipoprotein L, 6
APP amyloid beta (A4) precursor protein
ARL4C ADP-ribosylation factor-like 4C
ARRB1 arrestin, beta 1
BMP4 bone morphogenetic protein 4
CAMK1 calcium/calmodulin-dependent protein kinase I
CD3D CD3d molecule, delta (CD3-TCR complex)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP104 centrosomal protein 104kDa
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLSTN2 calsyntenin 2
CLUAP1 clusterin associated protein 1
CUZD1 CUB and zona pellucida-like domains 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAGLA diacylglycerol lipase, alpha
DAPK2 death-associated protein kinase 2
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DOCK5 dedicator of cytokinesis 5
DSCAM Down syndrome cell adhesion molecule
EDNRA endothelin receptor type A
EMID1 EMI domain containing 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERCC5 excision repair cross-complementation group 5
FAM118A family with sequence similarity 118, member A
FAM212B family with sequence similarity 212, member B
FOXJ3 forkhead box J3
FZD7 frizzled class receptor 7
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPR31 G protein-coupled receptor 31
HIST1H3A histone cluster 1, H3a
IDI2-AS1 IDI2 antisense RNA 1
IFT140 intraflagellar transport 140
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0754 KIAA0754
KIAA1109 KIAA1109
KLK5 kallikrein-related peptidase 5
KRT17 keratin 17, type I
LIMK2 LIM domain kinase 2
LPPR2 lipid phosphate phosphatase-related protein type 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP4 microtubule-associated protein 4
MED16 mediator complex subunit 16
MYH14 myosin, heavy chain 14, non-muscle
NEK9 NIMA-related kinase 9
NEURL1 neuralized E3 ubiquitin protein ligase 1
NTS neurotensin
PARVA parvin, alpha
PDGFD platelet derived growth factor D
PER3 period circadian clock 3
PLXNA1 plexin A1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLG polymerase (DNA directed), gamma
PRDX2 peroxiredoxin 2
PSPH phosphoserine phosphatase
PTGIS prostaglandin I2 (prostacyclin) synthase
RARG retinoic acid receptor, gamma
ROM1 retinal outer segment membrane protein 1
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BP2 SH3-domain binding protein 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMC1A structural maintenance of chromosomes 1A
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SPPL2B signal peptide peptidase like 2B
ST7L suppression of tumorigenicity 7 like
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUGP1 SURP and G patch domain containing 1
SUN1 Sad1 and UNC84 domain containing 1
TAGLN3 transgelin 3
TESC tescalcin
TIMELESS timeless circadian clock
TLE4 transducin-like enhancer of split 4
TRD T cell receptor delta locus
TREX1 three prime repair exonuclease 1
TTBK2 tau tubulin kinase 2
UBE3A ubiquitin protein ligase E3A
UBOX5 U-box domain containing 5
WIZ widely interspaced zinc finger motifs
WNT2B wingless-type MMTV integration site family, member 2B
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADGRE5 adhesion G protein-coupled receptor E5
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP10 Rho GTPase activating protein 10
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATAD5 ATPase family, AAA domain containing 5
C10ORF88 chromosome 10 open reading frame 88
CALCOCO1 calcium binding and coiled-coil domain 1
CENPJ centromere protein J
CENPT centromere protein T
CEP131 centrosomal protein 131kDa
CEP72 centrosomal protein 72kDa
CFD complement factor D (adipsin)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLK2 CDC-like kinase 2
COPS7B COP9 signalosome subunit 7B
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
EDC3 enhancer of mRNA decapping 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERO1L ERO1-like (S. cerevisiae)
EVPL envoplakin
F8 coagulation factor VIII, procoagulant component
FAM155B family with sequence similarity 155, member B
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
FPGS folylpolyglutamate synthase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPRC5C G protein-coupled receptor, class C, group 5, member C
HIRA histone cell cycle regulator
HOOK1 hook microtubule-tethering protein 1
HYOU1 hypoxia up-regulated 1
IFT46 intraflagellar transport 46
IFT81 intraflagellar transport 81
IMPACT impact RWD domain protein
KAT2A K(lysine) acetyltransferase 2A
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0895 KIAA0895
KIZ kizuna centrosomal protein
LRRC20 leucine rich repeat containing 20
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEF1 melanoma antigen family F1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBIP MAP3K12 binding inhibitory protein 1
MICALL2 MICAL-like 2
MNX1 motor neuron and pancreas homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFSD methenyltetrahydrofolate synthetase domain containing
MUS81 MUS81 structure-specific endonuclease subunit
MYO19 myosin XIX
NDE1 nudE neurodevelopment protein 1
NUPL2 nucleoporin like 2
NVL nuclear VCP-like
OSMR oncostatin M receptor
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARD6A par-6 family cell polarity regulator alpha
PARP12 poly (ADP-ribose) polymerase family, member 12
PLA2G15 phospholipase A2, group XV
POMT2 protein-O-mannosyltransferase 2
PPAN peter pan homolog (Drosophila)
PYCRL pyrroline-5-carboxylate reductase-like
RBM38 RNA binding motif protein 38
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RGS19 regulator of G-protein signaling 19
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL23AP7 ribosomal protein L23a pseudogene 7
SAV1 salvador family WW domain containing protein 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SECTM1 secreted and transmembrane 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SH2D4A SH2 domain containing 4A
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
STBD1 starch binding domain 1
SUSD6 sushi domain containing 6
SYNGR3 synaptogyrin 3
TESK2 testis-specific kinase 2
TMEM104 transmembrane protein 104
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TPST2 tyrosylprotein sulfotransferase 2
TTC23 tetratricopeptide repeat domain 23
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ULBP2 UL16 binding protein 2
VGF VGF nerve growth factor inducible
WDR19 WD repeat domain 19
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF331 zinc finger protein 331
ZNF747 zinc finger protein 747
ZNF770 zinc finger protein 770
ZSCAN31 zinc finger and SCAN domain containing 31
ZXDC ZXD family zinc finger C