hsa-miR-887 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 887|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 100126347)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-887
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Genes

10 target genes of the hsa-miR-887 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
SHANK3 SH3 and multiple ankyrin repeat domains 3 1.26663
GSK3A glycogen synthase kinase 3 alpha 1.26663
PURB purine-rich element binding protein B 0.997906
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.568687
SPATA2 spermatogenesis associated 2 0.454769
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.159923
PDZRN3 PDZ domain containing ring finger 3 0.115091
IGLON5 IgLON family member 5 0.107229
RBM19 RNA binding motif protein 19 0.09606
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.013856