haloperidol-5200 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the haloperidol-5200 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADARB1 adenosine deaminase, RNA-specific, B1
AGFG2 ArfGAP with FG repeats 2
ALOXE3 arachidonate lipoxygenase 3
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APOM apolipoprotein M
ARMC4 armadillo repeat containing 4
ASPH aspartate beta-hydroxylase
CALD1 caldesmon 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC28B coiled-coil domain containing 28B
CD248 CD248 molecule, endosialin
CD6 CD6 molecule
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CNR2 cannabinoid receptor 2 (macrophage)
COL6A1 collagen, type VI, alpha 1
COMT catechol-O-methyltransferase
CRY2 cryptochrome circadian clock 2
DDN dendrin
DRD2 dopamine receptor D2
EDA ectodysplasin A
EFR3B EFR3 homolog B (S. cerevisiae)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FBXO2 F-box protein 2
FGF16 fibroblast growth factor 16
FGFBP1 fibroblast growth factor binding protein 1
FLJ21369 uncharacterized protein FLJ21369
GFI1 growth factor independent 1 transcription repressor
GJA8 gap junction protein, alpha 8, 50kDa
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR157 G protein-coupled receptor 157
GSK3A glycogen synthase kinase 3 alpha
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUK1 guanylate kinase 1
HAND1 heart and neural crest derivatives expressed 1
HCRP1 hepatocellular carcinoma-related HCRP1
HFE hemochromatosis
HHAT hedgehog acyltransferase
HHLA1 HERV-H LTR-associating 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
ITGA8 integrin, alpha 8
ITPK1 inositol-tetrakisphosphate 1-kinase
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLHL25 kelch-like family member 25
LAMP1 lysosomal-associated membrane protein 1
MATN1 matrilin 1, cartilage matrix protein
MEG3 maternally expressed 3 (non-protein coding)
MIER2 mesoderm induction early response 1, family member 2
MOCS1 molybdenum cofactor synthesis 1
MSMB microseminoprotein, beta-
MST1L macrophage stimulating 1-like
MTCP1 mature T-cell proliferation 1
MUC4 mucin 4, cell surface associated
NCR2 natural cytotoxicity triggering receptor 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLRX1 NLR family member X1
NMT1 N-myristoyltransferase 1
NNMT nicotinamide N-methyltransferase
NOX1 NADPH oxidase 1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OXCT2 3-oxoacid CoA transferase 2
PARVA parvin, alpha
PAX8 paired box 8
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP prolactin-induced protein
PLA2G3 phospholipase A2, group III
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLQ polymerase (DNA directed), theta
POU3F4 POU class 3 homeobox 4
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PROL1 proline rich, lacrimal 1
PRY PTPN13-like, Y-linked
PSEN2 presenilin 2
RALGDS ral guanine nucleotide dissociation stimulator
RETN resistin
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A13 S100 calcium binding protein A13
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC2 syndecan 2
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC43A3 solute carrier family 43, member 3
SPTBN5 spectrin, beta, non-erythrocytic 5
SSPN sarcospan
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TUBA3C tubulin, alpha 3c
UBXN1 UBX domain protein 1
WIPF1 WAS/WASL interacting protein family, member 1
XAF1 XIAP associated factor 1
XDH xanthine dehydrogenase
ZNF10 zinc finger protein 10
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
AKAP12 A kinase (PRKA) anchor protein 12
AKIP1 A kinase (PRKA) interacting protein 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
ANO10 anoctamin 10
ARMC6 armadillo repeat containing 6
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARPIN actin-related protein 2/3 complex inhibitor
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP2 activating transcription factor 7 interacting protein 2
BATF basic leucine zipper transcription factor, ATF-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CGA glycoprotein hormones, alpha polypeptide
CHD8 chromodomain helicase DNA binding protein 8
CIC capicua transcriptional repressor
CLDN15 claudin 15
CUEDC1 CUE domain containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DUSP2 dual specificity phosphatase 2
DVL1 dishevelled segment polarity protein 1
EFNA3 ephrin-A3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EXO5 exonuclease 5
FAAH fatty acid amide hydrolase
FAM155B family with sequence similarity 155, member B
FANCC Fanconi anemia, complementation group C
FKBP14 FK506 binding protein 14, 22 kDa
GALK1 galactokinase 1
GBP2 guanylate binding protein 2, interferon-inducible
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPATCH3 G patch domain containing 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AM histone cluster 1, H2am
HIST1H3B histone cluster 1, H3b
HOOK1 hook microtubule-tethering protein 1
HSPA1L heat shock 70kDa protein 1-like
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAT2A K(lysine) acetyltransferase 2A
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRP3 low density lipoprotein receptor-related protein 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MANBA mannosidase, beta A, lysosomal
MITF microphthalmia-associated transcription factor
MXD3 MAX dimerization protein 3
N4BP3 NEDD4 binding protein 3
NABP2 nucleic acid binding protein 2
NDRG4 NDRG family member 4
NRGN neurogranin (protein kinase C substrate, RC3)
NRSN2 neurensin 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PHACTR4 phosphatase and actin regulator 4
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPT2 palmitoyl-protein thioesterase 2
PRR14L proline rich 14-like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFTN1 raftlin, lipid raft linker 1
RNF19B ring finger protein 19B
RPGR retinitis pigmentosa GTPase regulator
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC16A6 solute carrier family 16, member 6
SLC46A3 solute carrier family 46, member 3
SRD5A3 steroid 5 alpha-reductase 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYTL2 synaptotagmin-like 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX19 T-box 19
TCTN2 tectonic family member 2
TEP1 telomerase-associated protein 1
TFIP11 tuftelin interacting protein 11
TMEM159 transmembrane protein 159
TRIM45 tripartite motif containing 45
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668