histone deacetylase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that possesses histone deacetylase activity. (Gene Ontology, GO_0000118)
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Genes

314 proteins co-occuring with the histone deacetylase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CHD4 chromodomain helicase DNA binding protein 4 2.12167
MTA1 metastasis associated 1 2.08307
HDAC9 histone deacetylase 9 2.08235
HDAC1 histone deacetylase 1 1.99405
MTA2 metastasis associated 1 family, member 2 1.96145
SIN3A SIN3 transcription regulator family member A 1.68909
HDAC2 histone deacetylase 2 1.65995
MTA3 metastasis associated 1 family, member 3 1.60943
RBBP4 retinoblastoma binding protein 4 1.55367
HDAC3 histone deacetylase 3 1.48192
SETD2 SET domain containing 2 1.38183
SAP30 Sin3A-associated protein, 30kDa 1.36197
ZFPM1 zinc finger protein, FOG family member 1 1.34065
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 1.33467
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 1.26815
NCOR1 nuclear receptor corepressor 1 1.26498
H3F3B H3 histone, family 3B (H3.3B) 1.26339
H3F3A H3 histone, family 3A 1.26339
SAP18 Sin3A-associated protein, 18kDa 1.26286
RCOR1 REST corepressor 1 1.25495
CHD3 chromodomain helicase DNA binding protein 3 1.2497
PHF21A PHD finger protein 21A 1.24131
GATAD2B GATA zinc finger domain containing 2B 1.1644
KDM1A lysine (K)-specific demethylase 1A 1.1296
MBD3 methyl-CpG binding domain protein 3 1.11429
GATAD2A GATA zinc finger domain containing 2A 1.04532
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.0258
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.994652
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.979044
MBD3L1 methyl-CpG binding domain protein 3-like 1 0.977589
HIC1 hypermethylated in cancer 1 0.964069
ARID4A AT rich interactive domain 4A (RBP1-like) 0.952573
SALL1 spalt-like transcription factor 1 0.935016
FAM60A family with sequence similarity 60, member A 0.917177
BRMS1 breast cancer metastasis suppressor 1 0.909716
BRMS1L breast cancer metastasis-suppressor 1-like 0.905996
SETD1A SET domain containing 1A 0.89672
MECP2 methyl CpG binding protein 2 0.873647
ING3 inhibitor of growth family, member 3 0.862149
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.850665
SIN3B SIN3 transcription regulator family member B 0.849287
MBD3L2 methyl-CpG binding domain protein 3-like 2 0.844696
REST RE1-silencing transcription factor 0.835974
SETDB1 SET domain, bifurcated 1 0.830466
PCCA propionyl CoA carboxylase, alpha polypeptide 0.821746
ING2 inhibitor of growth family, member 2 0.8089
EBF1 early B-cell factor 1 0.750452
ZBTB16 zinc finger and BTB domain containing 16 0.749546
HIST2H4B histone cluster 2, H4b 0.728836
HIST1H4B histone cluster 1, H4b 0.728836
HIST1H4C histone cluster 1, H4c 0.728836
HIST1H4H histone cluster 1, H4h 0.728836
HIST2H4A histone cluster 2, H4a 0.728836
HIST1H4A histone cluster 1, H4a 0.728836
HIST1H4F histone cluster 1, H4f 0.728836
HIST1H4D histone cluster 1, H4d 0.728836
HIST1H4E histone cluster 1, H4e 0.728836
HIST1H4K histone cluster 1, H4k 0.728836
HIST1H4J histone cluster 1, H4j 0.728836
HIST1H4I histone cluster 1, H4i 0.728836
HIST4H4 histone cluster 4, H4 0.728389
HIST1H4L histone cluster 1, H4l 0.728389
EGLN2 egl-9 family hypoxia-inducible factor 2 0.716346
ZNF157 zinc finger protein 157 0.711465
RNF220 ring finger protein 220 0.711465
ZFHX4 zinc finger homeobox 4 0.696465
MBD2 methyl-CpG binding domain protein 2 0.696465
ZNF521 zinc finger protein 521 0.696026
HDAC4 histone deacetylase 4 0.695148
TMEM71 transmembrane protein 71 0.660776
JDP2 Jun dimerization protein 2 0.654741
ARID4B AT rich interactive domain 4B (RBP1-like) 0.634159
ZNF22 zinc finger protein 22 0.626483
NCOR2 nuclear receptor corepressor 2 0.626057
ZNF423 zinc finger protein 423 0.622229
SAP25 Sin3A-associated protein, 25kDa 0.622229
SKI SKI proto-oncogene 0.612471
RBBP7 retinoblastoma binding protein 7 0.609932
ZGPAT zinc finger, CCCH-type with G patch domain 0.602752
HDAC5 histone deacetylase 5 0.594753
ZNF827 zinc finger protein 827 0.594332
PIAS2 protein inhibitor of activated STAT, 2 0.589714
RNF144A ring finger protein 144A 0.587199
CARM1 coactivator-associated arginine methyltransferase 1 0.580504
KAT7 K(lysine) acetyltransferase 7 0.572578
HESX1 HESX homeobox 1 0.560528
KLF10 Kruppel-like factor 10 0.554732
ZNF467 zinc finger protein 467 0.553905
STK17A serine/threonine kinase 17a 0.551838
NANOG Nanog homeobox 0.542352
EFCAB6 EF-hand calcium binding domain 6 0.537005
SALL4 spalt-like transcription factor 4 0.535361
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.53454
MYB v-myb avian myeloblastosis viral oncogene homolog 0.530028
KMT2E lysine (K)-specific methyltransferase 2E 0.52675
PHF6 PHD finger protein 6 0.523476
ZBTB7A zinc finger and BTB domain containing 7A 0.519798
ZFPM2 zinc finger protein, FOG family member 2 0.516532
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.512862
RUNX1 runt-related transcription factor 1 0.51164
TP53 tumor protein p53 0.510826
CIR1 corepressor interacting with RBPJ, 1 0.509604
FAM64A family with sequence similarity 64, member A 0.509197
GFI1B growth factor independent 1B transcription repressor 0.508383
MBD5 methyl-CpG binding domain protein 5 0.507977
HOXD8 homeobox D8 0.49661
ESR1 estrogen receptor 1 0.493371
ING1 inhibitor of growth family, member 1 0.490539
FOXK1 forkhead box K1 0.489731
TBL1X transducin (beta)-like 1X-linked 0.487711
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.472011
BCOR BCL6 corepressor 0.470005
KLF16 Kruppel-like factor 16 0.462798
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.460401
KDM5A lysine (K)-specific demethylase 5A 0.460001
PIAS1 protein inhibitor of activated STAT, 1 0.45641
DNAH8 dynein, axonemal, heavy chain 8 0.454418
TRIM27 tripartite motif containing 27 0.453621
GIGYF2 GRB10 interacting GYF protein 2 0.452427
CCL14 chemokine (C-C motif) ligand 14 0.449245
KLF1 Kruppel-like factor 1 (erythroid) 0.448848
FOXN3 forkhead box N3 0.441312
FOXP4 forkhead box P4 0.43696
BCL6 B-cell CLL/lymphoma 6 0.436565
ISYNA1 inositol-3-phosphate synthase 1 0.433801
CFDP1 craniofacial development protein 1 0.433012
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.426711
KAT5 K(lysine) acetyltransferase 5 0.426318
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.419644
PRMT5 protein arginine methyltransferase 5 0.414946
FOXK2 forkhead box K2 0.410259
PHF12 PHD finger protein 12 0.409479
TBL1Y transducin (beta)-like 1, Y-linked 0.40675
FOXP1 forkhead box P1 0.405582
YY1 YY1 transcription factor 0.403637
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.389296
ACTL6A actin-like 6A 0.385436
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 0.382354
KAT2B K(lysine) acetyltransferase 2B 0.378507
TBX18 T-box 18 0.377738
E2F7 E2F transcription factor 7 0.377354
EOMES eomesodermin 0.373516
MECOM MDS1 and EVI1 complex locus 0.367388
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.365095
TBX20 T-box 20 0.363185
HNMT histamine N-methyltransferase 0.361277
SAP30L SAP30-like 0.355563
SMYD2 SET and MYND domain containing 2 0.352142
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.347967
NFX1 nuclear transcription factor, X-box binding 1 0.346829
ATOH1 atonal homolog 1 (Drosophila) 0.344556
L3MBTL2 l(3)mbt-like 2 (Drosophila) 0.344556
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.343421
HIPK2 homeodomain interacting protein kinase 2 0.343421
SCRG1 stimulator of chondrogenesis 1 0.341529
ISCA2 iron-sulfur cluster assembly 2 0.340017
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.338506
PIAS3 protein inhibitor of activated STAT, 3 0.335864
METTL3 methyltransferase like 3 0.332848
RLIM ring finger protein, LIM domain interacting 0.332095
BRCA1 breast cancer 1, early onset 0.329461
TRIM28 tripartite motif containing 28 0.327581
LECT2 leukocyte cell-derived chemotaxin 2 0.317456
PAX5 paired box 5 0.316708
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.313718
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.307377
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.307377
PRMT7 protein arginine methyltransferase 7 0.307004
ZNF217 zinc finger protein 217 0.302168
LMO2 LIM domain only 2 (rhombotin-like 1) 0.298084
NRIP1 nuclear receptor interacting protein 1 0.294748
TRIM24 tripartite motif containing 24 0.292897
EGR2 early growth response 2 0.287352
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.286245
SAE1 SUMO1 activating enzyme subunit 1 0.285507
ARID1A AT rich interactive domain 1A (SWI-like) 0.281453
EGR1 early growth response 1 0.278877
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.278141
LMO1 LIM domain only 1 (rhombotin 1) 0.275569
RB1 retinoblastoma 1 0.274835
PHF19 PHD finger protein 19 0.2708
RPL26L1 ribosomal protein L26-like 1 0.270434
ABRA actin binding Rho activating protein 0.270068
TBX6 T-box 6 0.266042
ELF5 E74-like factor 5 (ets domain transcription factor) 0.260566
TET1 tet methylcytosine dioxygenase 1 0.259473
KDM3A lysine (K)-specific demethylase 3A 0.258016
ING5 inhibitor of growth family, member 5 0.257289
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.253291
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.249302
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.242076
MXD1 MAX dimerization protein 1 0.240636
TAL1 T-cell acute lymphocytic leukemia 1 0.238478
FOXG1 forkhead box G1 0.237042
MYCBP MYC binding protein 0.234533
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.231315
GBX2 gastrulation brain homeobox 2 0.22385
SIRT1 sirtuin 1 0.221025
HDAC10 histone deacetylase 10 0.219617
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.219617
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.218212
CTBP1 C-terminal binding protein 1 0.21646
LDB1 LIM domain binding 1 0.215412
SETD1B SET domain containing 1B 0.21124
CDX2 caudal type homeobox 2 0.210549
DMAP1 DNA methyltransferase 1 associated protein 1 0.207794
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.206766
SLBP stem-loop binding protein 0.206766
EWSR1 EWS RNA-binding protein 1 0.205399
HDAC6 histone deacetylase 6 0.204378
WDR77 WD repeat domain 77 0.202684
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.201335
VPRBP Vpr (HIV-1) binding protein 0.198991
GRB14 growth factor receptor-bound protein 14 0.198658
KDM5B lysine (K)-specific demethylase 5B 0.195681
HIST2H2AC histone cluster 2, H2ac 0.194698
HIST2H2AA3 histone cluster 2, H2aa3 0.194371
HIST2H2AA4 histone cluster 2, H2aa4 0.194371
GPS2 G protein pathway suppressor 2 0.193719
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.19307
PROP1 PROP paired-like homeobox 1 0.188274
PAX2 paired box 2 0.188274
E2F4 E2F transcription factor 4, p107/p130-binding 0.187646
BHLHE22 basic helix-loop-helix family, member e22 0.185777
GLI1 GLI family zinc finger 1 0.184853
SETD7 SET domain containing (lysine methyltransferase) 7 0.184547
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.180634
EDN3 endothelin 3 0.179459
SATB1 SATB homeobox 1 0.175188
RUVBL1 RuvB-like AAA ATPase 1 0.175188
ZNF222 zinc finger protein 222 0.174361
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.174087
FGF8 fibroblast growth factor 8 (androgen-induced) 0.173814
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.173003
SIRT7 sirtuin 7 0.171673
RARA retinoic acid receptor, alpha 0.170114
HSF1 heat shock transcription factor 1 0.169604
SIRT4 sirtuin 4 0.169604
MCRS1 microspherule protein 1 0.167856
CIDEB cell death-inducing DFFA-like effector b 0.167125
SIRT5 sirtuin 5 0.166884
RPL26 ribosomal protein L26 0.166167
HBG2 hemoglobin, gamma G 0.165932
TRIM10 tripartite motif containing 10 0.165231
ARID1B AT rich interactive domain 1B (SWI1-like) 0.164089
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 0.163865
TRIM26 tripartite motif containing 26 0.162117
SUMO1 small ubiquitin-like modifier 1 0.160658
AKR1C4 aldo-keto reductase family 1, member C4 0.160456
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.160053
RAD50 RAD50 homolog (S. cerevisiae) 0.158692
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.157943
TRIM15 tripartite motif containing 15 0.157039
ING4 inhibitor of growth family, member 4 0.156863
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.156863
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.139734
MXI1 MAX interactor 1, dimerization protein 0.137307
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.135798
SIRT6 sirtuin 6 0.13571
CDK7 cyclin-dependent kinase 7 0.135432
SIRT2 sirtuin 2 0.133536
SIRT3 sirtuin 3 0.133279
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.132095
CHD1 chromodomain helicase DNA binding protein 1 0.129763
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.129
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 0.12411
KNG1 kininogen 1 0.12062
MCM8 minichromosome maintenance complex component 8 0.115512
ATF2 activating transcription factor 2 0.110976
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.110224
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.109425
CNOT2 CCR4-NOT transcription complex, subunit 2 0.108952
DICER1 dicer 1, ribonuclease type III 0.107983
FGF4 fibroblast growth factor 4 0.107109
SP1 Sp1 transcription factor 0.106947
CD82 CD82 molecule 0.106429
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.105507
MYO5A myosin VA (heavy chain 12, myoxin) 0.103877
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.101432
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.101303
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.101206
TTF1 transcription termination factor, RNA polymerase I 0.101077
GATA2 GATA binding protein 2 0.100491
UBA2 ubiquitin-like modifier activating enzyme 2 0.099358
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.099358
HARS histidyl-tRNA synthetase 0.099257
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.097635
FOXH1 forkhead box H1 0.097565
SIX2 SIX homeobox 2 0.097318
RAD21 RAD21 homolog (S. pombe) 0.097175
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.097068
MAT2A methionine adenosyltransferase II, alpha 0.095951
RNF2 ring finger protein 2 0.095878
TIPIN TIMELESS interacting protein 0.094282
EGLN3 egl-9 family hypoxia-inducible factor 3 0.093867
MORF4 mortality factor 4 (pseudogene) 0.093867
NPPA natriuretic peptide A 0.093791
RSPO1 R-spondin 1 0.093216
POLI polymerase (DNA directed) iota 0.092754
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.091855
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.091815
TDG thymine-DNA glycosylase 0.091458
CHD1L chromodomain helicase DNA binding protein 1-like 0.090981
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.09074
TCF12 transcription factor 12 0.090054
CCL2 chemokine (C-C motif) ligand 2 0.089852
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.089811
THBS4 thrombospondin 4 0.089729
EGR3 early growth response 3 0.089277
WIPF2 WAS/WASL interacting protein family, member 2 0.088784
PLAUR plasminogen activator, urokinase receptor 0.088617
BIRC5 baculoviral IAP repeat containing 5 0.088409
PELP1 proline, glutamate and leucine rich protein 1 0.088117
SENP1 SUMO1/sentrin specific peptidase 1 0.088117