hsa-miR-18b Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 18b|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 574033)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-18b
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Genes

275 target genes of the hsa-miR-18b microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
EPB41L1 erythrocyte membrane protein band 4.1-like 1 1.45615
FAM3C family with sequence similarity 3, member C 1.45615
FGF1 fibroblast growth factor 1 (acidic) 1.45615
DICER1 dicer 1, ribonuclease type III 1.45615
HSF5 heat shock transcription factor family member 5 1.45615
ERI1 exoribonuclease 1 1.45615
FBXL3 F-box and leucine-rich repeat protein 3 1.45615
ZNF367 zinc finger protein 367 1.45615
PHC3 polyhomeotic homolog 3 (Drosophila) 1.45615
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.45615
HEATR5A HEAT repeat containing 5A 1.45615
ATM ATM serine/threonine kinase 1.45615
PHF20L1 PHD finger protein 20-like 1 1.45615
TRAPPC8 trafficking protein particle complex 8 1.26663
HLF hepatic leukemia factor 1.26663
MAP7D1 MAP7 domain containing 1 1.26663
CREBL2 cAMP responsive element binding protein-like 2 1.26663
GIGYF1 GRB10 interacting GYF protein 1 1.26663
THBD thrombomodulin 1.26663
ATXN1 ataxin 1 1.26663
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 1.26663
PARD6B par-6 family cell polarity regulator beta 1.26663
HMBOX1 homeobox containing 1 1.26663
SH3BP4 SH3-domain binding protein 4 1.26663
INADL InaD-like (Drosophila) 1.26663
TMEM170B transmembrane protein 170B 1.26663
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.11641
PTP4A3 protein tyrosine phosphatase type IVA, member 3 1.11641
MYLK myosin light chain kinase 1.11641
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.11641
XYLT2 xylosyltransferase II 1.11641
FAM136A family with sequence similarity 136, member A 1.11641
BRWD1 bromodomain and WD repeat domain containing 1 1.11641
MAPK4 mitogen-activated protein kinase 4 1.11641
ZCCHC3 zinc finger, CCHC domain containing 3 1.11641
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.11641
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) 1.11641
RAB11FIP2 RAB11 family interacting protein 2 (class I) 1.11641
NCOA1 nuclear receptor coactivator 1 1.11641
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.997906
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.997906
GCLC glutamate-cysteine ligase, catalytic subunit 0.997906
DAAM2 dishevelled associated activator of morphogenesis 2 0.997906
INPPL1 inositol polyphosphate phosphatase-like 1 0.997906
SMAP2 small ArfGAP2 0.997906
BEND3 BEN domain containing 3 0.997906
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.90397
SOX6 SRY (sex determining region Y)-box 6 0.90397
ZFP62 ZFP62 zinc finger protein 0.90397
PDE4D phosphodiesterase 4D, cAMP-specific 0.90397
ETV6 ets variant 6 0.90397
IRF2 interferon regulatory factor 2 0.90397
ELOVL1 ELOVL fatty acid elongase 1 0.90397
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.90397
KLHL20 kelch-like family member 20 0.828473
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.828473
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.828473
CNTNAP1 contactin associated protein 1 0.828473
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.828473
TLL2 tolloid-like 2 0.828473
C22ORF31 chromosome 22 open reading frame 31 0.828473
ADD3 adducin 3 (gamma) 0.828473
FAM166B family with sequence similarity 166, member B 0.766596
CTGF connective tissue growth factor 0.766596
TBPL1 TBP-like 1 0.766596
PTGFRN prostaglandin F2 receptor inhibitor 0.766596
ORAI3 ORAI calcium release-activated calcium modulator 3 0.766596
DIRAS2 DIRAS family, GTP-binding RAS-like 2 0.766596
TTPAL tocopherol (alpha) transfer protein-like 0.766596
ANKRD13C ankyrin repeat domain 13C 0.714812
HSF2 heat shock transcription factor 2 0.714812
XYLT1 xylosyltransferase I 0.714812
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.714812
FRYL FRY-like 0.714812
NEO1 neogenin 1 0.714812
RUNX1 runt-related transcription factor 1 0.714812
RNF4 ring finger protein 4 0.714812
PDZD2 PDZ domain containing 2 0.714812
KIAA0513 KIAA0513 0.714812
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.670641
RABGAP1 RAB GTPase activating protein 1 0.670641
FNBP1 formin binding protein 1 0.670641
UBTD2 ubiquitin domain containing 2 0.670641
SORBS2 sorbin and SH3 domain containing 2 0.670641
SMAD2 SMAD family member 2 0.632343
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.632343
BTG3 BTG family, member 3 0.632343
RORA RAR-related orphan receptor A 0.632343
FRS2 fibroblast growth factor receptor substrate 2 0.632343
PSD3 pleckstrin and Sec7 domain containing 3 0.632343
FNDC3B fibronectin type III domain containing 3B 0.598666
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.598666
HCFC2 host cell factor C2 0.568687
OLFML2B olfactomedin-like 2B 0.568687
NOTCH2 notch 2 0.568687
CLCC1 chloride channel CLIC-like 1 0.568687
C5ORF30 chromosome 5 open reading frame 30 0.568687
PHF19 PHD finger protein 19 0.568687
UHMK1 U2AF homology motif (UHM) kinase 1 0.568687
CDK19 cyclin-dependent kinase 19 0.568687
ATXN1L ataxin 1-like 0.568687
TMEM2 transmembrane protein 2 0.568687
NXT2 nuclear transport factor 2-like export factor 2 0.541706
THBS1 thrombospondin 1 0.541706
BRWD3 bromodomain and WD repeat domain containing 3 0.541706
OSBP2 oxysterol binding protein 2 0.541706
ASXL2 additional sex combs like transcriptional regulator 2 0.541706
KDM5B lysine (K)-specific demethylase 5B 0.541706
GNPDA2 glucosamine-6-phosphate deaminase 2 0.541706
PKNOX1 PBX/knotted 1 homeobox 1 0.541706
ENDOD1 endonuclease domain containing 1 0.541706
EXPH5 exophilin 5 0.541706
F3 coagulation factor III (thromboplastin, tissue factor) 0.517189
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 0.517189
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.517189
LMO4 LIM domain only 4 0.517189
HEG1 heart development protein with EGF-like domains 1 0.49473
USP24 ubiquitin specific peptidase 24 0.49473
IGF1 insulin-like growth factor 1 (somatomedin C) 0.49473
RAB5C RAB5C, member RAS oncogene family 0.49473
TWF1 twinfilin actin binding protein 1 0.49473
AEBP2 AE binding protein 2 0.474009
MBNL1 muscleblind-like splicing regulator 1 0.474009
FCHSD2 FCH and double SH3 domains 2 0.454769
FOXH1 forkhead box H1 0.454769
TRIOBP TRIO and F-actin binding protein 0.454769
PHF2 PHD finger protein 2 0.454769
ZCCHC4 zinc finger, CCHC domain containing 4 0.436802
SIX3 SIX homeobox 3 0.436802
ATP13A1 ATPase type 13A1 0.436802
CEP85L centrosomal protein 85kDa-like 0.436802
KCMF1 potassium channel modulatory factor 1 0.436802
SUCO SUN domain containing ossification factor 0.436802
FAM229B family with sequence similarity 229, member B 0.419947
STK4 serine/threonine kinase 4 0.419947
NRG1 neuregulin 1 0.419947
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.419947
FBXO28 F-box protein 28 0.419947
FAM192A family with sequence similarity 192, member A 0.419947
TMEM248 transmembrane protein 248 0.419947
TENM3 teneurin transmembrane protein 3 0.404082
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.404082
TEX2 testis expressed 2 0.404082
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.404082
RAB22A RAB22A, member RAS oncogene family 0.404082
CCND2 cyclin D2 0.404082
OTX1 orthodenticle homeobox 1 0.404082
BHLHE22 basic helix-loop-helix family, member e22 0.389112
CDK2 cyclin-dependent kinase 2 0.389112
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 0.37496
SIM2 single-minded family bHLH transcription factor 2 0.37496
ZCCHC24 zinc finger, CCHC domain containing 24 0.37496
TPM3 tropomyosin 3 0.37496
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 0.37496
CLIP3 CAP-GLY domain containing linker protein 3 0.361556
RGS4 regulator of G-protein signaling 4 0.361556
SAR1A secretion associated, Ras related GTPase 1A 0.361556
MARCH5 membrane-associated ring finger (C3HC4) 5 0.361556
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.348832
ATXN7L1 ataxin 7-like 1 0.348832
SIK3 SIK family kinase 3 0.348832
MEF2D myocyte enhancer factor 2D 0.336728
TENM4 teneurin transmembrane protein 4 0.32519
UNG uracil-DNA glycosylase 0.31417
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.31417
CLCN4 chloride channel, voltage-sensitive 4 0.31417
CCDC88A coiled-coil domain containing 88A 0.303626
NDFIP1 Nedd4 family interacting protein 1 0.303626
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.293524
SNRK SNF related kinase 0.293524
ZBTB4 zinc finger and BTB domain containing 4 0.293524
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.293524
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.293524
FOSL2 FOS-like antigen 2 0.283838
ESR1 estrogen receptor 1 0.283838
DOCK4 dedicator of cytokinesis 4 0.283838
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 0.274552
TRIB2 tribbles pseudokinase 2 0.274552
PIAS3 protein inhibitor of activated STAT, 3 0.274552
KLHL3 kelch-like family member 3 0.274552
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.274552
YBX3 Y box binding protein 3 0.274552
AKR1D1 aldo-keto reductase family 1, member D1 0.274552
NOS1 nitric oxide synthase 1 (neuronal) 0.274552
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.265648
ALCAM activated leukocyte cell adhesion molecule 0.265648
ZSCAN30 zinc finger and SCAN domain containing 30 0.257113
SLC35E1 solute carrier family 35, member E1 0.257113
KCTD16 potassium channel tetramerization domain containing 16 0.257113
LAT linker for activation of T cells 0.257113
ZNF280C zinc finger protein 280C 0.257113
C1ORF21 chromosome 1 open reading frame 21 0.241055
SEC14L3 SEC14-like 3 (S. cerevisiae) 0.23348
ZBTB47 zinc finger and BTB domain containing 47 0.23348
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.23348
UBE2Z ubiquitin-conjugating enzyme E2Z 0.23348
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.23348
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.219115
CSRNP3 cysteine-serine-rich nuclear protein 3 0.219115
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.219115
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.219115
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.219115
SH3KBP1 SH3-domain kinase binding protein 1 0.212286
RIMKLA ribosomal modification protein rimK-like family member A 0.212286
TRIM2 tripartite motif containing 2 0.205675
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.199275
HMG20B high mobility group 20B 0.193083
SATB1 SATB homeobox 1 0.193083
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.187098
INO80D INO80 complex subunit D 0.187098
KDM2A lysine (K)-specific demethylase 2A 0.181316
NIPAL3 NIPA-like domain containing 3 0.181316
FGFR3 fibroblast growth factor receptor 3 0.175726
OCRL oculocerebrorenal syndrome of Lowe 0.175726
TAOK1 TAO kinase 1 0.175726
LIF leukemia inhibitory factor 0.175726
MYO1C myosin IC 0.17031
NREP neuronal regeneration related protein 0.165047
CORO2A coronin, actin binding protein, 2A 0.165047
KIAA0907 KIAA0907 0.159923
NCOA2 nuclear receptor coactivator 2 0.159923
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.159923
BBX bobby sox homolog (Drosophila) 0.15008
CADM2 cell adhesion molecule 2 0.15008
LIN28A lin-28 homolog A (C. elegans) 0.15008
TNRC6B trinucleotide repeat containing 6B 0.145356
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.140752
LIN54 lin-54 DREAM MuvB core complex component 0.140752
UQCRB ubiquinol-cytochrome c reductase binding protein 0.136254
ANKRD50 ankyrin repeat domain 50 0.131849
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.127531
ADAT2 adenosine deaminase, tRNA-specific 2 0.127531
JAKMIP3 Janus kinase and microtubule interacting protein 3 0.127531
ISM1 isthmin 1, angiogenesis inhibitor 0.127531
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 0.123298
OSTM1 osteopetrosis associated transmembrane protein 1 0.123298
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.119151
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.115091
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.115091
CANX calnexin 0.111118
FAM216B family with sequence similarity 216, member B 0.107229
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.107229
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.103424
RASAL2 RAS protein activator like 2 0.092495
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.088999
KLHL15 kelch-like family member 15 0.085563
RCOR1 REST corepressor 1 0.082179
PRTG protogenin 0.082179
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.078844
HIPK2 homeodomain interacting protein kinase 2 0.069137
RLIM ring finger protein, LIM domain interacting 0.069137
ZNF704 zinc finger protein 704 0.065994
TLL1 tolloid-like 1 0.065994
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.065994
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.062888
JMY junction mediating and regulatory protein, p53 cofactor 0.050854
LPP LIM domain containing preferred translocation partner in lipoma 0.050854
FKBP5 FK506 binding protein 5 0.050854
ZC3H12C zinc finger CCCH-type containing 12C 0.050854
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.047969
ZBTB44 zinc finger and BTB domain containing 44 0.047969
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.045136
IGSF3 immunoglobulin superfamily, member 3 0.039622
GIGYF2 GRB10 interacting GYF protein 2 0.03694
POU2F1 POU class 2 homeobox 1 0.034317
MTF1 metal-regulatory transcription factor 1 0.029271
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.026857
DCTN5 dynactin 5 (p25) 0.026857
NKTR natural killer cell triggering receptor 0.02452
ANKRD52 ankyrin repeat domain 52 0.020071
ZNF275 zinc finger protein 275 0.017945
KIF3B kinesin family member 3B 0.011888
NAV1 neuron navigator 1 0.006367
DSC3 desmocollin 3 0.004732
ZNF618 zinc finger protein 618 0.002088