heart valve Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A structure especially in a vein or lymphatic that closes temporarily a passage or orifice or permits movement of fluid in one direction only. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000564)
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Genes

191 proteins co-occuring with the tissue heart valve in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
VKORC1 vitamin K epoxide reductase complex, subunit 1 2.26526
F2 coagulation factor II (thrombin) 1.8087
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.62207
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 1.54488
GGCX gamma-glutamyl carboxylase 1.38367
GALNS galactosamine (N-acetyl)-6-sulfatase 1.29265
VWF von Willebrand factor 1.23762
F3 coagulation factor III (thromboplastin, tissue factor) 1.20467
FN1 fibronectin 1 1.18512
PLAT plasminogen activator, tissue 1.16826
ARSB arylsulfatase B 1.15008
IDUA iduronidase, alpha-L- 1.08148
P4HB prolyl 4-hydroxylase, beta polypeptide 1.0806
HBA1 hemoglobin, alpha 1 1.06956
HBA2 hemoglobin, alpha 2 1.05501
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.03609
SUMF1 sulfatase modifying factor 1 1.01375
RAB39B RAB39B, member RAS oncogene family 0.939206
TWIST1 twist family bHLH transcription factor 1 0.928478
TBX20 T-box 20 0.924623
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.916923
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.916069
TIFA TRAF-interacting protein with forkhead-associated domain 0.914788
TNNI3 troponin I type 3 (cardiac) 0.907109
VCAN versican 0.905404
HPR haptoglobin-related protein 0.89647
SCAI suppressor of cancer cell invasion 0.883744
MGP matrix Gla protein 0.874862
SOX9 SRY (sex determining region Y)-box 9 0.866842
TNC tenascin C 0.863048
HP haptoglobin 0.859258
SPP1 secreted phosphoprotein 1 0.836995
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 0.799791
PF4 platelet factor 4 0.78231
ASB14 ankyrin repeat and SOCS box containing 14 0.781063
CRP C-reactive protein, pentraxin-related 0.760742
BGN biglycan 0.747102
ALB albumin 0.746277
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.741327
RHPN2 rhophilin, Rho GTPase binding protein 2 0.740503
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.733912
NOS3 nitric oxide synthase 3 (endothelial cell) 0.731854
TGFB3 transforming growth factor, beta 3 0.731442
TGFB1 transforming growth factor, beta 1 0.713779
F8 coagulation factor VIII, procoagulant component 0.689634
MMP2 matrix metallopeptidase 2 0.688
ACE angiotensin I converting enzyme 0.674543
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.667622
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.662336
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.661116
PKP2 plakophilin 2 0.640023
CD68 CD68 molecule 0.633549
FICD FIC domain containing 0.626273
ACOT13 acyl-CoA thioesterase 13 0.624254
C1ORF167 chromosome 1 open reading frame 167 0.623446
COL3A1 collagen, type III, alpha 1 0.60893
FZD2 frizzled class receptor 2 0.58242
LECT1 leukocyte cell derived chemotaxin 1 0.58242
ADGRL2 adhesion G protein-coupled receptor L2 0.579617
MEGF6 multiple EGF-like-domains 6 0.576816
BMP2 bone morphogenetic protein 2 0.576415
COL2A1 collagen, type II, alpha 1 0.573217
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.573217
ZFPM2 zinc finger protein, FOG family member 2 0.56284
PTH1R parathyroid hormone 1 receptor 0.551298
ALPL alkaline phosphatase, liver/bone/kidney 0.546929
MATK megakaryocyte-associated tyrosine kinase 0.544946
APC2 adenomatosis polyposis coli 2 0.542566
ARSH arylsulfatase family, member H 0.539396
DCN decorin 0.536625
COL12A1 collagen, type XII, alpha 1 0.535042
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.531484
FBLN1 fibulin 1 0.525166
TGFB2 transforming growth factor, beta 2 0.522011
ALPPL2 alkaline phosphatase, placental-like 2 0.516104
ALPP alkaline phosphatase, placental 0.51453
FGF2 fibroblast growth factor 2 (basic) 0.511778
INA internexin neuronal intermediate filament protein, alpha 0.507849
DEFB105B defensin, beta 105B 0.507064
NOTCH1 notch 1 0.491009
F5 coagulation factor V (proaccelerin, labile factor) 0.481648
MMP9 matrix metallopeptidase 9 0.476979
MMP13 matrix metallopeptidase 13 0.465723
PROS1 protein S (alpha) 0.459532
PROM1 prominin 1 0.457214
SPATA5 spermatogenesis associated 5 0.45567
BMP4 bone morphogenetic protein 4 0.450657
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.443347
MSX1 msh homeobox 1 0.442578
TTR transthyretin 0.44181
CEP104 centrosomal protein 104kDa 0.441042
ACKR3 atypical chemokine receptor 3 0.434906
CDH5 cadherin 5, type 2 (vascular endothelium) 0.432991
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.432225
PRELP proline/arginine-rich end leucine-rich repeat protein 0.429165
PRKD2 protein kinase D2 0.428783
ARSD arylsulfatase D 0.413151
TIMP4 TIMP metallopeptidase inhibitor 4 0.410111
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.40328
RAD23B RAD23 homolog B (S. cerevisiae) 0.399492
SUMF2 sulfatase modifying factor 2 0.399492
COL5A2 collagen, type V, alpha 2 0.399492
TAGLN transgelin 0.391931
CCDC88A coiled-coil domain containing 88A 0.38326
ARSE arylsulfatase E (chondrodysplasia punctata 1) 0.382131
BGLAP bone gamma-carboxyglutamate (gla) protein 0.381379
PHB prohibitin 0.380627
ICAM1 intercellular adhesion molecule 1 0.376119
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.361155
THY1 Thy-1 cell surface antigen 0.359664
IGLV3-10 immunoglobulin lambda variable 3-10 0.358546
WDFY2 WD repeat and FYVE domain containing 2 0.355198
GPR182 G protein-coupled receptor 182 0.350743
TSPO translocator protein (18kDa) 0.346668
CLCN6 chloride channel, voltage-sensitive 6 0.346668
TMEM51 transmembrane protein 51 0.342971
RUNX2 runt-related transcription factor 2 0.341126
MIR15B microRNA 15b 0.337072
MYH9 myosin, heavy chain 9, non-muscle 0.336336
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.334865
CALU calumenin 0.333028
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.328628
ADAM19 ADAM metallopeptidase domain 19 0.327164
CUTA cutA divalent cation tolerance homolog (E. coli) 0.318042
IBSP integrin-binding sialoprotein 0.316951
VEGFA vascular endothelial growth factor A 0.316224
PDZD4 PDZ domain containing 4 0.315861
HEBP1 heme binding protein 1 0.315498
SSB Sjogren syndrome antigen B (autoantigen La) 0.311507
PTH parathyroid hormone 0.311145
EMILIN1 elastin microfibril interfacer 1 0.309335
MIR93 microRNA 93 0.306805
COL1A2 collagen, type I, alpha 2 0.305001
ORM1 orosomucoid 1 0.301758
CD34 CD34 molecule 0.301398
HEYL hes-related family bHLH transcription factor with YRPW motif-like 0.298165
GJA8 gap junction protein, alpha 8, 50kDa 0.29673
GFER growth factor, augmenter of liver regeneration 0.296013
SEPT2 septin 2 0.294939
VCAM1 vascular cell adhesion molecule 1 0.294939
CWC15 CWC15 spliceosome-associated protein 0.294581
HAS2 hyaluronan synthase 2 0.292079
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.292079
LTBP2 latent transforming growth factor beta binding protein 2 0.290652
INS insulin 0.286026
FBN1 fibrillin 1 0.282837
MIR100 microRNA 100 0.280717
HGD homogentisate 1,2-dioxygenase 0.280717
PERP PERP, TP53 apoptosis effector 0.279659
EFNA3 ephrin-A3 0.279307
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.2779
HAPLN1 hyaluronan and proteoglycan link protein 1 0.275794
SOX8 SRY (sex determining region Y)-box 8 0.274394
COL11A1 collagen, type XI, alpha 1 0.273346
F9 coagulation factor IX 0.271604
HBEGF heparin-binding EGF-like growth factor 0.270214
KNG1 kininogen 1 0.269867
AHSG alpha-2-HS-glycoprotein 0.269174
GUSB glucuronidase, beta 0.269174
AMPD3 adenosine monophosphate deaminase 3 0.267446
ACTA1 actin, alpha 1, skeletal muscle 0.266757
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.265381
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.261624
FAM83H family with sequence similarity 83, member H 0.259591
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.25858
STAB1 stabilin 1 0.258243
PTPRB protein tyrosine phosphatase, receptor type, B 0.257572
PPCS phosphopantothenoylcysteine synthetase 0.24804
ENO1 enolase 1, (alpha) 0.24486
RNF112 ring finger protein 112 0.243605
KIF21A kinesin family member 21A 0.243605
GATA4 GATA binding protein 4 0.24052
OVGP1 oviductal glycoprotein 1, 120kDa 0.238108
TIMP1 TIMP metallopeptidase inhibitor 1 0.237513
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.237513
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.234302
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 0.234016
FBLN2 fibulin 2 0.230656
PTOV1 prostate tumor overexpressed 1 0.23011
ELN elastin 0.229839
RNASEH2A ribonuclease H2, subunit A 0.227186
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.225144
F10 coagulation factor X 0.22415
SHB Src homology 2 domain containing adaptor protein B 0.22246
AMPD2 adenosine monophosphate deaminase 2 0.221521
APOA1 apolipoprotein A-I 0.219264
LDHA lactate dehydrogenase A 0.218186
CA2 carbonic anhydrase II 0.218186
TIMP3 TIMP metallopeptidase inhibitor 3 0.217346
MMP1 matrix metallopeptidase 1 0.215928
CD44 CD44 molecule (Indian blood group) 0.215147