hsa-miR-451 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 451a|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 574411)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-451
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Genes

20 target genes of the hsa-miR-451 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.45615
OSR1 odd-skipped related transciption factor 1 1.45615
TTN titin 1.11641
C11ORF30 chromosome 11 open reading frame 30 0.766596
AEBP2 AE binding protein 2 0.766596
S1PR2 sphingosine-1-phosphate receptor 2 0.714812
MEX3C mex-3 RNA binding family member C 0.670641
CAB39 calcium binding protein 39 0.49473
SAMD4B sterile alpha motif domain containing 4B 0.389112
TSC1 tuberous sclerosis 1 0.31417
TBX1 T-box 1 0.31417
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.283838
PRR12 proline rich 12 0.274552
MEF2D myocyte enhancer factor 2D 0.274552
FBXO33 F-box protein 33 0.248923
PMM2 phosphomannomutase 2 0.212286
TRIM66 tripartite motif containing 66 0.175726
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.17031
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.15008
GATAD2B GATA zinc finger domain containing 2B 0.107229