hsa-miR-500a Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 500a|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 574502)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-500a
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Genes

311 target genes of the hsa-miR-500a microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
MICU3 mitochondrial calcium uptake family, member 3 1.45615
PEX2 peroxisomal biogenesis factor 2 1.45615
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 1.45615
LRP1B low density lipoprotein receptor-related protein 1B 1.45615
GATAD2B GATA zinc finger domain containing 2B 1.45615
PRDM4 PR domain containing 4 1.26663
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.26663
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 1.26663
PLA2G12A phospholipase A2, group XIIA 1.26663
SATB2 SATB homeobox 2 1.26663
CHD1 chromodomain helicase DNA binding protein 1 1.26663
EIF3A eukaryotic translation initiation factor 3, subunit A 1.26663
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.26663
TMEM47 transmembrane protein 47 1.26663
ZBTB34 zinc finger and BTB domain containing 34 1.26663
IKZF2 IKAROS family zinc finger 2 (Helios) 1.26663
PNN pinin, desmosome associated protein 1.26663
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.26663
ZBTB20 zinc finger and BTB domain containing 20 1.26663
SCP2 sterol carrier protein 2 1.11641
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 1.11641
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 1.11641
RFESD Rieske (Fe-S) domain containing 1.11641
CLMN calmin (calponin-like, transmembrane) 0.997906
HOXD3 homeobox D3 0.997906
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.997906
AKIRIN2 akirin 2 0.997906
ZNF175 zinc finger protein 175 0.997906
CACHD1 cache domain containing 1 0.90397
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.90397
U2SURP U2 snRNP-associated SURP domain containing 0.90397
ARHGAP23 Rho GTPase activating protein 23 0.90397
MMP8 matrix metallopeptidase 8 0.90397
NOX1 NADPH oxidase 1 0.90397
EPHA5 EPH receptor A5 0.90397
LEPROTL1 leptin receptor overlapping transcript-like 1 0.828473
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.828473
PKNOX1 PBX/knotted 1 homeobox 1 0.828473
ADRB1 adrenoceptor beta 1 0.828473
UBE2B ubiquitin-conjugating enzyme E2B 0.828473
RCOR3 REST corepressor 3 0.828473
PRPF38A pre-mRNA processing factor 38A 0.766596
ELAVL4 ELAV like neuron-specific RNA binding protein 4 0.766596
SHISA6 shisa family member 6 0.766596
BAMBI BMP and activin membrane-bound inhibitor 0.766596
CHD5 chromodomain helicase DNA binding protein 5 0.714812
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.714812
ERRFI1 ERBB receptor feedback inhibitor 1 0.714812
WDR59 WD repeat domain 59 0.714812
HPSE heparanase 0.714812
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 0.714812
HIATL1 hippocampus abundant transcript-like 1 0.670641
TMEM170B transmembrane protein 170B 0.670641
ZC3H7A zinc finger CCCH-type containing 7A 0.670641
SYNC syncoilin, intermediate filament protein 0.670641
OCLN occludin 0.670641
PSD3 pleckstrin and Sec7 domain containing 3 0.670641
MIA3 melanoma inhibitory activity family, member 3 0.670641
SULF1 sulfatase 1 0.670641
CNOT1 CCR4-NOT transcription complex, subunit 1 0.670641
CELF2 CUGBP, Elav-like family member 2 0.632343
QSOX2 quiescin Q6 sulfhydryl oxidase 2 0.632343
GADD45A growth arrest and DNA-damage-inducible, alpha 0.632343
NEGR1 neuronal growth regulator 1 0.632343
SERTAD2 SERTA domain containing 2 0.632343
RBPMS2 RNA binding protein with multiple splicing 2 0.598666
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.598666
ZFYVE28 zinc finger, FYVE domain containing 28 0.598666
ANKRD40 ankyrin repeat domain 40 0.598666
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.598666
IPO9 importin 9 0.568687
PARP1 poly (ADP-ribose) polymerase 1 0.568687
WAS Wiskott-Aldrich syndrome 0.568687
UBE4B ubiquitination factor E4B 0.568687
GRPEL2 GrpE-like 2, mitochondrial (E. coli) 0.568687
STXBP5L syntaxin binding protein 5-like 0.568687
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.541706
TMEM106B transmembrane protein 106B 0.541706
PAQR8 progestin and adipoQ receptor family member VIII 0.541706
GPR85 G protein-coupled receptor 85 0.541706
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.517189
GRAMD1C GRAM domain containing 1C 0.517189
TMEM220 transmembrane protein 220 0.517189
SREK1IP1 SREK1-interacting protein 1 0.517189
RBM17 RNA binding motif protein 17 0.517189
MMS22L MMS22-like, DNA repair protein 0.517189
TRERF1 transcriptional regulating factor 1 0.517189
GLI3 GLI family zinc finger 3 0.517189
TRAPPC6B trafficking protein particle complex 6B 0.517189
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.517189
STK16 serine/threonine kinase 16 0.517189
SERBP1 SERPINE1 mRNA binding protein 1 0.517189
ERBB3 erb-b2 receptor tyrosine kinase 3 0.49473
TNNI2 troponin I type 2 (skeletal, fast) 0.49473
RDX radixin 0.49473
ZNF233 zinc finger protein 233 0.49473
C10ORF131 chromosome 10 open reading frame 131 0.474009
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.474009
NXPH1 neurexophilin 1 0.474009
SKP1 S-phase kinase-associated protein 1 0.474009
YTHDC1 YTH domain containing 1 0.474009
RBM19 RNA binding motif protein 19 0.454769
CEP70 centrosomal protein 70kDa 0.454769
AZIN1 antizyme inhibitor 1 0.454769
LURAP1 leucine rich adaptor protein 1 0.454769
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 0.436802
HHLA2 HERV-H LTR-associating 2 0.436802
ICA1L islet cell autoantigen 1,69kDa-like 0.436802
DCLK1 doublecortin-like kinase 1 0.436802
INSR insulin receptor 0.419947
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.419947
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.404082
DCK deoxycytidine kinase 0.404082
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.404082
MTDH metadherin 0.404082
FAM3C family with sequence similarity 3, member C 0.404082
CSRNP2 cysteine-serine-rich nuclear protein 2 0.404082
RBM12 RNA binding motif protein 12 0.404082
COIL coilin 0.37496
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.37496
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.37496
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.37496
MACROD2 MACRO domain containing 2 0.361556
POU3F1 POU class 3 homeobox 1 0.361556
MPHOSPH8 M-phase phosphoprotein 8 0.361556
DENND4B DENN/MADD domain containing 4B 0.348832
SOX14 SRY (sex determining region Y)-box 14 0.336728
PTPRD protein tyrosine phosphatase, receptor type, D 0.336728
AQP4 aquaporin 4 0.336728
TP53BP2 tumor protein p53 binding protein 2 0.336728
DESI2 desumoylating isopeptidase 2 0.336728
DMD dystrophin 0.336728
HYDIN HYDIN, axonemal central pair apparatus protein 0.32519
MED8 mediator complex subunit 8 0.32519
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.32519
SOX11 SRY (sex determining region Y)-box 11 0.31417
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.31417
STRN3 striatin, calmodulin binding protein 3 0.31417
DAZ4 deleted in azoospermia 4 0.31417
ERO1L ERO1-like (S. cerevisiae) 0.31417
DAZ2 deleted in azoospermia 2 0.31417
DAZ3 deleted in azoospermia 3 0.31417
DAZ1 deleted in azoospermia 1 0.31417
CAND1 cullin-associated and neddylation-dissociated 1 0.303626
SRSF1 serine/arginine-rich splicing factor 1 0.303626
HOXB8 homeobox B8 0.303626
PTCH1 patched 1 0.303626
NEK7 NIMA-related kinase 7 0.293524
CCNF cyclin F 0.293524
IL6R interleukin 6 receptor 0.283838
OLIG3 oligodendrocyte transcription factor 3 0.274552
ACO2 aconitase 2, mitochondrial 0.274552
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 0.274552
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.265648
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.265648
CYTH3 cytohesin 3 0.265648
ZCCHC14 zinc finger, CCHC domain containing 14 0.265648
TCEA1 transcription elongation factor A (SII), 1 0.257113
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.257113
FNDC5 fibronectin type III domain containing 5 0.257113
ACSL3 acyl-CoA synthetase long-chain family member 3 0.257113
PTPRJ protein tyrosine phosphatase, receptor type, J 0.248923
DENR density-regulated protein 0.248923
CDK14 cyclin-dependent kinase 14 0.248923
SH2B3 SH2B adaptor protein 3 0.241055
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.23348
GSE1 Gse1 coiled-coil protein 0.23348
COMMD10 COMM domain containing 10 0.226173
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.226173
TLE4 transducin-like enhancer of split 4 0.226173
HES5 hes family bHLH transcription factor 5 0.219115
MFSD4 major facilitator superfamily domain containing 4 0.219115
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.219115
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.219115
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.212286
RAB11FIP4 RAB11 family interacting protein 4 (class II) 0.212286
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 0.205675
NEK6 NIMA-related kinase 6 0.205675
TXNRD1 thioredoxin reductase 1 0.199275
IL15RA interleukin 15 receptor, alpha 0.193083
TBC1D20 TBC1 domain family, member 20 0.193083
CLDN12 claudin 12 0.193083
PAPD5 PAP associated domain containing 5 0.187098
KMT2A lysine (K)-specific methyltransferase 2A 0.187098
MAP4 microtubule-associated protein 4 0.187098
GSPT1 G1 to S phase transition 1 0.181316
AJUBA ajuba LIM protein 0.181316
CCSER2 coiled-coil serine-rich protein 2 0.175726
ZNF281 zinc finger protein 281 0.175726
CDK19 cyclin-dependent kinase 19 0.175726
ZDHHC20 zinc finger, DHHC-type containing 20 0.175726
FAM126B family with sequence similarity 126, member B 0.175726
VIMP VCP-interacting membrane selenoprotein 0.17031
PHIP pleckstrin homology domain interacting protein 0.17031
RBM27 RNA binding motif protein 27 0.165047
ACADSB acyl-CoA dehydrogenase, short/branched chain 0.165047
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.165047
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta 0.165047
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.159923
PHB prohibitin 0.159923
DCAF12 DDB1 and CUL4 associated factor 12 0.154935
DCC DCC netrin 1 receptor 0.154935
CALCRL calcitonin receptor-like 0.15008
DLC1 DLC1 Rho GTPase activating protein 0.15008
RPGRIP1L RPGRIP1-like 0.145356
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.145356
SLC39A9 solute carrier family 39, member 9 0.145356
KY kyphoscoliosis peptidase 0.140752
AGO1 argonaute RISC catalytic component 1 0.140752
C2ORF88 chromosome 2 open reading frame 88 0.136254
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.136254
LCORL ligand dependent nuclear receptor corepressor-like 0.136254
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.131849
MBD6 methyl-CpG binding domain protein 6 0.131849
TLX2 T-cell leukemia homeobox 2 0.131849
GPR180 G protein-coupled receptor 180 0.131849
RNF165 ring finger protein 165 0.131849
KLF3 Kruppel-like factor 3 (basic) 0.131849
ZFAND5 zinc finger, AN1-type domain 5 0.123298
AMOT angiomotin 0.119151
FOXO4 forkhead box O4 0.119151
SAE1 SUMO1 activating enzyme subunit 1 0.115091
ARF6 ADP-ribosylation factor 6 0.115091
KIAA1324L KIAA1324-like 0.115091
CAPRIN1 cell cycle associated protein 1 0.111118
RCVRN recoverin 0.111118
FAM20B family with sequence similarity 20, member B 0.111118
ATG12 autophagy related 12 0.107229
RSU1 Ras suppressor protein 1 0.103424
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.103424
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.103424
GREM2 gremlin 2, DAN family BMP antagonist 0.099701
CCDC71L coiled-coil domain containing 71-like 0.099701
ZNF527 zinc finger protein 527 0.099701
LTN1 listerin E3 ubiquitin protein ligase 1 0.099701
SCRN1 secernin 1 0.09606
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.09606
REPS2 RALBP1 associated Eps domain containing 2 0.09606
ZMYM2 zinc finger, MYM-type 2 0.092495
ARFGEF3 ARFGEF family member 3 0.092495
RTN4RL1 reticulon 4 receptor-like 1 0.092495
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.088999
PRKCA protein kinase C, alpha 0.088999
C2ORF91 chromosome 2 open reading frame 91 0.088999
FGF9 fibroblast growth factor 9 0.085563
C11ORF87 chromosome 11 open reading frame 87 0.085563
CSMD2 CUB and Sushi multiple domains 2 0.082179
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.082179
FZD3 frizzled class receptor 3 0.082179
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.082179
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.075559
RC3H1 ring finger and CCCH-type domains 1 0.075559
RMDN1 regulator of microtubule dynamics 1 0.075559
SOX4 SRY (sex determining region Y)-box 4 0.075559
DCX doublecortin 0.075559
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.072324
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.072324
STX16 syntaxin 16 0.072324
PARVA parvin, alpha 0.069137
NCMAP noncompact myelin associated protein 0.065994
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 0.062888
AAK1 AP2 associated kinase 1 0.062888
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.056784
CLYBL citrate lyase beta like 0.056784
ANKRD12 ankyrin repeat domain 12 0.056784
AFF2 AF4/FMR2 family, member 2 0.053794
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.050854
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.045136
FAM126A family with sequence similarity 126, member A 0.042355
SLAIN2 SLAIN motif family, member 2 0.042355
RAB14 RAB14, member RAS oncogene family 0.042355
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.042355
DCP1A decapping mRNA 1A 0.039622
LARP4 La ribonucleoprotein domain family, member 4 0.039622
RBM33 RNA binding motif protein 33 0.039622
BTG1 B-cell translocation gene 1, anti-proliferative 0.039622
THRB thyroid hormone receptor, beta 0.03694
EIF4E3 eukaryotic translation initiation factor 4E family member 3 0.03694
PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.034317
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.034317
SMC1A structural maintenance of chromosomes 1A 0.034317
KIAA0232 KIAA0232 0.031759
DHDDS dehydrodolichyl diphosphate synthase 0.031759
FAM134A family with sequence similarity 134, member A 0.031759
PHACTR2 phosphatase and actin regulator 2 0.031759
MCTS1 malignant T cell amplified sequence 1 0.029271
SPRY3 sprouty homolog 3 (Drosophila) 0.029271
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.026857
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.026857
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 0.02452
FAXC failed axon connections homolog (Drosophila) 0.02452
BCLAF1 BCL2-associated transcription factor 1 0.02226
ZNF652 zinc finger protein 652 0.02226
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 0.020071
WSCD2 WSC domain containing 2 0.020071
CIT citron rho-interacting serine/threonine kinase 0.020071
MACC1 metastasis associated in colon cancer 1 0.017945
INO80D INO80 complex subunit D 0.017945
COX18 COX18 cytochrome c oxidase assembly factor 0.015875
PCGF3 polycomb group ring finger 3 0.013856
SAP30L SAP30-like 0.011888
ZNF24 zinc finger protein 24 0.011888
ZNF618 zinc finger protein 618 0.011888
EPM2AIP1 EPM2A (laforin) interacting protein 1 0.011888
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 0.008128
TNPO1 transportin 1 0.008128
ZNF148 zinc finger protein 148 0.006367
WASF2 WAS protein family, member 2 0.006367
CUL3 cullin 3 0.004732
CTSV cathepsin V 0.004732
TNRC6B trinucleotide repeat containing 6B 0.002088