hantavirus pulmonary syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in infection located_in lung, has_material_basis_in Sin Nombre virus, transmitted_by deer mouse (Myodes glareolus), has_material_basis_in Black Creek Canal virus, transmitted_by cotton rat (Sigmodon hispidus), has_material_basis_in Bayou virus, transmitted_by marsh rice rat (Oryzomys palustris), has_material_basis_in Laguna Negra virus, transmitted_by small vesper mouse (Calomys laucha), or has_material_basis_in Andes virus, transmitted_by rice rat (Oligoryzomys longicaudatus). The infection has_symptom fever, has_symptom muscle pain, has_symptom headache, has_symptom cough, has_symptom vomiting, has_symptom chills which rapidly progress to bilateral interstitial pulmonary infiltrates occurrence, pulmonary edema and hypoxia often resulting in death from shock or cardiac complications. (Human Disease Ontology, DOID_14472)
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Genes

48 genes co-occuring with the disease hantavirus pulmonary syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.23777
IRF3 interferon regulatory factor 3 1.1507
FETUB fetuin B 1.10258
ANGPT4 angiopoietin 4 1.04672
RND1 Rho family GTPase 1 1.00161
BHLHE22 basic helix-loop-helix family, member e22 0.922149
SEBOX SEBOX homeobox 0.911022
CDH5 cadherin 5, type 2 (vascular endothelium) 0.909787
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 0.890898
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.845031
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.820847
FAM20C family with sequence similarity 20, member C 0.790492
RAET1E retinoic acid early transcript 1E 0.785984
SPRED1 sprouty-related, EVH1 domain containing 1 0.767985
MAVS mitochondrial antiviral signaling protein 0.641433
EGLN3 egl-9 family hypoxia-inducible factor 3 0.636708
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.635135
HLA-DOB major histocompatibility complex, class II, DO beta 0.629242
HOXA1 homeobox A1 0.615529
SYK spleen tyrosine kinase 0.579661
DAXX death-domain associated protein 0.577716
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.524588
TRAF3 TNF receptor-associated factor 3 0.503441
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.475255
FBN2 fibrillin 2 0.454093
RICTOR RPTOR independent companion of MTOR, complex 2 0.452962
SLPI secretory leukocyte peptidase inhibitor 0.444676
CFD complement factor D (adipsin) 0.428516
TNF tumor necrosis factor 0.42589
LIG3 ligase III, DNA, ATP-dependent 0.358551
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.350084
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.3292
F3 coagulation factor III (thromboplastin, tissue factor) 0.325916
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.321909
FYN FYN proto-oncogene, Src family tyrosine kinase 0.300894
LYN LYN proto-oncogene, Src family tyrosine kinase 0.288668
VEGFA vascular endothelial growth factor A 0.280796
MX1 MX dynamin-like GTPase 1 0.260891
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.258064
ANGPT1 angiopoietin 1 0.251366
KRT18 keratin 18, type I 0.251366
F12 coagulation factor XII (Hageman factor) 0.239101
CD83 CD83 molecule 0.231102
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.225229
LTA lymphotoxin alpha 0.215314
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.199681
CD59 CD59 molecule, complement regulatory protein 0.197742
VEGFC vascular endothelial growth factor C 0.164359