hsa-miR-451a Gene Set

Dataset MiRTarBase microRNA Targets
Category physical interactions
Type microRNA
Description microRNA 451a|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 574411)
External Link http://mirtarbase.mbc.nctu.edu.tw/php/detail.php?mirtid=MIRT000046
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Genes

12 target genes of the hsa-miR-451a microRNA in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BCL2 B-cell CLL/lymphoma 2
CAB39 calcium binding protein 39
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MYC v-myc avian myelocytomatosis viral oncogene homolog
RAB14 RAB14, member RAS oncogene family
TMED7 transmembrane emp24 protein transport domain containing 7
UBE2H ubiquitin-conjugating enzyme E2H