hsa-miR-874 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 874|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 100126343)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-874
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Genes

265 target genes of the hsa-miR-874 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
PAAF1 proteasomal ATPase-associated factor 1 1.45615
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.45615
USP43 ubiquitin specific peptidase 43 1.45615
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 1.45615
ZDHHC16 zinc finger, DHHC-type containing 16 1.45615
RAB13 RAB13, member RAS oncogene family 1.45615
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.45615
CNTNAP2 contactin associated protein-like 2 1.26663
THAP2 THAP domain containing, apoptosis associated protein 2 1.26663
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.26663
MXI1 MAX interactor 1, dimerization protein 1.26663
PARP14 poly (ADP-ribose) polymerase family, member 14 1.26663
THRA thyroid hormone receptor, alpha 1.26663
TRIM9 tripartite motif containing 9 1.26663
FAM114A1 family with sequence similarity 114, member A1 1.26663
GLDC glycine dehydrogenase (decarboxylating) 1.26663
ADAM19 ADAM metallopeptidase domain 19 1.26663
AQP3 aquaporin 3 (Gill blood group) 1.11641
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 1.11641
FAM63A family with sequence similarity 63, member A 1.11641
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 1.11641
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 1.11641
OSTM1 osteopetrosis associated transmembrane protein 1 1.11641
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 1.11641
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.11641
RGS4 regulator of G-protein signaling 4 0.997906
GRIP1 glutamate receptor interacting protein 1 0.997906
KDM4A lysine (K)-specific demethylase 4A 0.997906
SORT1 sortilin 1 0.997906
TARBP2 TAR (HIV-1) RNA binding protein 2 0.997906
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 0.997906
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like 0.997906
HEG1 heart development protein with EGF-like domains 1 0.997906
LPAR1 lysophosphatidic acid receptor 1 0.997906
VAV3 vav 3 guanine nucleotide exchange factor 0.997906
CUX1 cut-like homeobox 1 0.997906
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.90397
USP8 ubiquitin specific peptidase 8 0.90397
PPP5C protein phosphatase 5, catalytic subunit 0.90397
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 0.90397
NR2C2 nuclear receptor subfamily 2, group C, member 2 0.828473
PCDH11X protocadherin 11 X-linked 0.828473
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.828473
SGSM2 small G protein signaling modulator 2 0.828473
PCDH11Y protocadherin 11 Y-linked 0.828473
OSBPL9 oxysterol binding protein-like 9 0.766596
CXORF23 chromosome X open reading frame 23 0.766596
CHP1 calcineurin-like EF-hand protein 1 0.766596
ESRRA estrogen-related receptor alpha 0.766596
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.766596
FNDC7 fibronectin type III domain containing 7 0.766596
POU3F2 POU class 3 homeobox 2 0.766596
C7ORF43 chromosome 7 open reading frame 43 0.714812
C11ORF45 chromosome 11 open reading frame 45 0.714812
MYO7A myosin VIIA 0.714812
RHOBTB1 Rho-related BTB domain containing 1 0.714812
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.714812
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.714812
RASAL2 RAS protein activator like 2 0.714812
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 0.670641
FAM160B1 family with sequence similarity 160, member B1 0.670641
PRDM1 PR domain containing 1, with ZNF domain 0.670641
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.632343
LPAR5 lysophosphatidic acid receptor 5 0.632343
MBLAC2 metallo-beta-lactamase domain containing 2 0.632343
NRCAM neuronal cell adhesion molecule 0.632343
FMR1 fragile X mental retardation 1 0.632343
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.632343
UNK unkempt family zinc finger 0.632343
SNX24 sorting nexin 24 0.632343
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.598666
AFF3 AF4/FMR2 family, member 3 0.598666
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.598666
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.598666
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.598666
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.568687
EDA2R ectodysplasin A2 receptor 0.568687
SAMD12 sterile alpha motif domain containing 12 0.568687
STRN striatin, calmodulin binding protein 0.568687
TRAF1 TNF receptor-associated factor 1 0.541706
FRMPD4 FERM and PDZ domain containing 4 0.541706
DTNB dystrobrevin, beta 0.541706
NECAB3 N-terminal EF-hand calcium binding protein 3 0.541706
SATB2 SATB homeobox 2 0.517189
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.517189
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.517189
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.49473
CELF4 CUGBP, Elav-like family member 4 0.49473
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.49473
DSCAML1 Down syndrome cell adhesion molecule like 1 0.474009
LSM12 LSM12 homolog (S. cerevisiae) 0.474009
CDK16 cyclin-dependent kinase 16 0.454769
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.454769
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 0.454769
ST5 suppression of tumorigenicity 5 0.454769
RFTN1 raftlin, lipid raft linker 1 0.454769
TENM1 teneurin transmembrane protein 1 0.436802
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.436802
CCDC113 coiled-coil domain containing 113 0.436802
FAM53C family with sequence similarity 53, member C 0.419947
RNFT2 ring finger protein, transmembrane 2 0.419947
RASGEF1A RasGEF domain family, member 1A 0.419947
MEGF11 multiple EGF-like-domains 11 0.419947
NUPL1 nucleoporin like 1 0.419947
EXTL3 exostosin-like glycosyltransferase 3 0.419947
TMEM150A transmembrane protein 150A 0.419947
HOMER2 homer scaffolding protein 2 0.404082
USP34 ubiquitin specific peptidase 34 0.404082
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) 0.389112
LEP leptin 0.389112
RAB11FIP5 RAB11 family interacting protein 5 (class I) 0.389112
GGACT gamma-glutamylamine cyclotransferase 0.389112
HAPLN1 hyaluronan and proteoglycan link protein 1 0.389112
MMP24 matrix metallopeptidase 24 (membrane-inserted) 0.389112
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.389112
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.389112
CRCP CGRP receptor component 0.389112
ZBTB7A zinc finger and BTB domain containing 7A 0.389112
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 0.389112
LRP3 low density lipoprotein receptor-related protein 3 0.389112
RNF121 ring finger protein 121 0.389112
CCDC184 coiled-coil domain containing 184 0.37496
PRR12 proline rich 12 0.37496
GORAB golgin, RAB6-interacting 0.37496
FADS1 fatty acid desaturase 1 0.37496
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.361556
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.361556
MARCH9 membrane-associated ring finger (C3HC4) 9 0.348832
LIN7C lin-7 homolog C (C. elegans) 0.348832
ZNF618 zinc finger protein 618 0.336728
MAP2K4 mitogen-activated protein kinase kinase 4 0.32519
MSRB3 methionine sulfoxide reductase B3 0.32519
ZBTB6 zinc finger and BTB domain containing 6 0.31417
KMT2D lysine (K)-specific methyltransferase 2D 0.31417
FGF1 fibroblast growth factor 1 (acidic) 0.31417
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.303626
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.303626
MOB1B MOB kinase activator 1B 0.303626
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.303626
CHKB choline kinase beta 0.303626
FZD5 frizzled class receptor 5 0.303626
AJAP1 adherens junctions associated protein 1 0.283838
CSMD2 CUB and Sushi multiple domains 2 0.283838
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.274552
LMO4 LIM domain only 4 0.274552
USP31 ubiquitin specific peptidase 31 0.274552
OTUD7B OTU deubiquitinase 7B 0.265648
BEAN1 brain expressed, associated with NEDD4, 1 0.265648
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.257113
MLXIPL MLX interacting protein-like 0.257113
GDF11 growth differentiation factor 11 0.257113
KALRN kalirin, RhoGEF kinase 0.248923
BEND4 BEN domain containing 4 0.241055
ZCCHC14 zinc finger, CCHC domain containing 14 0.241055
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.241055
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.241055
PTCHD1 patched domain containing 1 0.23348
FBXO33 F-box protein 33 0.23348
DCAF10 DDB1 and CUL4 associated factor 10 0.23348
TMF1 TATA element modulatory factor 1 0.226173
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 0.226173
SPTB spectrin, beta, erythrocytic 0.226173
ARL4C ADP-ribosylation factor-like 4C 0.226173
HEPN1 hepatocellular carcinoma, down-regulated 1 0.226173
GID4 GID complex subunit 4 0.226173
RNF4 ring finger protein 4 0.226173
KIF17 kinesin family member 17 0.219115
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.219115
TMEM55B transmembrane protein 55B 0.212286
LIPH lipase, member H 0.212286
LDB1 LIM domain binding 1 0.199275
IST1 increased sodium tolerance 1 homolog (yeast) 0.199275
PTGFRN prostaglandin F2 receptor inhibitor 0.199275
IL2RB interleukin 2 receptor, beta 0.199275
ZFYVE1 zinc finger, FYVE domain containing 1 0.193083
USP46 ubiquitin specific peptidase 46 0.193083
GGCX gamma-glutamyl carboxylase 0.187098
VGLL4 vestigial-like family member 4 0.187098
ARRB1 arrestin, beta 1 0.187098
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 0.181316
LUZP1 leucine zipper protein 1 0.175726
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.17031
ATF7 activating transcription factor 7 0.17031
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.165047
PANK1 pantothenate kinase 1 0.159923
LMTK2 lemur tyrosine kinase 2 0.159923
MED12L mediator complex subunit 12-like 0.15008
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 0.145356
CFL1 cofilin 1 (non-muscle) 0.145356
NRXN2 neurexin 2 0.145356
AQP2 aquaporin 2 (collecting duct) 0.140752
FSTL4 follistatin-like 4 0.140752
DHDDS dehydrodolichyl diphosphate synthase 0.136254
SEPT3 septin 3 0.136254
STOML1 stomatin (EPB72)-like 1 0.131849
PSD3 pleckstrin and Sec7 domain containing 3 0.131849
LMX1A LIM homeobox transcription factor 1, alpha 0.127531
FOSL2 FOS-like antigen 2 0.127531
E2F3 E2F transcription factor 3 0.123298
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.119151
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.119151
RNF43 ring finger protein 43 0.119151
FAXC failed axon connections homolog (Drosophila) 0.119151
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.115091
RASL10B RAS-like, family 10, member B 0.115091
ATXN7L3 ataxin 7-like 3 0.111118
CPLX2 complexin 2 0.107229
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.103424
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.099701
GSK3B glycogen synthase kinase 3 beta 0.099701
ADCY6 adenylate cyclase 6 0.099701
ESR1 estrogen receptor 1 0.09606
C11ORF87 chromosome 11 open reading frame 87 0.09606
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 0.09606
KIAA1324 KIAA1324 0.088999
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.085563
TTBK1 tau tubulin kinase 1 0.082179
TET2 tet methylcytosine dioxygenase 2 0.078844
THRB thyroid hormone receptor, beta 0.078844
ZNF282 zinc finger protein 282 0.078844
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.072324
SMC1A structural maintenance of chromosomes 1A 0.069137
ATXN1 ataxin 1 0.069137
BACE1 beta-site APP-cleaving enzyme 1 0.062888
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.059817
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.056784
IKZF4 IKAROS family zinc finger 4 (Eos) 0.056784
RLIM ring finger protein, LIM domain interacting 0.056784
ICA1L islet cell autoantigen 1,69kDa-like 0.056784
PHF21A PHD finger protein 21A 0.056784
TMEM127 transmembrane protein 127 0.053794
SETD7 SET domain containing (lysine methyltransferase) 7 0.050854
PSD pleckstrin and Sec7 domain containing 0.050854
BMF Bcl2 modifying factor 0.045136
PODNL1 podocan-like 1 0.045136
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.045136
FOXN3 forkhead box N3 0.042355
SLC46A1 solute carrier family 46 (folate transporter), member 1 0.039622
SNX27 sorting nexin family member 27 0.039622
RBM8A RNA binding motif protein 8A 0.03694
POU2F1 POU class 2 homeobox 1 0.03694
EEF2K eukaryotic elongation factor 2 kinase 0.034317
MTMR3 myotubularin related protein 3 0.034317
CBX7 chromobox homolog 7 0.031759
DCX doublecortin 0.031759
DGKG diacylglycerol kinase, gamma 90kDa 0.029271
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.026857
CDC14B cell division cycle 14B 0.026857
KIF3B kinesin family member 3B 0.026857
GNG2 guanine nucleotide binding protein (G protein), gamma 2 0.026857
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.026857
RGS6 regulator of G-protein signaling 6 0.02452
TUB tubby bipartite transcription factor 0.02226
HIPK2 homeodomain interacting protein kinase 2 0.02226
ETV5 ets variant 5 0.017945
GPC6 glypican 6 0.017945
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.015875
TLCD2 TLC domain containing 2 0.015875
ABHD2 abhydrolase domain containing 2 0.015875
PCYT1B phosphate cytidylyltransferase 1, choline, beta 0.009975
ZDHHC3 zinc finger, DHHC-type containing 3 0.008128
FMNL3 formin-like 3 0.008128
C1ORF95 chromosome 1 open reading frame 95 0.004732
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.003282
SRRM4 serine/arginine repetitive matrix 4 0.002088