hesperidin-2648 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the hesperidin-2648 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD17B abhydrolase domain containing 17B
ACAN aggrecan
AMPD3 adenosine monophosphate deaminase 3
ANXA11 annexin A11
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP3B2 adaptor-related protein complex 3, beta 2 subunit
ARHGAP33 Rho GTPase activating protein 33
ARID5A AT rich interactive domain 5A (MRF1-like)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP2K BMP2 inducible kinase
C10ORF95 chromosome 10 open reading frame 95
C2ORF68 chromosome 2 open reading frame 68
CA9 carbonic anhydrase IX
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC71 coiled-coil domain containing 71
CD70 CD70 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLCA1 chloride channel accessory 1
CRIP1 cysteine-rich protein 1 (intestinal)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DIEXF digestive organ expansion factor homolog (zebrafish)
DLC1 DLC1 Rho GTPase activating protein
DMC1 DNA meiotic recombinase 1
DOCK10 dedicator of cytokinesis 10
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DVL2 dishevelled segment polarity protein 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELP6 elongator acetyltransferase complex subunit 6
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM131A family with sequence similarity 131, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FLJ21369 uncharacterized protein FLJ21369
FLJ22184
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HAO2 hydroxyacid oxidase 2 (long chain)
HEG1 heart development protein with EGF-like domains 1
HR hair growth associated
HSDL2 hydroxysteroid dehydrogenase like 2
HSF2BP heat shock transcription factor 2 binding protein
IL1B interleukin 1, beta
IL2RB interleukin 2 receptor, beta
IQSEC2 IQ motif and Sec7 domain 2
ITGA10 integrin, alpha 10
IZUMO4 IZUMO family member 4
JUN jun proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM5A lysine (K)-specific demethylase 5A
KIAA1456 KIAA1456
KRT17 keratin 17, type I
KRT24 keratin 24, type I
LAMC2 laminin, gamma 2
LEPR leptin receptor
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCM3AP minichromosome maintenance complex component 3 associated protein
MPL MPL proto-oncogene, thrombopoietin receptor
MST1R macrophage stimulating 1 receptor
MYBPC3 myosin binding protein C, cardiac
NCOA2 nuclear receptor coactivator 2
NCR2 natural cytotoxicity triggering receptor 2
NOS1 nitric oxide synthase 1 (neuronal)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OSGIN1 oxidative stress induced growth inhibitor 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDH12 protocadherin 12
PCDHB8 protocadherin beta 8
PCM1 pericentriolar material 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRMT2 protein arginine methyltransferase 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRU protein tyrosine phosphatase, receptor type, U
RARA retinoic acid receptor, alpha
RGS10 regulator of G-protein signaling 10
RPL10 ribosomal protein L10
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC35F5 solute carrier family 35, member F5
SLIT1 slit homolog 1 (Drosophila)
SLIT2 slit homolog 2 (Drosophila)
SYMPK symplekin
TBC1D19 TBC1 domain family, member 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM53 transmembrane protein 53
VASH2 vasohibin 2
XYLT1 xylosyltransferase I
ZCCHC24 zinc finger, CCHC domain containing 24
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF134 zinc finger protein 134
ZNF137P zinc finger protein 137, pseudogene
ZNF500 zinc finger protein 500
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADCY6 adenylate cyclase 6
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALG12 ALG12, alpha-1,6-mannosyltransferase
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BMP4 bone morphogenetic protein 4
C19ORF73 chromosome 19 open reading frame 73
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
CCDC134 coiled-coil domain containing 134
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD1A CD1a molecule
CD34 CD34 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DAGLA diacylglycerol lipase, alpha
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FKBP10 FK506 binding protein 10, 65 kDa
FKBP5 FK506 binding protein 5
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAMT guanidinoacetate N-methyltransferase
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GEMIN8 gem (nuclear organelle) associated protein 8
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
INTS9 integrator complex subunit 9
ITPKB inositol-trisphosphate 3-kinase B
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
KRI1 KRI1 homolog (S. cerevisiae)
KRT13 keratin 13, type I
LINC00339 long intergenic non-protein coding RNA 339
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYPD1 LY6/PLAUR domain containing 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
NPM3 nucleophosmin/nucleoplasmin 3
NRSN2 neurensin 2
NT5DC3 5'-nucleotidase domain containing 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OASL 2'-5'-oligoadenylate synthetase-like
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI1 peptidyl arginine deiminase, type I
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMEL premelanosome protein
POLL polymerase (DNA directed), lambda
PRICKLE3 prickle homolog 3 (Drosophila)
RAB3D RAB3D, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RNF146 ring finger protein 146
SDC3 syndecan 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SPINK5 serine peptidase inhibitor, Kazal type 5
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TICAM1 toll-like receptor adaptor molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
USP20 ubiquitin specific peptidase 20
VEGFB vascular endothelial growth factor B
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
XAB2 XPA binding protein 2
ZBTB48 zinc finger and BTB domain containing 48
ZNF324 zinc finger protein 324
ZNF668 zinc finger protein 668
ZNF816 zinc finger protein 816