hsa-miR-451 Gene Set

Dataset TargetScan Predicted Nonconserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 451a|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 574411)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-451
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Genes

57 target genes of the hsa-miR-451 microRNA predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.

Symbol Name Standardized Value
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 1.99187
MYLK3 myosin light chain kinase 3 1.7397
CAV1 caveolin 1, caveolae protein, 22kDa 1.7397
CUX2 cut-like homeobox 2 1.7397
CXCL16 chemokine (C-X-C motif) ligand 16 1.7397
CXORF21 chromosome X open reading frame 21 1.7397
SEC23IP SEC23 interacting protein 1.55165
MEGF6 multiple EGF-like-domains 6 1.55165
MBP myelin basic protein 1.40969
DCAF5 DDB1 and CUL4 associated factor 5 1.40969
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 1.40969
MR1 major histocompatibility complex, class I-related 1.2992
KIF24 kinesin family member 24 1.2992
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.2992
C16ORF72 chromosome 16 open reading frame 72 1.2992
SPC25 SPC25, NDC80 kinetochore complex component 1.20993
NHSL1 NHS-like 1 1.20993
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 1.20993
UBR5 ubiquitin protein ligase E3 component n-recognin 5 1.20993
BATF basic leucine zipper transcription factor, ATF-like 1.20993
ADARB1 adenosine deaminase, RNA-specific, B1 1.13535
EVL Enah/Vasp-like 1.13535
CBLN4 cerebellin 4 precursor 1.13535
ZMAT3 zinc finger, matrin-type 3 1.07142
ADAM10 ADAM metallopeptidase domain 10 1.07142
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 1.07142
CSPP1 centrosome and spindle pole associated protein 1 1.0155
PTTG1IP pituitary tumor-transforming 1 interacting protein 1.0155
FBLN5 fibulin 5 1.0155
MAU2 MAU2 sister chromatid cohesion factor 1.0155
DBX2 developing brain homeobox 2 1.0155
WDFY2 WD repeat and FYVE domain containing 2 1.0155
GDI1 GDP dissociation inhibitor 1 0.965816
ACADSB acyl-CoA dehydrogenase, short/branched chain 0.965816
GRSF1 G-rich RNA sequence binding factor 1 0.965816
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.965816
NAMPT nicotinamide phosphoribosyltransferase 0.921135
POU3F2 POU class 3 homeobox 2 0.921135
PPIE peptidylprolyl isomerase E (cyclophilin E) 0.921135
EREG epiregulin 0.921135
C21ORF91 chromosome 21 open reading frame 91 0.921135
ATF2 activating transcription factor 2 0.921135
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.880544
FNTA farnesyltransferase, CAAX box, alpha 0.880544
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.880544
TARP TCR gamma alternate reading frame protein 0.880544
ZDHHC23 zinc finger, DHHC-type containing 23 0.880544
CPNE3 copine III 0.880544
RPL13 ribosomal protein L13 0.843347
ZIC3 Zic family member 3 0.843347
GADL1 glutamate decarboxylase-like 1 0.843347
FAM159B family with sequence similarity 159, member B 0.843347
CRIP2 cysteine-rich protein 2 0.809003
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.809003
KLF11 Kruppel-like factor 11 0.809003
RAB14 RAB14, member RAS oncogene family 0.809003
SMLR1 small leucine-rich protein 1 0.809003