hymecromone-3383 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the hymecromone-3383 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADRA1B adrenoceptor alpha 1B
AKAP8L A kinase (PRKA) anchor protein 8-like
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALCAM activated leukocyte cell adhesion molecule
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPTL2 angiopoietin-like 2
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ASMT acetylserotonin O-methyltransferase
ATP10A ATPase, class V, type 10A
ATP10B ATPase, class V, type 10B
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
C17ORF53 chromosome 17 open reading frame 53
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD8A CD8a molecule
CDA cytidine deaminase
CDRT1 CMT1A duplicated region transcript 1
CELA3B chymotrypsin-like elastase family, member 3B
CEP295 centrosomal protein 295kDa
CFAP70 cilia and flagella associated protein 70
CLCN1 chloride channel, voltage-sensitive 1
CLDN16 claudin 16
CORT cortistatin
CTGF connective tissue growth factor
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DGCR8 DGCR8 microprocessor complex subunit
EDA ectodysplasin A
FGF16 fibroblast growth factor 16
FRZB frizzled-related protein
FSTL1 follistatin-like 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAS2L1 growth arrest-specific 2 like 1
GK glycerol kinase
GPR37L1 G protein-coupled receptor 37 like 1
GPR39 G protein-coupled receptor 39
GRM1 glutamate receptor, metabotropic 1
GSN gelsolin
GYG2 glycogenin 2
HCG26 HLA complex group 26 (non-protein coding)
HPR haptoglobin-related protein
HSF1 heat shock transcription factor 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1B interleukin 1, beta
IRF4 interferon regulatory factor 4
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLHL25 kelch-like family member 25
KRT16 keratin 16, type I
KRT23 keratin 23, type I
LENEP lens epithelial protein
LIMCH1 LIM and calponin homology domains 1
LTBP2 latent transforming growth factor beta binding protein 2
MAPK14 mitogen-activated protein kinase 14
MCL1 myeloid cell leukemia 1
MMP11 matrix metallopeptidase 11
MRPL41 mitochondrial ribosomal protein L41
MST1 macrophage stimulating 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRL neural retina leucine zipper
NUP188 nucleoporin 188kDa
PARD6B par-6 family cell polarity regulator beta
PCM1 pericentriolar material 1
PDIA2 protein disulfide isomerase family A, member 2
PEX3 peroxisomal biogenesis factor 3
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKP2 plakophilin 2
POU2F2 POU class 2 homeobox 2
PTAFR platelet-activating factor receptor
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RHAG Rh-associated glycoprotein
RPL3L ribosomal protein L3-like
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT4 sirtuin 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLIT1 slit homolog 1 (Drosophila)
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOX10 SRY (sex determining region Y)-box 10
SRSF7 serine/arginine-rich splicing factor 7
TECPR2 tectonin beta-propeller repeat containing 2
TGM2 transglutaminase 2
TPP1 tripeptidyl peptidase I
TRIB2 tribbles pseudokinase 2
TUBB7P tubulin, beta 7, pseudogene
UMOD uromodulin
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZC3H13 zinc finger CCCH-type containing 13
ZER1 zyg-11 related, cell cycle regulator
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
AGO1 argonaute RISC catalytic component 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMCX2 armadillo repeat containing, X-linked 2
ARPIN actin-related protein 2/3 complex inhibitor
ASIC1 acid sensing (proton gated) ion channel 1
ASIC3 acid sensing (proton gated) ion channel 3
ATF7IP2 activating transcription factor 7 interacting protein 2
AUTS2 autism susceptibility candidate 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BHLHE41 basic helix-loop-helix family, member e41
BMP15 bone morphogenetic protein 15
C8ORF60 chromosome 8 open reading frame 60
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMTA2 calmodulin binding transcription activator 2
CDK18 cyclin-dependent kinase 18
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLCN2 chloride channel, voltage-sensitive 2
CLIP4 CAP-GLY domain containing linker protein family, member 4
CPA4 carboxypeptidase A4
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTRL chymotrypsin-like
DDIT3 DNA-damage-inducible transcript 3
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP13 dual specificity phosphatase 13
ETAA1 Ewing tumor-associated antigen 1
FAM184A family with sequence similarity 184, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF23 fibroblast growth factor 23
FLJ11710 uncharacterized protein FLJ11710
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BC histone cluster 1, H2bc
HOXA4 homeobox A4
HOXB2 homeobox B2
IL22 interleukin 22
KCTD17 potassium channel tetramerization domain containing 17
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LINC00597 long intergenic non-protein coding RNA 597
LOC390998 ribosomal protein L10 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYRM9 LYR motif containing 9
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NLRX1 NLR family member X1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCDHA6 protocadherin alpha 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGBD5 piggyBac transposable element derived 5
PHF14 PHD finger protein 14
PLTP phospholipid transfer protein
PLXNB3 plexin B3
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PODXL podocalyxin-like
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRSS53 protease, serine, 53
RAB40AL RAB40A, member RAS oncogene family-like
RNF2 ring finger protein 2
RNF39 ring finger protein 39
RPL23AP32 ribosomal protein L23a pseudogene 32
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERGEF secretion regulating guanine nucleotide exchange factor
SH2B3 SH2B adaptor protein 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D2 TBC1 domain family, member 2
TBKBP1 TBK1 binding protein 1
TCTN1 tectonic family member 1
TEP1 telomerase-associated protein 1
TLN1 talin 1
TMEM242 transmembrane protein 242
TNRC6B trinucleotide repeat containing 6B
USB1 U6 snRNA biogenesis 1
VEGFB vascular endothelial growth factor B
WDR76 WD repeat domain 76
ZNF250 zinc finger protein 250
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF721 zinc finger protein 721