hyperthyroidism Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A thyroid gland disease that involves an over production of thyroid hormone. (Human Disease Ontology, DOID_7998)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0000836
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Genes

45 genes associated with the hyperthyroidism phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
TSHR thyroid stimulating hormone receptor 2.07915
C6ORF10 chromosome 6 open reading frame 10 2.0492
C1QTNF6 C1q and tumor necrosis factor related protein 6 1.94848
SLAMF6 SLAM family member 6 1.88591
HLA-J major histocompatibility complex, class I, J (pseudogene) 1.74205
TCF19 transcription factor 19 1.68604
CCHCR1 coiled-coil alpha-helical rod protein 1 1.65651
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.63258
MUC22 mucin 22 1.63258
FCRL3 Fc receptor-like 3 1.61591
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.53327
MOG myelin oligodendrocyte glycoprotein 1.42236
CEP128 centrosomal protein 128kDa 1.38972
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.35521
TG thyroglobulin 1.25845
FCRL1 Fc receptor-like 1 1.24199
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.16969
TNF tumor necrosis factor 1.16177
FGFR1OP FGFR1 oncogene partner 1.14225
NELFE negative elongation factor complex member E 1.1213
SLA Src-like-adaptor 1.09244
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.04703
RNASET2 ribonuclease T2 1.04239
CD5L CD5 molecule-like 1.01258
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.00059
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.942765
FCRL2 Fc receptor-like 2 0.907652
CFB complement factor B 0.889642
CALD1 caldesmon 1 0.793451
LACTB lactamase, beta 0.734535
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.701779
VAV1 vav 1 guanine nucleotide exchange factor 0.701431
TASP1 taspase, threonine aspartase, 1 0.654063
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.644886
WISP1 WNT1 inducible signaling pathway protein 1 0.629625
STAC SH3 and cysteine rich domain 0.628991
RTKN2 rhotekin 2 0.626907
CSMD3 CUB and Sushi multiple domains 3 0.605341
RIN2 Ras and Rab interactor 2 0.595129
CNTNAP2 contactin associated protein-like 2 0.594038
KALRN kalirin, RhoGEF kinase 0.536325
RNF144A ring finger protein 144A 0.516251
CIPC CLOCK-interacting pacemaker 0.456794
ACSF3 acyl-CoA synthetase family member 3 0.453483
IRF2BPL interferon regulatory factor 2 binding protein-like 0.426021