hepatocellular carcinoma Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A liver carcinoma that has_material_basis_in undifferentiated hepatocytes. (Human Disease Ontology, DOID_684)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:684
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Genes

46 genes associated with the disease hepatocellular carcinoma in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.99483
FUT2 fucosyltransferase 2 (secretor status included) 3.51446
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 3.08092
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.6882
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 2.60668
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.40544
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.2205
FAM3B family with sequence similarity 3, member B 2.07237
RASIP1 Ras interacting protein 1 1.99432
KIF1B kinesin family member 1B 1.95032
AFP alpha-fetoprotein 1.93944
C2 complement component 2 1.91536
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 1.78856
DBP D site of albumin promoter (albumin D-box) binding protein 1.76717
SEC1P secretory blood group 1, pseudogene 1.76045
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.75616
DEPDC5 DEP domain containing 5 1.73479
MICA MHC class I polypeptide-related sequence A 1.71314
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 1.69848
RPL18 ribosomal protein L18 1.65109
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.64472
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 1.58623
STAT4 signal transducer and activator of transcription 4 1.5805
GRIK1 glutamate receptor, ionotropic, kainate 1 1.53058
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.40417
MAP1A microtubule-associated protein 1A 1.35898
CA11 carbonic anhydrase XI 1.35121
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.34633
TP53BP1 tumor protein p53 binding protein 1 1.33817
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.31941
MTMR6 myotubularin related protein 6 1.28906
LRP1B low density lipoprotein receptor-related protein 1B 1.18963
EFCAB11 EF-hand calcium binding domain 11 1.07599
CHD6 chromodomain helicase DNA binding protein 6 1.06457
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.958374
CD163L1 CD163 molecule-like 1 0.933664
SYNJ2BP synaptojanin 2 binding protein 0.846107
PC pyruvate carboxylase 0.822728
THSD7A thrombospondin, type I, domain containing 7A 0.783797
PODXL podocalyxin-like 0.743993
ADCY10 adenylate cyclase 10 (soluble) 0.733819
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.731217
C6ORF7 chromosome 6 open reading frame 7 0.712762
AJAP1 adherens junctions associated protein 1 0.711001
ZHX2 zinc fingers and homeoboxes 2 0.671205
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.609075