hepatic granulomatosis Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description The presence of multiple granulomas in the liver as based on pathological examination. Granulomas are small 0.5 to 2 mm collections of modified macrophages called epithelioid cells usually surrounded by lymphocytes. (Human Phenotype Ontology, HP_0011955)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0011955
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Genes

66 genes associated with the hepatic granulomatosis phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
HLA-B major histocompatibility complex, class I, B 2.16544
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.97023
IL10 interleukin 10 1.87101
CCHCR1 coiled-coil alpha-helical rod protein 1 1.63667
MICA MHC class I polypeptide-related sequence A 1.58519
MOG myelin oligodendrocyte glycoprotein 1.47754
ERAP1 endoplasmic reticulum aminopeptidase 1 1.45654
C6ORF15 chromosome 6 open reading frame 15 1.4378
ZNRD1-AS1 ZNRD1 antisense RNA 1 1.40136
HCP5 HLA complex P5 (non-protein coding) 1.39971
KLRC4 killer cell lectin-like receptor subfamily C, member 4 1.35521
STAT4 signal transducer and activator of transcription 4 1.35521
PSORS1C2 psoriasis susceptibility 1 candidate 2 1.29852
TFCP2L1 transcription factor CP2-like 1 1.28282
HLA-F-AS1 HLA-F antisense RNA 1 1.23829
MICB MHC class I polypeptide-related sequence B 1.19327
DDR1 discoidin domain receptor tyrosine kinase 1 1.13501
DPCR1 diffuse panbronchiolitis critical region 1 1.12677
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.07502
LTA lymphotoxin alpha 1.0118
HCG18 HLA complex group 18 (non-protein coding) 1.00697
RNF175 ring finger protein 175 0.986868
TRIM26 tripartite motif containing 26 0.981095
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.979804
FOXP1 forkhead box P1 0.929444
CLASP2 cytoplasmic linker associated protein 2 0.926966
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 0.907652
VARS2 valyl-tRNA synthetase 2, mitochondrial 0.905315
ATP6V1G2-DDX39B ATP6V1G2-DDX39B readthrough (NMD candidate) 0.900455
CCDC180 coiled-coil domain containing 180 0.896026
ASTN2 astrotactin 2 0.88947
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.877388
HLA-F major histocompatibility complex, class I, F 0.874717
SFTA2 surfactant associated 2 0.873556
GPM6A glycoprotein M6A 0.834343
POU5F1 POU class 5 homeobox 1 0.83069
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.825497
CSMD1 CUB and Sushi multiple domains 1 0.819829
HCG27 HLA complex group 27 (non-protein coding) 0.811465
FBXL2 F-box and leucine-rich repeat protein 2 0.80501
MUC22 mucin 22 0.799669
DOCK4 dedicator of cytokinesis 4 0.787244
UBP1 upstream binding protein 1 (LBP-1a) 0.766212
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.765722
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.759303
DCC DCC netrin 1 receptor 0.752816
ZC3H13 zinc finger CCCH-type containing 13 0.745419
WDFY4 WDFY family member 4 0.737679
EFCAB11 EF-hand calcium binding domain 11 0.70642
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.703538
MDC1 mediator of DNA-damage checkpoint 1 0.703184
JARID2 jumonji, AT rich interactive domain 2 0.692469
IL1R2 interleukin 1 receptor, type II 0.679051
WWTR1 WW domain containing transcription regulator 1 0.671056
CCDC42 coiled-coil domain containing 42 0.65006
LOC100287329 uncharacterized LOC100287329 0.623859
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.605515
FXYD5 FXYD domain containing ion transport regulator 5 0.604822
FYCO1 FYVE and coiled-coil domain containing 1 0.598797
ILDR1 immunoglobulin-like domain containing receptor 1 0.595442
CDHR3 cadherin-related family member 3 0.592349
CDSN corneodesmosin 0.584397
TCF19 transcription factor 19 0.574666
CPVL carboxypeptidase, vitellogenic-like 0.572823
UBAC2 UBA domain containing 2 0.466578
UBASH3B ubiquitin associated and SH3 domain containing B 0.438588