high endothelial venule Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Specialized area of vascular endothelium found in lymphoid organs, which express a variety of cell-adhesion molecules and is involved in lymphocyte extravasation. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004528)
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Genes

133 proteins co-occuring with the tissue high endothelial venule in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
SELL selectin L 3.0892
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 2.44204
GLYCAM1 glycosylation dependent cell adhesion molecule 1 (pseudogene) 2.36821
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.3235
CCL21 chemokine (C-C motif) ligand 21 2.26472
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 2.0423
HECA headcase homolog (Drosophila) 1.99534
CXCL13 chemokine (C-X-C motif) ligand 13 1.96409
CCL19 chemokine (C-C motif) ligand 19 1.79144
CCR7 chemokine (C-C motif) receptor 7 1.73131
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 1.56038
CD44 CD44 molecule (Indian blood group) 1.54971
ICAM1 intercellular adhesion molecule 1 1.4888
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.48223
ADGRG6 adhesion G protein-coupled receptor G6 1.41906
TK1 thymidine kinase 1, soluble 1.32777
CD300LG CD300 molecule-like family member g 1.32642
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.3192
VCAM1 vascular cell adhesion molecule 1 1.28771
CD4 CD4 molecule 1.23494
SELE selectin E 1.18601
JAM2 junctional adhesion molecule 2 1.17979
SELPLG selectin P ligand 1.15362
CXCL12 chemokine (C-X-C motif) ligand 12 1.14033
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.13545
CXCR5 chemokine (C-X-C motif) receptor 5 1.13147
NAAA N-acylethanolamine acid amidase 1.1173
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 1.10491
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.09783
EMCN endomucin 1.06338
ICAM2 intercellular adhesion molecule 2 1.03478
STAB1 stabilin 1 1.02031
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.00196
OSGEP O-sialoglycoprotein endopeptidase 0.940495
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.937488
AOC3 amine oxidase, copper containing 3 0.936629
CD34 CD34 molecule 0.927192
IL33 interleukin 33 0.924194
S1PR1 sphingosine-1-phosphate receptor 1 0.899871
CD79A CD79a molecule, immunoglobulin-associated alpha 0.89095
CXCR3 chemokine (C-X-C motif) receptor 3 0.885438
SLC26A1 solute carrier family 26 (anion exchanger), member 1 0.840769
DHCR7 7-dehydrocholesterol reductase 0.836156
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.835318
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.834061
FLT4 fms-related tyrosine kinase 4 0.824431
NKX2-3 NK2 homeobox 3 0.820666
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.804378
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.782725
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.767368
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.757845
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.746689
JAM3 junctional adhesion molecule 3 0.726097
IL18R1 interleukin 18 receptor 1 0.687592
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 0.649749
HBA1 hemoglobin, alpha 1 0.644074
ESAM endothelial cell adhesion molecule 0.643263
HBA2 hemoglobin, alpha 2 0.630718
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.623043
CXCL9 chemokine (C-X-C motif) ligand 9 0.612555
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.606514
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 0.603295
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 0.571619
FN1 fibronectin 1 0.565631
PDPN podoplanin 0.56005
TNF tumor necrosis factor 0.559254
SRRM2 serine/arginine repetitive matrix 2 0.558457
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.552093
VEGFC vascular endothelial growth factor C 0.539793
SLC26A8 solute carrier family 26 (anion exchanger), member 8 0.538209
PODXL podocalyxin-like 0.529508
LTA lymphotoxin alpha 0.518859
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.507064
PTPRC protein tyrosine phosphatase, receptor type, C 0.50275
CCL13 chemokine (C-C motif) ligand 13 0.50079
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.49844
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.488667
CD58 CD58 molecule 0.476201
AQP1 aquaporin 1 (Colton blood group) 0.461465
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.456828
LTB lymphotoxin beta (TNF superfamily, member 3) 0.451042
USH1G Usher syndrome 1G (autosomal recessive) 0.43989
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 0.436055
ACKR3 atypical chemokine receptor 3 0.43146
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.423436
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.417337
CCL5 chemokine (C-C motif) ligand 5 0.413151
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 0.409351
IL3RA interleukin 3 receptor, alpha (low affinity) 0.408592
SLC26A7 solute carrier family 26 (anion exchanger), member 7 0.405935
CCL20 chemokine (C-C motif) ligand 20 0.388912
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.371994
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.367129
EXT1 exostosin glycosyltransferase 1 0.352598
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.350001
ITGB7 integrin, beta 7 0.335968
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.332661
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.331927
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.328994
BCL6 B-cell CLL/lymphoma 6 0.320591
ICOS inducible T-cell co-stimulator 0.314772
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.313683
IPP intracisternal A particle-promoted polypeptide 0.299601
CFHR1 complement factor H-related 1 0.292793
CD68 CD68 molecule 0.292079
CETN2 centrin, EF-hand protein, 2 0.291008
LRG1 leucine-rich alpha-2-glycoprotein 1 0.288514
CD164 CD164 molecule, sialomucin 0.288158
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.284962
ZSCAN1 zinc finger and SCAN domain containing 1 0.283899
SUCLG1 succinate-CoA ligase, alpha subunit 0.283545
S1PR4 sphingosine-1-phosphate receptor 4 0.267102
ENG endoglin 0.263327
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.249329
RGS1 regulator of G-protein signaling 1 0.24676
S100A9 S100 calcium binding protein A9 0.246442
PDE9A phosphodiesterase 9A 0.245807
NT5E 5'-nucleotidase, ecto (CD73) 0.245175
SIRPA signal-regulatory protein alpha 0.238406
CD83 CD83 molecule 0.237216
CLEC1B C-type lectin domain family 1, member B 0.236332
CD5 CD5 molecule 0.232039
CD22 CD22 molecule 0.229568
RBP3 retinol binding protein 3, interstitial 0.229299
MZF1 myeloid zinc finger 1 0.22246
ADGRL1 adhesion G protein-coupled receptor L1 0.220604
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 0.21883
EPHA1 EPH receptor A1 0.215534
HDAC7 histone deacetylase 7 0.215534
TJP1 tight junction protein 1 0.214202
CD40LG CD40 ligand 0.213471
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.213112
WISP2 WNT1 inducible signaling pathway protein 2 0.212586